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Erschienen in: Japanese Journal of Radiology 12/2016

28.10.2016 | Original Article

Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in ischemia-causing coronary stenosis: a meta-analysis

verfasst von: Aimin Ding, Guoqing Qiu, Wensheng Lin, Ling Hu, Guangliang Lu, Xiang Long, Xin Hong, Yaohua Chen, Xiaoping Luo, Qinqin Tang, Dongqin Deng

Erschienen in: Japanese Journal of Radiology | Ausgabe 12/2016

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Abstract

Purpose

Fractional flow reserve based on coronary computed tomographic angiography (CCTA; FFRCT) can evaluate functional severity in coronary artery disease (CAD). This study investigated the diagnostic value of FFRCT for determining CAD severity.

Materials and methods

Medline, Cochrane, EMBASE, and Google Scholar databases were searched until June 16, 2016 using the following search terms: fractional flow reserve, coronary computed tomography angiography, myocardial ischemia. Randomized controlled trials, two-arm prospective studies, and retrospective studies were included in the analysis.

Results

Twenty-one studies were included with a total of 2216 subjects and 2798 vessels. FFRCT, sensitivity per-vessel and per-patient were ≥82% and specificity was ≥73% for diagnosis of ischemia. FFRCT had better diagnostic accuracy and discrimination than CCTA.

