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Demographic characteristics of 3,659 Japanese patients with obstructive sleep apnea–hypopnea syndrome diagnosed by full polysomnography: associations with apnea–hypopnea index

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Abstract

Information on obstructive sleep apnea–hypopnea syndrome (OSAHS) in Japan has been limited. The purposes of this clinical study were to evaluate the demographic characteristics of Japanese OSAHS patients and to assess how demographic factors are associated with OSAHS severity. We analyzed 3,659 OSAHS patients who underwent polysomnographic evaluation between January 2000 and December 2004 at 11 hospitals in Niigata Prefecture, Japan. Data consisted of apnea–hypopnea index (AHI) and demographic characteristics, including sex, age, and body-mass index, for statistical analysis. Levels of obesity were classified according to the WHO criteria. The male-to-female patient ratio for OSAHS was 4.6, and male patients presented more severe OSAHS than female patients. High AHI and a high proportion of moderate to serious OSAHS (AHI ≥ 15) were found among the patients in their 30s, as well as female patients in their 70s and male patients in their 80s. The AHI and the proportion of moderate-to-serious OSAHS (AHI ≥ 15) were greater in patients classified as underweight than in normal weight patients. In conclusion, there is a higher male predominance in the prevalence of OSAHS, and in both sexes, the results suggest different pathophysiological mechanisms of deteriorating OSAHS between adults under age 55 and adults 55 years or over. In addition, underweight patients exhibit more severe OSAHS than normal weight patients.

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Acknowledgement

The authors wish to acknowledge the valuable support of Drs Hideo Sato (Nagaoka Chuou General Hospital), Jouji Toyama, Haruhiko Nakajima, Shin-ichi Kinebuchi (Joetsu General Hospital), and Kunihiko Sakai (Division of Respiratory Medicine, Nishi-Niigata Chuo National Hospital) in data collection for this study.

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Authors and Affiliations

  1. Department of Community Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata, 951-8510, Japan

    Fumi Ohdaira, Kazutoshi Nakamura & Masaharu Yamamoto

  2. Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata, 951-8510, Japan

    Hideaki Nakayama & Fumitake Gejyo

  3. Department of Sleep Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan

    Makoto Satoh

  4. Division of Medicine, Joetsu General Hospital, Niigata, Japan

    Makoto Satoh

  5. Division of Respiratory Medicine, Nishi-Niigata Chuo National Hospital, Niigata, Japan

    Tetsuro Ohdaira

  6. Division of Respiratory Medicine, Niigata Rinko Hospital, Niigata, Japan

    Masami Nakamata

  7. Nippon Dental University Niigata Hospital, Niigata, Japan

    Masaki Kohno

  8. Division of Respiratory Medicine, Center of Respiratory Disease, Nagaoka Chuou General Hospital, Niigata, Japan

    Akira Iwashima

  9. Department of Psychiatry, Koseiren-Kariwagun General Hospital, Niigata, Japan

    Akira Onda

  10. Sado General Hospital, Niigata, Japan

    Yoshiaki Kobayashi

  11. Department of Internal Medicine, Niigata Prefectural Kamo Hospital, Niigata, Japan

    Katsuya Fujimori

  12. Tachikawa General Hospital, Niigata, Japan

    Toshio Kiguchi

  13. Department of Otolaryngology, Kido Hospital, Niigata, Japan

    Shuji Izumi

  14. Division of Reconstructive Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata, 951-8510, Japan

    Tadaharu Kobayashi

  15. Department of Otolaryngology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata, 951-8510, Japan

    Hideo Shinoda & Sugata Takahashi

Authors
  1. Fumi Ohdaira
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  2. Kazutoshi Nakamura
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  3. Hideaki Nakayama
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  4. Makoto Satoh
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  5. Tetsuro Ohdaira
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  6. Masami Nakamata
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  7. Masaki Kohno
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  8. Akira Iwashima
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  9. Akira Onda
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  10. Yoshiaki Kobayashi
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  11. Katsuya Fujimori
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  12. Toshio Kiguchi
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  13. Shuji Izumi
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  14. Tadaharu Kobayashi
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  15. Hideo Shinoda
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  16. Sugata Takahashi
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  17. Fumitake Gejyo
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  18. Masaharu Yamamoto
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Corresponding author

Correspondence to Kazutoshi Nakamura.

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Ohdaira, F., Nakamura, K., Nakayama, H. et al. Demographic characteristics of 3,659 Japanese patients with obstructive sleep apnea–hypopnea syndrome diagnosed by full polysomnography: associations with apnea–hypopnea index. Sleep Breath 11, 93–101 (2007). https://doi.org/10.1007/s11325-006-0087-5

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  • DOI: https://doi.org/10.1007/s11325-006-0087-5

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