Skip to main content
Erschienen in: Japanese Journal of Radiology 5/2012

01.06.2012 | Original Article

Mycobacterium kansasii pulmonary infection: CT findings in 29 cases

verfasst von: Masashi Takahashi, Hiroaki Tsukamoto, Tetsuji Kawamura, Yoshirou Mochizuki, Masatsugu Ouchi, Shuhei Inoue, Norihisa Nitta, Kiyoshi Murata

Erschienen in: Japanese Journal of Radiology | Ausgabe 5/2012

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Our aim was to assess computed tomography (CT) features of Mycobacterium kansasii pulmonary infection (M. kansasii infection).

Materials and methods

A total of 29 cases confirmed to have M. kansasii infections were analyzed. The main locations of pulmonary changes, incidence, and various imaging features of the cavity (location, maximum diameter, wall thickness, satellite nodules, intracavitary fluid), and other imaging findings such as nodules, consolidation, and bronchiectasis, were visually assessed on CT images.

Results

Locations of the main abnormalities were as follows: right S2 41%; right S1 31%; left S1+S2 2: 21%. A total of 49 cavities were observed in 24 (83%) cases. The mean maximum diameter, wall thickness, and ratio of wall thickness to the maximum diameter were 33.0 mm, 4.7 mm, and 0.19, respectively. Shapes of the cavities were round in nine (18.4%), oval in 17 (34.7%), and tubular/meandering in 23 (47%). Satellite nodules were found in only 30.6% of patients (n = 15). Small nodules were found in 26 (89.7%) patients, and most of them showed a centrilobular distribution.