Conclusion

This study indicates that FFRCT may be a good tool for screening and diagnosing of myocardial ischemia in patients with CAD.
Literatur
1.
Zurück zum Zitat Norgaard BL, Leipsic J, Gaur S, Seneviratne S, Ko BS, Ito H, et al. Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in suspected coronary artery disease: the NXT trial (analysis of coronary blood flow using CT angiography: next steps). J Am Coll Cardiol. 2014;63:1145–55.CrossRefPubMed Norgaard BL, Leipsic J, Gaur S, Seneviratne S, Ko BS, Ito H, et al. Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in suspected coronary artery disease: the NXT trial (analysis of coronary blood flow using CT angiography: next steps). J Am Coll Cardiol. 2014;63:1145–55.CrossRefPubMed
2.
Zurück zum Zitat Coenen A, Lubbers MM, Kurata A, Kono A, Dedic A, Chelu RG, et al. Fractional flow reserve computed from noninvasive CT angiography data: diagnostic performance of an on-site clinician-operated computational fluid dynamics algorithm. Radiology. 2015;274:674–83.CrossRefPubMed Coenen A, Lubbers MM, Kurata A, Kono A, Dedic A, Chelu RG, et al. Fractional flow reserve computed from noninvasive CT angiography data: diagnostic performance of an on-site clinician-operated computational fluid dynamics algorithm. Radiology. 2015;274:674–83.CrossRefPubMed
3.
Zurück zum Zitat Min JK, Shaw LJ, Berman DS. The present state of coronary computed tomography angiography a process in evolution. J Am Coll Cardiol. 2010;55:957–65.CrossRefPubMed Min JK, Shaw LJ, Berman DS. The present state of coronary computed tomography angiography a process in evolution. J Am Coll Cardiol. 2010;55:957–65.CrossRefPubMed
4.
Zurück zum Zitat di Cesare E, Carbone I, Carriero A, Centonze M, De Cobelli F, De Rosa R, et al. Clinical indications for cardiac computed tomography. From the Working Group of the Cardiac Radiology Section of the Italian Society of Medical Radiology (SIRM). Radiol Med. 2012;117:901–38.CrossRefPubMed di Cesare E, Carbone I, Carriero A, Centonze M, De Cobelli F, De Rosa R, et al. Clinical indications for cardiac computed tomography. From the Working Group of the Cardiac Radiology Section of the Italian Society of Medical Radiology (SIRM). Radiol Med. 2012;117:901–38.CrossRefPubMed
5.
Zurück zum Zitat Cademartiri F, Di Cesare E, Francone M, Ballerini G, Ligabue G, Maffei E, et al. Italian registry of cardiac computed tomography. Radiol Med. 2015;120:919–29.CrossRefPubMed Cademartiri F, Di Cesare E, Francone M, Ballerini G, Ligabue G, Maffei E, et al. Italian registry of cardiac computed tomography. Radiol Med. 2015;120:919–29.CrossRefPubMed
7.
Zurück zum Zitat Tonino PA, Fearon WF, De Bruyne B, Oldroyd KG, Leesar MA, Ver Lee PN, et al. Angiographic versus functional severity of coronary artery stenoses in the FAME study fractional flow reserve versus angiography in multivessel evaluation. J Am Coll Cardiol. 2010;55:2816–21.CrossRefPubMed Tonino PA, Fearon WF, De Bruyne B, Oldroyd KG, Leesar MA, Ver Lee PN, et al. Angiographic versus functional severity of coronary artery stenoses in the FAME study fractional flow reserve versus angiography in multivessel evaluation. J Am Coll Cardiol. 2010;55:2816–21.CrossRefPubMed
8.
Zurück zum Zitat De Bruyne B, Hersbach F, Pijls NH, Bartunek J, Bech JW, Heyndrickx GR, et al. Abnormal epicardial coronary resistance in patients with diffuse atherosclerosis but “Normal” coronary angiography. Circulation. 2001;104:2401–6.CrossRefPubMed De Bruyne B, Hersbach F, Pijls NH, Bartunek J, Bech JW, Heyndrickx GR, et al. Abnormal epicardial coronary resistance in patients with diffuse atherosclerosis but “Normal” coronary angiography. Circulation. 2001;104:2401–6.CrossRefPubMed
9.
