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Comparison of 3D ultrasound and magnetic resonance imaging for microwave ablation in the canine splenomegaly model

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International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Purpose

Microwave ablation is used for the treatment of hypersplenism. Image guidance and ablation volume assessment is important to ensure that the ablation is successful. The accuracy of 3D ultrasound (US) and magnetic resonance imaging (MRI) in determining the parameters for microwave ablation were compared in a canine splenomegaly model.

Methods

Microwave ablation of the spleen was performed on 13 dogs with congestive splenomegaly. Several combinations of power output and ablation time were used: 60 W for 300 s, 50 W for 360 s and 40 W for 450 s. The ablation zone volume was measured by 3D US and 3D MRI immediately after microwave ablation, and at 1, 2 and 8 weeks thereafter.

Results

Compared with 3D MRI, the ablation zone reconstruction rate was lower with 3D US (92 vs. 100 %). However, there was no significant difference was found in the ablation volume calculated soon after the treatment and 1 week and 2 months later.

Conclusion

3D US may be useful for quantifying the volume of microwave ablation zones in the spleens of experimental animals and appears promising as an alterative modality to MRI for clinical examinations.

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Conflict of interest

None to declare.

Author information

Authors and Affiliations

  1. Department of Interventional Ultrasound, Yuquan Hosiptal, Tsinghua University, No. 5 of Shijingshan Road, Shijingshan District, Beijing, 100049, China

    Lin Sheng

  2. Fuda Cancer Hospital, Jinan University School of Medicine, No. 2 Tangdexi Road, Tianhe District, Guangzhou, 510665, China

    Jialiang Li & Jibing Chen

  3. Department of Interventional Ultrasound, Chinese PLA General Hospital, Beijing, 100853, China

    Ping Liang & Baowei Dong

Authors
  1. Lin Sheng
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  2. Jialiang Li
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  3. Jibing Chen
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  4. Ping Liang
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  5. Baowei Dong
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Corresponding author

Correspondence to Ping Liang.

Additional information

This study was supported by the National Natural Science Foundation of People’s Republic of China (No. 30371367), and the Ministry of Science and Technology of People’s Republic of China (No. 2004BA714B10).

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Sheng, L., Li, J., Chen, J. et al. Comparison of 3D ultrasound and magnetic resonance imaging for microwave ablation in the canine splenomegaly model. Int J CARS 10, 459–464 (2015). https://doi.org/10.1007/s11548-014-1095-8

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  • DOI: https://doi.org/10.1007/s11548-014-1095-8

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