Erschienen in:
01.11.2007
A Composite Adenoendocrine Carcinoma of the Stomach Arising from a Neuroendocrine Tumor
verfasst von:
Ulrich Ronellenfitsch, Philipp Ströbel, Matthias H. M. Schwarzbach, Wilko I. Staiger, Dieter Gragert, Georg Kähler
Erschienen in:
Journal of Gastrointestinal Surgery
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Ausgabe 11/2007
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Abstract
Gastric neuroendocrine tumors (carcinoids) are relatively uncommon neoplasms. Some 70 to 80% of these lesions occur in patients with autoimmune body gastritis. This disorder, however, is also a risk factor for the development of conventional gastric adenocarcinomas. We report a case of a patient with autoimmune body gastritis and a well-differentiated neuroendocrine tumor of the stomach, which was removed with endoscopic full-thickness resection in sano upon signs of invasive growth several years after its first diagnosis. Histological examination surprisingly showed a composite glandular-endocrine gastric carcinoma. We discuss the histopathological genesis of the tumor and provide evidence that endoscopic full-thickness resection might be an oncologically appropriate minimally invasive treatment for such gastric lesions.