Zurück zum Zitat Pijls NH, De Bruyne B, Peels K, Van Der Voort PH, Bonnier HJ, Bartunek JKJJ, et al. Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses. N Engl J Med. 1996;334:1703–8.CrossRefPubMed Pijls NH, De Bruyne B, Peels K, Van Der Voort PH, Bonnier HJ, Bartunek JKJJ, et al. Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses. N Engl J Med. 1996;334:1703–8.CrossRefPubMed
10.
Zurück zum Zitat De Bruyne B, Pijls NH, Kalesan B, Barbato E, Tonino PA, Piroth Z, et al. Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease. N Engl J Med. 2012;367:991–1001.CrossRefPubMed De Bruyne B, Pijls NH, Kalesan B, Barbato E, Tonino PA, Piroth Z, et al. Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease. N Engl J Med. 2012;367:991–1001.CrossRefPubMed
11.
Zurück zum Zitat Task Force M, Montalescot G, Sechtem U, Achenbach S, Andreotti F, Arden C, et al. 2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J. 2013;34:2949–3003.CrossRef Task Force M, Montalescot G, Sechtem U, Achenbach S, Andreotti F, Arden C, et al. 2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J. 2013;34:2949–3003.CrossRef
12.
Zurück zum Zitat Muller O, Mangiacapra F, Ntalianis A, Verhamme KM, Trana C, Hamilos M, et al. Long-term follow-up after fractional flow reserve-guided treatment strategy in patients with an isolated proximal left anterior descending coronary artery stenosis. JACC Cardiovasc Interv. 2011;4:1175–82.CrossRefPubMed Muller O, Mangiacapra F, Ntalianis A, Verhamme KM, Trana C, Hamilos M, et al. Long-term follow-up after fractional flow reserve-guided treatment strategy in patients with an isolated proximal left anterior descending coronary artery stenosis. JACC Cardiovasc Interv. 2011;4:1175–82.CrossRefPubMed
13.
Zurück zum Zitat Taylor CA, Fonte TA, Min JK. Computational fluid dynamics applied to cardiac computed tomography for noninvasive quantification of fractional flow reserve: scientific basis. J Am Coll Cardiol. 2013;61:2233–41.CrossRefPubMed Taylor CA, Fonte TA, Min JK. Computational fluid dynamics applied to cardiac computed tomography for noninvasive quantification of fractional flow reserve: scientific basis. J Am Coll Cardiol. 2013;61:2233–41.CrossRefPubMed
14.
Zurück zum Zitat Koo BK, Erglis A, Doh JH, Daniels DV, Jegere S, Kim HS, et al. Diagnosis of ischemia-causing coronary stenoses by noninvasive fractional flow reserve computed from coronary computed tomographic angiograms. Results from the prospective multicenter DISCOVER-FLOW (Diagnosis of Ischemia-Causing Stenoses Obtained Via Noninvasive Fractional Flow Reserve) study. J Am Coll Cardiol. 2011;58:1989–97.CrossRefPubMed Koo BK, Erglis A, Doh JH, Daniels DV, Jegere S, Kim HS, et al. Diagnosis of ischemia-causing coronary stenoses by noninvasive fractional flow reserve computed from coronary computed tomographic angiograms. Results from the prospective multicenter DISCOVER-FLOW (Diagnosis of Ischemia-Causing Stenoses Obtained Via Noninvasive Fractional Flow Reserve) study. J Am Coll Cardiol. 2011;58:1989–97.CrossRefPubMed
15.
Zurück zum Zitat Min JK, Leipsic J, Pencina MJ, Berman DS, Koo BK, van Mieghem C, et al. Diagnostic accuracy of fractional flow reserve from anatomic CT angiography. JAMA. 2012;308:1237–45.CrossRefPubMedPubMedCentral Min JK, Leipsic J, Pencina MJ, Berman DS, Koo BK, van Mieghem C, et al. Diagnostic accuracy of fractional flow reserve from anatomic CT angiography. JAMA. 2012;308:1237–45.CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, et al. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011;155:529–36.CrossRefPubMed Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, et al. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011;155:529–36.CrossRefPubMed
18.
Zurück zum Zitat Tesche C, De Cecco CN, Caruso D, Baumann S, Renker M, Mangold S, et al. Coronary CT angiography derived morphological and functional quantitative plaque markers correlated with invasive fractional flow reserve for detecting hemodynamically significant stenosis. J Cardiovasc Comput Tomogr. 2016;10:199–206.CrossRefPubMed Tesche C, De Cecco CN, Caruso D, Baumann S, Renker M, Mangold S, et al. Coronary CT angiography derived morphological and functional quantitative plaque markers correlated with invasive fractional flow reserve for detecting hemodynamically significant stenosis. J Cardiovasc Comput Tomogr. 2016;10:199–206.CrossRefPubMed
