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10.01.2018 | Sleep Breathing Physiology and Disorders • Original Article

Comorbid insomnia and sleep apnea in Veterans with post-traumatic stress disorder

verfasst von: Ali A. El-Solh, David Adamo, Thomas Kufel

Erschienen in: Sleep and Breathing | Ausgabe 1/2018

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Abstract

Purpose

The purpose of this study was to determine the impact of insomnia in Veterans with post-traumatic stress disorder (PTSD) and obstructive sleep apnea (OSA) on health-related outcomes before and after 12 weeks of continuous positive airway pressure (CPAP) treatment.

Methods

We conducted a prospective cohort study of Veterans with PTSD and documented apnea hypopnea index (AHI) ≥ 5 with and without clinically significant insomnia as determined by the Insomnia Severity Index (ISI). Health-related outcomes including PTSD checklist (PCL-M), SF-36, and Pittsburgh Sleep Quality Index (PSQI) were assessed at baseline and 12 weeks after initiation of OSA treatment. CPAP adherence was retrieved at each visit.

Results

Seventy-two Veterans including 36 with comorbid insomnia and OSA (COMISA) and 36 OSA-only were enrolled. Veterans with COMISA were younger (p = 0.03), had lower BMI (p < 0.001), and were more likely to report depression than those with OSA-only (p = 0.004). Although AHI was higher in the COMISA (p = 0.01), both groups expressed comparable daytime sleepiness (p = 0.16). The COMISA group had no significant change in SF-36 and PSQI after 12 weeks of treatment and used CPAP much less frequently than OSA-only group (p = 0.001).

Conclusions

COMISA in Veterans with PTSD is associated with worse quality of life than those with OSA-only. Insomnia should be assessed in Veterans with PTSD who are not adherent to CPAP treatment.

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Titel: Comorbid insomnia and sleep apnea in Veterans with post-traumatic stress disorder
verfasst von: Ali A. El-Solh
David Adamo
Thomas Kufel
Publikationsdatum: 10.01.2018
Verlag: Springer International Publishing
Erschienen in: Sleep and Breathing / Ausgabe 1/2018
Print ISSN: 1520-9512
Elektronische ISSN: 1522-1709
DOI: https://doi.org/10.1007/s11325-017-1618-y

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Comorbid insomnia and sleep apnea in Veterans with post-traumatic stress disorder

Abstract

Purpose

Methods

Results

Conclusions

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