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International Journal of Computer Assisted Radiology and Surgery

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07.11.2020 | Original Article

Development and evaluation of a prototype detector for an intraoperative laparoscopic coincidence imaging system with PET tracers

verfasst von: Madhushanka R. Liyanaarachchi, Kenji Shimazoe, Hiroyuki Takahashi, Keiichi Nakagawa, Etsuko Kobayashi, Ichiro Sakuma

Erschienen in: International Journal of Computer Assisted Radiology and Surgery | Ausgabe 1/2021

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Abstract

Purpose

Conventional positron emission tomography can be used only preoperatively to identify lymph node metastases, and hence, these growths are difficult to locate intraoperatively. Previously, an intraoperative laparoscopic coincidence imaging system, with an external fixed detector array and a detector probe that can be moved and inserted into the stomach, was proposed to identify lymph node metastases during stomach cancer surgery. This paper proposes a prototype detector for this system.

Methods

GAGG:Ce (Gd₃Al₂Ga₃O₁₂:Ce) scintillator crystals, one to one coupled with silicon photomultipliers (SiPMs), were used to identify 511 keV photons. An optical tracking system followed the position and orientation of the movable detector. SiPM outputs were read out by time-over-threshold (TOT)-based application-specific integrated circuits, which converted the electrical charges into digital pulses. To identify the arrival time, channel number, and pulse width, which indicate the energy information of each TOT output, a data acquisition system was developed based on a field-programmable gate array.

Results

The spatial resolution of the reconstructed images in lateral direction was better than 7 mm, but that of depth direction was limited, owing to inadequate projections. The prototype successfully reconstructed 44 kBq ¹⁸F-fluorodeoxyglucose sources during a 2-min scan.

Conclusion

We developed a prototype detector for an intraoperative laparoscopic coincidence imaging system. The prototype detector was evaluated successfully, and the produced images were similar to those obtained in the simulation results, thereby suggesting that this method offers a new possibility of imaging lymph node metastases intraoperatively.

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Titel: Development and evaluation of a prototype detector for an intraoperative laparoscopic coincidence imaging system with PET tracers
verfasst von: Madhushanka R. Liyanaarachchi
Kenji Shimazoe
Hiroyuki Takahashi
Keiichi Nakagawa
Etsuko Kobayashi
Ichiro Sakuma
Publikationsdatum: 07.11.2020
Verlag: Springer International Publishing
Erschienen in: International Journal of Computer Assisted Radiology and Surgery / Ausgabe 1/2021
Print ISSN: 1861-6410
Elektronische ISSN: 1861-6429
DOI: https://doi.org/10.1007/s11548-020-02282-0

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Development and evaluation of a prototype detector for an intraoperative laparoscopic coincidence imaging system with PET tracers

Abstract

Purpose

Methods

Results

Conclusion

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

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Purpose

Methods

Results

Conclusion

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