19.
Zurück zum Zitat Meijboom WB, Van Mieghem CA, van Pelt N, Weustink A, Pugliese F, Mollet NR, et al. Comprehensive assessment of coronary artery stenoses: computed tomography coronary angiography versus conventional coronary angiography and correlation with fractional flow reserve in patients with stable angina. J Am Coll Cardiol. 2008;52:636–43.CrossRefPubMed Meijboom WB, Van Mieghem CA, van Pelt N, Weustink A, Pugliese F, Mollet NR, et al. Comprehensive assessment of coronary artery stenoses: computed tomography coronary angiography versus conventional coronary angiography and correlation with fractional flow reserve in patients with stable angina. J Am Coll Cardiol. 2008;52:636–43.CrossRefPubMed
20.
Zurück zum Zitat Rossi A, Dharampal A, Wragg A, Davies LC, van Geuns RJ, Anagnostopoulos C, et al. Diagnostic performance of hyperaemic myocardial blood flow index obtained by dynamic computed tomography: does it predict functionally significant coronary lesions? Eur Heart J Cardiovasc Imaging. 2014;15:85–94.CrossRefPubMed Rossi A, Dharampal A, Wragg A, Davies LC, van Geuns RJ, Anagnostopoulos C, et al. Diagnostic performance of hyperaemic myocardial blood flow index obtained by dynamic computed tomography: does it predict functionally significant coronary lesions? Eur Heart J Cardiovasc Imaging. 2014;15:85–94.CrossRefPubMed
21.
Zurück zum Zitat Choo KS, Hwangbo L, Kim JH, Park YH, Kim JS, Kim J, et al. Adenosine-stress low-dose single-scan CT myocardial perfusion imaging using a 128-slice dual-source CT: a comparison with fractional flow reserve. Acta Radiol. 2013;54:389–95.CrossRefPubMed Choo KS, Hwangbo L, Kim JH, Park YH, Kim JS, Kim J, et al. Adenosine-stress low-dose single-scan CT myocardial perfusion imaging using a 128-slice dual-source CT: a comparison with fractional flow reserve. Acta Radiol. 2013;54:389–95.CrossRefPubMed
22.
Zurück zum Zitat Kristensen TS, Engstrom T, Kelbaek H, von der Recke P, Nielsen MB, Kofoed KF. Correlation between coronary computed tomographic angiography and fractional flow reserve. Int J Cardiol. 2010;144:200–5.CrossRefPubMed Kristensen TS, Engstrom T, Kelbaek H, von der Recke P, Nielsen MB, Kofoed KF. Correlation between coronary computed tomographic angiography and fractional flow reserve. Int J Cardiol. 2010;144:200–5.CrossRefPubMed
23.
Zurück zum Zitat Stuijfzand WJ, Danad I, Raijmakers PG, Marcu CB, Heymans MW, van Kuijk CC, et al. Additional value of transluminal attenuation gradient in CT angiography to predict hemodynamic significance of coronary artery stenosis. JACC Cardiovasc Imaging. 2014;7:374–86.CrossRefPubMedPubMedCentral Stuijfzand WJ, Danad I, Raijmakers PG, Marcu CB, Heymans MW, van Kuijk CC, et al. Additional value of transluminal attenuation gradient in CT angiography to predict hemodynamic significance of coronary artery stenosis. JACC Cardiovasc Imaging. 2014;7:374–86.CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Voros S, Rinehart S, Vazquez-Figueroa JG, Kalynych A, Karmpaliotis D, Qian Z, et al. Prospective, head-to-head comparison of quantitative coronary angiography, quantitative computed tomography angiography, and intravascular ultrasound for the prediction of hemodynamic significance in intermediate and severe lesions, using fractional flow reserve as reference standard (from the ATLANTA I and II Study). Am J Cardiol. 2014;113:23–9.CrossRefPubMed Voros S, Rinehart S, Vazquez-Figueroa JG, Kalynych A, Karmpaliotis D, Qian Z, et al. Prospective, head-to-head comparison of quantitative coronary angiography, quantitative computed tomography angiography, and intravascular ultrasound for the prediction of hemodynamic significance in intermediate and severe lesions, using fractional flow reserve as reference standard (from the ATLANTA I and II Study). Am J Cardiol. 2014;113:23–9.CrossRefPubMed