Conclusion

The characteristic CT findings suggestive of M. kansasii infection include cavities located in the right posterior or apical segment with a tubular/meandering shape and a thin wall.
Literatur
1.
Zurück zum Zitat Taillard C, Greub G, Weber R, Pfyffer GE, Bodmer T, Zimmerli S, et al. Clinical implications of Mycobacterium kansasii species heterogeneity: Swiss National Survey. J Clin Microbiol. 2003;41(3):1240–4.PubMedCrossRef Taillard C, Greub G, Weber R, Pfyffer GE, Bodmer T, Zimmerli S, et al. Clinical implications of Mycobacterium kansasii species heterogeneity: Swiss National Survey. J Clin Microbiol. 2003;41(3):1240–4.PubMedCrossRef
2.
Zurück zum Zitat Maliwan N, Zvetina JR. Clinical features and follow up of 302 patients with Mycobacterium kansasii pulmonary infection: a 50 year experience. Postgrad Med J. 2005;81(958):530–3.PubMedCrossRef Maliwan N, Zvetina JR. Clinical features and follow up of 302 patients with Mycobacterium kansasii pulmonary infection: a 50 year experience. Postgrad Med J. 2005;81(958):530–3.PubMedCrossRef
3.
Zurück zum Zitat Shitrit D, Priess R, Peled N, Bishara G, Shlomi D, Kramer MR. Differentiation of Mycobacterium kansasii infection from Mycobacterium tuberculosis infection: comparison of clinical features, radiological appearance, and outcome. Eur J Clin Microbiol Infect Dis. 2007;26(10):679–84.PubMedCrossRef Shitrit D, Priess R, Peled N, Bishara G, Shlomi D, Kramer MR. Differentiation of Mycobacterium kansasii infection from Mycobacterium tuberculosis infection: comparison of clinical features, radiological appearance, and outcome. Eur J Clin Microbiol Infect Dis. 2007;26(10):679–84.PubMedCrossRef
4.
Zurück zum Zitat Shitrit D, Baum GL, Priess R, Lavy A, Shitrit AB, Raz M, et al. Pulmonary Mycobacterium kansasii infection in Israel, 1999–2004: clinical features, drug susceptibility, and outcome. Chest. 2006;129(3):771–6.PubMedCrossRef Shitrit D, Baum GL, Priess R, Lavy A, Shitrit AB, Raz M, et al. Pulmonary Mycobacterium kansasii infection in Israel, 1999–2004: clinical features, drug susceptibility, and outcome. Chest. 2006;129(3):771–6.PubMedCrossRef
5.
Zurück zum Zitat Griffith DE. Management of disease due to Mycobacterium kansasii. Clin Chest Med. 2002;23(3):613–21, vi. Griffith DE. Management of disease due to Mycobacterium kansasii. Clin Chest Med. 2002;23(3):613–21, vi.
6.
Zurück zum Zitat Christensen EE, Dietz GW, Ahn CH, Chapman JS, Murry RC, Hurst GA. Radiographic manifestations of pulmonary Mycobacterium kansasii infections. AJR Am J Roentgenol. 1978;131(6):985–93.PubMed Christensen EE, Dietz GW, Ahn CH, Chapman JS, Murry RC, Hurst GA. Radiographic manifestations of pulmonary Mycobacterium kansasii infections. AJR Am J Roentgenol. 1978;131(6):985–93.PubMed
7.
Zurück zum Zitat Evans AJ, Crisp AJ, Hubbard RB, Colville A, Evans SA, Johnston ID. Pulmonary Mycobacterium kansasii infection: comparison of radiological appearances with pulmonary tuberculosis. Thorax. 1996;51(12):1243–7.PubMedCrossRef Evans AJ, Crisp AJ, Hubbard RB, Colville A, Evans SA, Johnston ID. Pulmonary Mycobacterium kansasii infection: comparison of radiological appearances with pulmonary tuberculosis. Thorax. 1996;51(12):1243–7.PubMedCrossRef
8.
Zurück zum Zitat Shitrit D, Peled N, Bishara J, Priess R, Pitlik S, Samra Z, et al. Clinical and radiological features of Mycobacterium kansasii infection and Mycobacterium simiae infection. Respir Med. 2008;102(11):1598–603.PubMedCrossRef Shitrit D, Peled N, Bishara J, Priess R, Pitlik S, Samra Z, et al. Clinical and radiological features of Mycobacterium kansasii infection and Mycobacterium simiae infection. Respir Med. 2008;102(11):1598–603.PubMedCrossRef
9.
Zurück zum Zitat Zvetina JR, Demos TC, Maliwan N, Van Drunen M, Frederick W, Lentino J, et al. Pulmonary cavitations in Mycobacterium kansasii: distinctions from M. tuberculosis. AJR Am J Roentgenol. 1984;143(1):127–30.PubMed Zvetina JR, Demos TC, Maliwan N, Van Drunen M, Frederick W, Lentino J, et al. Pulmonary cavitations in Mycobacterium kansasii: distinctions from M. tuberculosis. AJR Am J Roentgenol. 1984;143(1):127–30.PubMed
10.
Zurück zum Zitat Hollings NP, Wells AU, Wilson R, Hansell DM. Comparative appearances of non-tuberculous mycobacteria species: a CT study. Eur Radiol. 2002;12(9):2211–7.PubMed Hollings NP, Wells AU, Wilson R, Hansell DM. Comparative appearances of non-tuberculous mycobacteria species: a CT study. Eur Radiol. 2002;12(9):2211–7.PubMed
