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Erschienen in: Journal of Gastrointestinal Surgery 5/2015

01.05.2015 | Original Article

Conduit Vascular Evaluation is Associated with Reduction in Anastomotic Leak After Esophagectomy

verfasst von: Chase Campbell, Mark K. Reames, Myra Robinson, James Symanowski, Jonathan C. Salo

Erschienen in: Journal of Gastrointestinal Surgery | Ausgabe 5/2015

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Abstract

Background

Anastomotic leak following esophagectomy is associated with significant morbidity and mortality. A major factor determining anastomotic success is an adequate blood supply to the conduit. The aim of this study was to determine the impact of intraoperative evaluation of the conduit’s vascular supply on anastomotic failure after esophagectomy.

Methods

We retrospectively analyzed data from 90 consecutive patients undergoing esophagectomy with gastric conduit reconstruction. A change in surgical practice occurred after 60 cases were completed, when we introduced the use of intraoperative indocyanine green fluorescence angiography and Doppler examination to evaluate blood supply and assist in construction of the conduit. The leak rates before and after implementation of conduit vascular evaluation were compared.

Results

After the introduction of intraoperative vascular evaluation of the gastric conduit, we noted a dramatic decrease in the rate of anastomotic leak from 20 % in the first 60 patients to 0 % in the succeeding 30 patients.