25.
Zurück zum Zitat Dai N, Lv HJ, Xiang YF, Fan B, Li WM, Xu YW. Three-dimensional modeling and numerical analysis of fractional flow reserve in human coronary arteries. Postepy Kardiol Interwencyjnej. 2016;12:25–31.PubMedPubMedCentral Dai N, Lv HJ, Xiang YF, Fan B, Li WM, Xu YW. Three-dimensional modeling and numerical analysis of fractional flow reserve in human coronary arteries. Postepy Kardiol Interwencyjnej. 2016;12:25–31.PubMedPubMedCentral
26.
Zurück zum Zitat Wong DT, Ko BS, Cameron JD, Nerlekar N, Leung MC, Malaiapan Y, et al. Transluminal attenuation gradient in coronary computed tomography angiography is a novel noninvasive approach to the identification of functionally significant coronary artery stenosis: a comparison with fractional flow reserve. J Am Coll Cardiol. 2013;61:1271–9.CrossRefPubMed Wong DT, Ko BS, Cameron JD, Nerlekar N, Leung MC, Malaiapan Y, et al. Transluminal attenuation gradient in coronary computed tomography angiography is a novel noninvasive approach to the identification of functionally significant coronary artery stenosis: a comparison with fractional flow reserve. J Am Coll Cardiol. 2013;61:1271–9.CrossRefPubMed
27.
Zurück zum Zitat Osawa K, Miyoshi T, Miki T, Koyama Y, Sato S, Kanazawa S, et al. Diagnostic performance of first-pass myocardial perfusion imaging without stress with computed tomography (CT) compared with coronary CT angiography alone, with fractional flow reserve as the reference standard. PLoS One. 2016;11:e0149170.CrossRefPubMedPubMedCentral Osawa K, Miyoshi T, Miki T, Koyama Y, Sato S, Kanazawa S, et al. Diagnostic performance of first-pass myocardial perfusion imaging without stress with computed tomography (CT) compared with coronary CT angiography alone, with fractional flow reserve as the reference standard. PLoS One. 2016;11:e0149170.CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat Neglia D, Rovai D, Caselli C, Pietila M, Teresinska A, Aguade-Bruix S, et al. Detection of significant coronary artery disease by noninvasive anatomical and functional imaging. Circ Cardiovasc Imaging. 2015;. doi:10.1161/CIRCIMAGING.114.002179.PubMed Neglia D, Rovai D, Caselli C, Pietila M, Teresinska A, Aguade-Bruix S, et al. Detection of significant coronary artery disease by noninvasive anatomical and functional imaging. Circ Cardiovasc Imaging. 2015;. doi:10.​1161/​CIRCIMAGING.​114.​002179.PubMed
29.
Zurück zum Zitat Renker M, Schoepf UJ, Wang R, Meinel FG, Rier JD, Bayer RR 2nd, et al. Comparison of diagnostic value of a novel noninvasive coronary computed tomography angiography method versus standard coronary angiography for assessing fractional flow reserve. Am J Cardiol. 2014;114:1303–8.CrossRefPubMed Renker M, Schoepf UJ, Wang R, Meinel FG, Rier JD, Bayer RR 2nd, et al. Comparison of diagnostic value of a novel noninvasive coronary computed tomography angiography method versus standard coronary angiography for assessing fractional flow reserve. Am J Cardiol. 2014;114:1303–8.CrossRefPubMed
30.
Zurück zum Zitat Choi JH, Koo BK, Yoon YE, Min JK, Song YB, Hahn JY, et al. Diagnostic performance of intracoronary gradient-based methods by coronary computed tomography angiography for the evaluation of physiologically significant coronary artery stenoses: a validation study with fractional flow reserve. Eur Heart J Cardiovasc Imaging. 2012;13:1001–7.CrossRefPubMed Choi JH, Koo BK, Yoon YE, Min JK, Song YB, Hahn JY, et al. Diagnostic performance of intracoronary gradient-based methods by coronary computed tomography angiography for the evaluation of physiologically significant coronary artery stenoses: a validation study with fractional flow reserve. Eur Heart J Cardiovasc Imaging. 2012;13:1001–7.CrossRefPubMed