11.
Zurück zum Zitat Okada F, Ando Y, Yoshitake S, Ono A, Tanoue S, Matsumoto S, et al. Clinical/pathologic correlations in 553 patients with primary centrilobular findings on high-resolution CT scan of the thorax. Chest. 2007;132(6):1939–48.PubMedCrossRef Okada F, Ando Y, Yoshitake S, Ono A, Tanoue S, Matsumoto S, et al. Clinical/pathologic correlations in 553 patients with primary centrilobular findings on high-resolution CT scan of the thorax. Chest. 2007;132(6):1939–48.PubMedCrossRef
12.
Zurück zum Zitat Guideline for the diagnosis of pulmonary nontuberculous mycobacterial diseases—2008. The Nontuberculous Mycobacteriosis Control Committee of the Japanese Society for Tuberculosis, The Scientific Assembly for Infection and Tuberculosis of the Japanese Respiratory Society. Kekkaku. 2011;86(1):37–9. Guideline for the diagnosis of pulmonary nontuberculous mycobacterial diseases—2008. The Nontuberculous Mycobacteriosis Control Committee of the Japanese Society for Tuberculosis, The Scientific Assembly for Infection and Tuberculosis of the Japanese Respiratory Society. Kekkaku. 2011;86(1):37–9.
13.
Zurück zum Zitat Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007;175(4):367–416.PubMedCrossRef Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007;175(4):367–416.PubMedCrossRef
14.
Zurück zum Zitat Goddard PR, Nicholson EM, Laszlo G, Watt I. Computed tomography in pulmonary emphysema. Clin Radiol. 1982;33(4):379–87.PubMedCrossRef Goddard PR, Nicholson EM, Laszlo G, Watt I. Computed tomography in pulmonary emphysema. Clin Radiol. 1982;33(4):379–87.PubMedCrossRef
15.
Zurück zum Zitat Gurney JW, Schroeder BA. Upper lobe lung disease: physiologic correlates. Review. Radiology. 1988;167(2):359–66.PubMed Gurney JW, Schroeder BA. Upper lobe lung disease: physiologic correlates. Review. Radiology. 1988;167(2):359–66.PubMed
16.
Zurück zum Zitat Park HK, Koh WJ, Shim TS, Kwon OJ. Clinical characteristics and treatment outcomes of Mycobacterium kansasii lung disease in Korea. Yonsei Med J. 2010;51(4):552–6.PubMedCrossRef Park HK, Koh WJ, Shim TS, Kwon OJ. Clinical characteristics and treatment outcomes of Mycobacterium kansasii lung disease in Korea. Yonsei Med J. 2010;51(4):552–6.PubMedCrossRef
17.
Zurück zum Zitat Kim TS, Koh WJ, Han J, Chung MJ, Lee JH, Lee KS, et al. Hypothesis on the evolution of cavitary lesions in nontuberculous mycobacterial pulmonary infection: thin-section CT and histopathologic correlation. AJR Am J Roentgenol. 2005;184(4):1247–52.PubMed Kim TS, Koh WJ, Han J, Chung MJ, Lee JH, Lee KS, et al. Hypothesis on the evolution of cavitary lesions in nontuberculous mycobacterial pulmonary infection: thin-section CT and histopathologic correlation. AJR Am J Roentgenol. 2005;184(4):1247–52.PubMed
18.
Zurück zum Zitat Gorse GJ, Fairshter RD, Friedly G, Delamaza L, Greene GR, Cesario TC. Nontuberculous mycobacterial disease. Experience in a southern California hospital. Arch Intern Med. 1983;143(2):225–8.PubMedCrossRef Gorse GJ, Fairshter RD, Friedly G, Delamaza L, Greene GR, Cesario TC. Nontuberculous mycobacterial disease. Experience in a southern California hospital. Arch Intern Med. 1983;143(2):225–8.PubMedCrossRef
19.
Zurück zum Zitat Ahn CH, Wallace RJ, Steele LC, Murphy DT. Sulfonamide-containing regimens for disease caused by rifampin-resistant Mycobacterium kansasii. Am Rev Respir Dis. 1987;135(1):10–6.PubMed Ahn CH, Wallace RJ, Steele LC, Murphy DT. Sulfonamide-containing regimens for disease caused by rifampin-resistant Mycobacterium kansasii. Am Rev Respir Dis. 1987;135(1):10–6.PubMed
Metadaten
Titel
Mycobacterium kansasii pulmonary infection: CT findings in 29 cases
verfasst von
Masashi Takahashi
Hiroaki Tsukamoto
Tetsuji Kawamura
Yoshirou Mochizuki
Masatsugu Ouchi
Shuhei Inoue
Norihisa Nitta
Kiyoshi Murata
Publikationsdatum
01.06.2012
Verlag
Springer Japan
Erschienen in
Japanese Journal of Radiology / Ausgabe 5/2012
Print ISSN: 1867-1071
Elektronische ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-012-0061-z

Weitere Artikel der Ausgabe 5/2012

Japanese Journal of Radiology 5/2012 Zur Ausgabe

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.