Conclusions

Intraoperative vascular evaluation with indocyanine green fluorescence imaging and Doppler examination of the gastric conduit used to assist reconstruction after esophagectomy allows for enhanced construction of the conduit that maximizes blood supply to the anastomosis. This change in practice was associated with a significant reduction in anastomotic leak rate.
Literatur
1.
Zurück zum Zitat Hanna EM, Norton HJ, Reames MK, Salo JC. Minimally invasive esophagectomy in the community hospital setting. Surg Oncol Clin N Am. 2011;20(3):521–530.CrossRefPubMed Hanna EM, Norton HJ, Reames MK, Salo JC. Minimally invasive esophagectomy in the community hospital setting. Surg Oncol Clin N Am. 2011;20(3):521–530.CrossRefPubMed
2.
Zurück zum Zitat Yap CH, Colson ME, Watters DA. Cumulative sum techniques for surgeons: a brief review. ANZ J Surg. 2007;77(7):583–586.CrossRefPubMed Yap CH, Colson ME, Watters DA. Cumulative sum techniques for surgeons: a brief review. ANZ J Surg. 2007;77(7):583–586.CrossRefPubMed
3.
Zurück zum Zitat Urschel JD. Esophagogastrostomy anastomotic leaks complicating esophagectomy: a review. Am J Surg. 1995;169(6):634–640.CrossRefPubMed Urschel JD. Esophagogastrostomy anastomotic leaks complicating esophagectomy: a review. Am J Surg. 1995;169(6):634–640.CrossRefPubMed
4.
Zurück zum Zitat Alanezi K, Urschel JD. Mortality secondary to esophageal anastomotic leak. Ann Thorac Cardiovasc Surg. 2004;10(2):71–75.PubMed Alanezi K, Urschel JD. Mortality secondary to esophageal anastomotic leak. Ann Thorac Cardiovasc Surg. 2004;10(2):71–75.PubMed
5.
Zurück zum Zitat Lagarde SM, de Boer JD, ten Kate FJ, Busch OR, Obertop H, van Lanschot JJ. Postoperative complications after esophagectomy for adenocarcinoma of the esophagus are related to timing of death due to recurrence. Ann Surg. 2008;247(1):71–76.CrossRefPubMed Lagarde SM, de Boer JD, ten Kate FJ, Busch OR, Obertop H, van Lanschot JJ. Postoperative complications after esophagectomy for adenocarcinoma of the esophagus are related to timing of death due to recurrence. Ann Surg. 2008;247(1):71–76.CrossRefPubMed
6.
Zurück zum Zitat Pham TH, Perry KA, Enestvedt CK, et al. Decreased conduit perfusion measured by spectroscopy is associated with anastomotic complications. Ann Thorac Surg. 2011;91(2):380–385.CrossRefPubMed Pham TH, Perry KA, Enestvedt CK, et al. Decreased conduit perfusion measured by spectroscopy is associated with anastomotic complications. Ann Thorac Surg. 2011;91(2):380–385.CrossRefPubMed
7.
Zurück zum Zitat Liebermann-Meffert DM, Meier R, Siewert JR. Vascular anatomy of the gastric tube used for esophageal reconstruction. Ann Thorac Surg. 1992;54(6):1110–1115.CrossRefPubMed Liebermann-Meffert DM, Meier R, Siewert JR. Vascular anatomy of the gastric tube used for esophageal reconstruction. Ann Thorac Surg. 1992;54(6):1110–1115.CrossRefPubMed
8.
Zurück zum Zitat Schroder W, Stippel D, Beckurts KT, Lacher M, Gutschow C, Holscher AH. Intraoperative changes of mucosal pCO2 during gastric tube formation. Langenbecks Arch Surg. 2001;386(5):324–327.CrossRefPubMed Schroder W, Stippel D, Beckurts KT, Lacher M, Gutschow C, Holscher AH. Intraoperative changes of mucosal pCO2 during gastric tube formation. Langenbecks Arch Surg. 2001;386(5):324–327.CrossRefPubMed
9.
Zurück zum Zitat Schilling MK, Redaelli C, Maurer C, Friess H, Buchler MW. Gastric microcirculatory changes during gastric tube formation: assessment with laser Doppler flowmetry. J Surg Res. 1996;62(1):125–129.CrossRefPubMed Schilling MK, Redaelli C, Maurer C, Friess H, Buchler MW. Gastric microcirculatory changes during gastric tube formation: assessment with laser Doppler flowmetry. J Surg Res. 1996;62(1):125–129.CrossRefPubMed
10.
Zurück zum Zitat Tarui T, Murata A, Watanabe Y, et al. Earlier prediction of anastomotic insufficiency after thoracic esophagectomy by intramucosal pH. Crit Care Med. 1999;27(9):1824–1831.CrossRefPubMed Tarui T, Murata A, Watanabe Y, et al. Earlier prediction of anastomotic insufficiency after thoracic esophagectomy by intramucosal pH. Crit Care Med. 1999;27(9):1824–1831.CrossRefPubMed
11.
Zurück zum Zitat Pierie JP, De Graaf PW, Poen H, Van der Tweel I, Obertop H. Impaired healing of cervical oesophagogastrostomies can be predicted by estimation of gastric serosal blood perfusion by laser Doppler flowmetry. Eur J Surg. 1994;160(11):599–603.PubMed Pierie JP, De Graaf PW, Poen H, Van der Tweel I, Obertop H. Impaired healing of cervical oesophagogastrostomies can be predicted by estimation of gastric serosal blood perfusion by laser Doppler flowmetry. Eur J Surg. 1994;160(11):599–603.PubMed
12.
Zurück zum Zitat Bludau M, Holscher AH, Vallbohmer D, Gutschow C, Schroder W. Ischemic conditioning of the gastric conduit prior to esophagectomy improves mucosal oxygen saturation. Ann Thorac Surg. 2010;90(4):1121–1126.CrossRefPubMed Bludau M, Holscher AH, Vallbohmer D, Gutschow C, Schroder W. Ischemic conditioning of the gastric conduit prior to esophagectomy improves mucosal oxygen saturation. Ann Thorac Surg. 2010;90(4):1121–1126.CrossRefPubMed