31.
Zurück zum Zitat Kim KH, Doh JH, Koo BK, Min JK, Erglis A, Yang HM, et al. A novel noninvasive technology for treatment planning using virtual coronary stenting and computed tomography-derived computed fractional flow reserve. JACC Cardiovasc Interv. 2014;7:72–8.CrossRefPubMed Kim KH, Doh JH, Koo BK, Min JK, Erglis A, Yang HM, et al. A novel noninvasive technology for treatment planning using virtual coronary stenting and computed tomography-derived computed fractional flow reserve. JACC Cardiovasc Interv. 2014;7:72–8.CrossRefPubMed
32.
Zurück zum Zitat Ko BS, Wong DT, Cameron JD, Leong DP, Leung M, Meredith IT, et al. 320-row CT coronary angiography predicts freedom from revascularisation and acts as a gatekeeper to defer invasive angiography in stable coronary artery disease: a fractional flow reserve-correlated study. Eur Radiol. 2014;24:738–47.CrossRefPubMed Ko BS, Wong DT, Cameron JD, Leong DP, Leung M, Meredith IT, et al. 320-row CT coronary angiography predicts freedom from revascularisation and acts as a gatekeeper to defer invasive angiography in stable coronary artery disease: a fractional flow reserve-correlated study. Eur Radiol. 2014;24:738–47.CrossRefPubMed
33.
Zurück zum Zitat Opolski MP, Kepka C, Achenbach S, Pregowski J, Kruk M, Staruch AD, et al. Advanced computed tomographic anatomical and morphometric plaque analysis for prediction of fractional flow reserve in intermediate coronary lesions. Eur J Radiol. 2014;83:135–41.CrossRefPubMed Opolski MP, Kepka C, Achenbach S, Pregowski J, Kruk M, Staruch AD, et al. Advanced computed tomographic anatomical and morphometric plaque analysis for prediction of fractional flow reserve in intermediate coronary lesions. Eur J Radiol. 2014;83:135–41.CrossRefPubMed
34.
Zurück zum Zitat Schaap J, Kauling RM, Boekholdt SM, Nieman K, Meijboom WB, Post MC, et al. Incremental diagnostic accuracy of hybrid SPECT/CT coronary angiography in a population with an intermediate to high pre-test likelihood of coronary artery disease. Eur Heart J Cardiovasc Imaging. 2013;14:642–9.CrossRefPubMed Schaap J, Kauling RM, Boekholdt SM, Nieman K, Meijboom WB, Post MC, et al. Incremental diagnostic accuracy of hybrid SPECT/CT coronary angiography in a population with an intermediate to high pre-test likelihood of coronary artery disease. Eur Heart J Cardiovasc Imaging. 2013;14:642–9.CrossRefPubMed
35.
Zurück zum Zitat Deng SB, Jing XD, Wang J, Huang C, Xia S, Du JL, et al. Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in coronary artery disease: A systematic review and meta-analysis. Int J Cardiol. 2015;184:703–9.CrossRefPubMed Deng SB, Jing XD, Wang J, Huang C, Xia S, Du JL, et al. Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in coronary artery disease: A systematic review and meta-analysis. Int J Cardiol. 2015;184:703–9.CrossRefPubMed
36.
Zurück zum Zitat Gonzalez JA, Lipinski MJ, Flors L, Shaw PW, Kramer CM, Salerno M. Meta-analysis of diagnostic performance of coronary computed tomography angiography, computed tomography perfusion, and computed tomography-fractional flow reserve in functional myocardial ischemia assessment versus invasive fractional flow reserve. Am J Cardiol. 2015;116:1469–78.CrossRefPubMedPubMedCentral Gonzalez JA, Lipinski MJ, Flors L, Shaw PW, Kramer CM, Salerno M. Meta-analysis of diagnostic performance of coronary computed tomography angiography, computed tomography perfusion, and computed tomography-fractional flow reserve in functional myocardial ischemia assessment versus invasive fractional flow reserve. Am J Cardiol. 2015;116:1469–78.CrossRefPubMedPubMedCentral
37.
