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Erschienen in: Journal of Gastrointestinal Surgery 1/2010

01.02.2010 | DeMeester Festschrift

Evaluation and Treatment of Superficial Esophageal Cancer

verfasst von: Steven R. DeMeester

Erschienen in: Journal of Gastrointestinal Surgery | Sonderheft 1/2010

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Abstract

Introduction

Adenocarcinoma of the esophagus is the fastest increasing cancer in the USA, and an increasing number of patients are identified with early-stage disease. The evaluation and treatment of these superficial cancers differs from local and regionally advanced lesions.

Methods

This paper is a review of the current methods to diagnose, stage, and treat superficial esophageal adenocarcinoma.

Results

Intramucosal adenocarcinoma can be effectively treated with endoscopic resection techniques and with less morbid surgical options including a vagal-sparing esophagectomy. However, submucosal lesions are associated with a significant risk for lymph node metastases and are best treated with esophagectomy and lymphadenectomy.

Discussion

There has been a major shift in the treatment for Barrett’s high-grade dysplasia and superficial esophageal adenocarcinoma in the past 10 years. New therapies minimize the morbidity and mortality of traditional forms of esophagectomy and in some cases allow esophageal preservation. Individualization of therapy will allow maximization of successful outcome and quality of life with minimization of complications and recurrence of Barrett’s or cancer.
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Metadaten
Titel
Evaluation and Treatment of Superficial Esophageal Cancer
verfasst von
Steven R. DeMeester
Publikationsdatum
01.02.2010
Verlag
Springer-Verlag
Erschienen in
Journal of Gastrointestinal Surgery / Ausgabe Sonderheft 1/2010
Print ISSN: 1091-255X
Elektronische ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-009-1025-1

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