13.
Zurück zum Zitat Wajed SA, Veeramootoo D, Shore AC. Video. Surgical optimisation of the gastric conduit for minimally invasive oesophagectomy. Surg Endosc. 2012;26(1):271–276.CrossRefPubMed Wajed SA, Veeramootoo D, Shore AC. Video. Surgical optimisation of the gastric conduit for minimally invasive oesophagectomy. Surg Endosc. 2012;26(1):271–276.CrossRefPubMed
14.
Zurück zum Zitat Veeramootoo D, Shore AC, Wajed SA. Randomized controlled trial of laparoscopic gastric ischemic conditioning prior to minimally invasive esophagectomy, the LOGIC trial. Surg Endosc. 2012;26(7):1822–1829.CrossRefPubMed Veeramootoo D, Shore AC, Wajed SA. Randomized controlled trial of laparoscopic gastric ischemic conditioning prior to minimally invasive esophagectomy, the LOGIC trial. Surg Endosc. 2012;26(7):1822–1829.CrossRefPubMed
15.
Zurück zum Zitat Nguyen NT, Nguyen XM, Reavis KM, Elliott C, Masoomi H, Stamos MJ. Minimally invasive esophagectomy with and without gastric ischemic conditioning. Surg Endosc. 2012;26(6):1637–1641.CrossRefPubMed Nguyen NT, Nguyen XM, Reavis KM, Elliott C, Masoomi H, Stamos MJ. Minimally invasive esophagectomy with and without gastric ischemic conditioning. Surg Endosc. 2012;26(6):1637–1641.CrossRefPubMed
16.
Zurück zum Zitat Phillips BT, Lanier ST, Conkling N, et al. Intraoperative perfusion techniques can accurately predict mastectomy skin flap necrosis in breast reconstruction: results of a prospective trial. Plast Reconstr Surg. 2012;129(5):778e–788e.CrossRefPubMed Phillips BT, Lanier ST, Conkling N, et al. Intraoperative perfusion techniques can accurately predict mastectomy skin flap necrosis in breast reconstruction: results of a prospective trial. Plast Reconstr Surg. 2012;129(5):778e–788e.CrossRefPubMed
17.
Zurück zum Zitat Komorowska-Timek E, Gurtner GC. Intraoperative perfusion mapping with laser-assisted indocyanine green imaging can predict and prevent complications in immediate breast reconstruction. Plast Reconstr Surg. 2010;125(4):1065–1073.CrossRefPubMed Komorowska-Timek E, Gurtner GC. Intraoperative perfusion mapping with laser-assisted indocyanine green imaging can predict and prevent complications in immediate breast reconstruction. Plast Reconstr Surg. 2010;125(4):1065–1073.CrossRefPubMed
18.
Zurück zum Zitat Kubota K, Yoshida M, Kuroda J, Okada A, Ohta K, Kitajima M. Application of the HyperEye Medical System for esophageal cancer surgery: a preliminary report. Surg Today. 2013;43(2):215–220.CrossRefPubMed Kubota K, Yoshida M, Kuroda J, Okada A, Ohta K, Kitajima M. Application of the HyperEye Medical System for esophageal cancer surgery: a preliminary report. Surg Today. 2013;43(2):215–220.CrossRefPubMed
19.
Zurück zum Zitat Pacheco PE, Hill SM, Henriques SM, Paulsen JK, Anderson RC. The novel use of intraoperative laser-induced fluorescence of indocyanine green tissue angiography for evaluation of the gastric conduit in esophageal reconstructive surgery. Am J Surg. 2013;205(3):349–352.CrossRefPubMed Pacheco PE, Hill SM, Henriques SM, Paulsen JK, Anderson RC. The novel use of intraoperative laser-induced fluorescence of indocyanine green tissue angiography for evaluation of the gastric conduit in esophageal reconstructive surgery. Am J Surg. 2013;205(3):349–352.CrossRefPubMed
20.
Zurück zum Zitat Bowles TA, Watters DA. Time to CUSUM: simplified reporting of outcomes in colorectal surgery. ANZ J Surg. 2007;77(7):587–591.CrossRefPubMed Bowles TA, Watters DA. Time to CUSUM: simplified reporting of outcomes in colorectal surgery. ANZ J Surg. 2007;77(7):587–591.CrossRefPubMed
21.
Zurück zum Zitat Rogers CA, Reeves BC, Caputo M, Ganesh JS, Bonser RS, Angelini GD. Control chart methods for monitoring cardiac surgical performance and their interpretation. J Thorac Cardiovasc Surg. 2004;128(6):811–819.CrossRefPubMed Rogers CA, Reeves BC, Caputo M, Ganesh JS, Bonser RS, Angelini GD. Control chart methods for monitoring cardiac surgical performance and their interpretation. J Thorac Cardiovasc Surg. 2004;128(6):811–819.CrossRefPubMed
22.
Zurück zum Zitat Platell C, Barwood N, Dorfmann G, Makin G. The incidence of anastomotic leaks in patients undergoing colorectal surgery. Colorectal Dis. 2007;9(1):71–79.CrossRefPubMed Platell C, Barwood N, Dorfmann G, Makin G. The incidence of anastomotic leaks in patients undergoing colorectal surgery. Colorectal Dis. 2007;9(1):71–79.CrossRefPubMed
Metadaten
Titel
Conduit Vascular Evaluation is Associated with Reduction in Anastomotic Leak After Esophagectomy
verfasst von
Chase Campbell
Mark K. Reames
Myra Robinson
James Symanowski
Jonathan C. Salo
Publikationsdatum
01.05.2015
Verlag
Springer US
Erschienen in
Journal of Gastrointestinal Surgery / Ausgabe 5/2015
Print ISSN: 1091-255X
Elektronische ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-015-2794-3

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