Zurück zum Zitat Xu R, Li C, Qian J, Ge J. Computed tomography-derived fractional flow reserve in the detection of lesion-specific ischemia: an integrated analysis of 3 pivotal trials. Medicine (Baltimore). 2015;94:e1963. doi:10.1097/MD.0000000000001963.CrossRef Xu R, Li C, Qian J, Ge J. Computed tomography-derived fractional flow reserve in the detection of lesion-specific ischemia: an integrated analysis of 3 pivotal trials. Medicine (Baltimore). 2015;94:e1963. doi:10.​1097/​MD.​0000000000001963​.CrossRef
38.
Zurück zum Zitat Li S, Tang X, Peng L, Luo Y, Dong R, Liu J. The diagnostic performance of CT-derived fractional flow reserve for evaluation of myocardial ischaemia confirmed by invasive fractional flow reserve: a meta-analysis. Clin Radiol. 2015;70:476–86.CrossRefPubMed Li S, Tang X, Peng L, Luo Y, Dong R, Liu J. The diagnostic performance of CT-derived fractional flow reserve for evaluation of myocardial ischaemia confirmed by invasive fractional flow reserve: a meta-analysis. Clin Radiol. 2015;70:476–86.CrossRefPubMed
39.
Zurück zum Zitat Danad I, Szymonifka J, Twisk JW, Norgaard BL, Zarins CK, Knaapen P, et al. Diagnostic performance of cardiac imaging methods to diagnose ischaemia-causing coronary artery disease when directly compared with fractional flow reserve as a reference standard: a meta-analysis. Eur Heart J. 2016;. doi:10.1093/eurheartj/ehw095. Danad I, Szymonifka J, Twisk JW, Norgaard BL, Zarins CK, Knaapen P, et al. Diagnostic performance of cardiac imaging methods to diagnose ischaemia-causing coronary artery disease when directly compared with fractional flow reserve as a reference standard: a meta-analysis. Eur Heart J. 2016;. doi:10.​1093/​eurheartj/​ehw095.
40.
Zurück zum Zitat Wang R, Renker M, Schoepf UJ, Wichmann JL, Fuller SR, Rier JD, et al. Diagnostic value of quantitative stenosis predictors with coronary CT angiography compared to invasive fractional flow reserve. Eur J Radiol. 2015;84:1509–15.CrossRefPubMed Wang R, Renker M, Schoepf UJ, Wichmann JL, Fuller SR, Rier JD, et al. Diagnostic value of quantitative stenosis predictors with coronary CT angiography compared to invasive fractional flow reserve. Eur J Radiol. 2015;84:1509–15.CrossRefPubMed
41.
Zurück zum Zitat Nakanishi R, Matsumoto S, Alani A, Li D, Kitslaar PH, Broersen A, et al. Diagnostic performance of transluminal attenuation gradient and fractional flow reserve by coronary computed tomographic angiography (FFR(CT)) compared to invasive FFR: a sub-group analysis from the DISCOVER-FLOW and DeFACTO studies. Int J Cardiovasc Imaging. 2015;31:1251–9.CrossRefPubMed Nakanishi R, Matsumoto S, Alani A, Li D, Kitslaar PH, Broersen A, et al. Diagnostic performance of transluminal attenuation gradient and fractional flow reserve by coronary computed tomographic angiography (FFR(CT)) compared to invasive FFR: a sub-group analysis from the DISCOVER-FLOW and DeFACTO studies. Int J Cardiovasc Imaging. 2015;31:1251–9.CrossRefPubMed
42.
Zurück zum Zitat Baumann S, Wang R, Schoepf UJ, Steinberg DH, Spearman JV, Bayer RR 2nd, et al. Coronary CT angiography-derived fractional flow reserve correlated with invasive fractional flow reserve measurements—initial experience with a novel physician-driven algorithm. Eur Radiol. 2015;25:1201–7.CrossRefPubMed Baumann S, Wang R, Schoepf UJ, Steinberg DH, Spearman JV, Bayer RR 2nd, et al. Coronary CT angiography-derived fractional flow reserve correlated with invasive fractional flow reserve measurements—initial experience with a novel physician-driven algorithm. Eur Radiol. 2015;25:1201–7.CrossRefPubMed
Metadaten
Titel
Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in ischemia-causing coronary stenosis: a meta-analysis
verfasst von
Aimin Ding
Guoqing Qiu
Wensheng Lin
Ling Hu
Guangliang Lu
Xiang Long
Xin Hong
Yaohua Chen
Xiaoping Luo
Qinqin Tang
Dongqin Deng
Publikationsdatum
28.10.2016
Verlag
Springer Japan
Erschienen in
Japanese Journal of Radiology / Ausgabe 12/2016
Print ISSN: 1867-1071
Elektronische ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-016-0589-4

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