Skip to main content
Erschienen in: Journal of Gastrointestinal Surgery 5/2020

30.05.2019 | Original Article

Revisional Surgery in Patients with Recurrent Dysphagia after Heller Myotomy

verfasst von: Kaylee E. Smith, BS, Adham R. Saad, MD, John P. Hanna, MD, Thanh Tran, MPH, John Jacobs, MD, Joel E. Richter, MD, Vic Velanovich, MD

Erschienen in: Journal of Gastrointestinal Surgery | Ausgabe 5/2020

Einloggen, um Zugang zu erhalten

Abstract

Background

Recurrent/persistent symptoms of achalasia occur in 10–20% of individuals after Heller myotomy. The causes and treatment outcomes are ambiguous. Our aim is to assess the causes and outcomes of a multidisciplinary approach to this patient population.

Methods

All patients undergoing revisional operations after a Heller myotomy were reviewed retrospectively. Data collected: demographics, date of initial Heller myotomy, preoperative evaluation, etiology of recurrent symptoms, date of revisional operation, and surgical outcomes.

Results

A total of 34 patients underwent 37 revisional operations. Operations were tailored based on preoperative multidisciplinary evaluation. Causes of symptoms: periesophageal/perihiatal fibrosis 11 (27%), obstructing fundoplication 11 (27%), incomplete myotomy 8 (20%), progression of disease 9 (22%), and epiphrenic diverticulum 1 (2%). Operations performed: reversal/no creation of fundoplication with or without re-do myotomy 22 (59%), revision/creation of fundoplication with or without myotomy 6 (16%), and esophagectomy 9 (24%). Ten patients in the 37 operations (27%) developed postoperative complications. Of 33 patients for 36 operations with follow-up, 25 patient-operations (69%) resulted in resolution or improved dysphagia. Although there was variation in symptomatic improvement by cause and operation type, none reached statistical significance.

Conclusion

There are several causes of dysphagia after Heller myotomy and a thoughtful evaluation is required. Complication rates are higher than first-time operations. Symptomatic improvement occurs in the majority of cases, but a significant minority will have persistent dysphagia. Although an individualized approach to dysphagia after Heller myotomy may improve symptoms and passage of food, the perception of dysphagia may persist in patients.
Literatur
1.
Zurück zum Zitat Boeckxstaens GE, Zaninotto G, Richter JE. Achalasia. Lancet. 2014;383(9911):83–93.CrossRef Boeckxstaens GE, Zaninotto G, Richter JE. Achalasia. Lancet. 2014;383(9911):83–93.CrossRef
2.
Zurück zum Zitat Eckardt VF, Köhne U, Junginger T, Westermeier T. Risk factors for diagnostic delay in achalasia. Dig Dis Sci 1997;42:580–585.CrossRef Eckardt VF, Köhne U, Junginger T, Westermeier T. Risk factors for diagnostic delay in achalasia. Dig Dis Sci 1997;42:580–585.CrossRef
3.
Zurück zum Zitat Ates F, Vaezi MF. The pathogenesis and management of achalasia: current status and future directions. Gut Liver 2015;9:449–463.CrossRef Ates F, Vaezi MF. The pathogenesis and management of achalasia: current status and future directions. Gut Liver 2015;9:449–463.CrossRef
4.
Zurück zum Zitat Sadowski DC, Ackah F, Jiang B, Svenson LW. Achalasia: incidence, prevalence and survival. A population-based study. Neurogastroenterol Motil. 2010;22:256–61.CrossRef Sadowski DC, Ackah F, Jiang B, Svenson LW. Achalasia: incidence, prevalence and survival. A population-based study. Neurogastroenterol Motil. 2010;22:256–61.CrossRef
5.
Zurück zum Zitat Ross D, Richter J, Velanovich V. Health-related quality of life and physiological measurements in achalasia. Dis Esophagus 2017;30:1–5PubMed Ross D, Richter J, Velanovich V. Health-related quality of life and physiological measurements in achalasia. Dis Esophagus 2017;30:1–5PubMed
6.
Zurück zum Zitat Moonen A, Boeckxstaens G. Current diagnosis and management of achalasia. J Clin Gastroenterol 2014;48:484–490.CrossRef Moonen A, Boeckxstaens G. Current diagnosis and management of achalasia. J Clin Gastroenterol 2014;48:484–490.CrossRef
7.
Zurück zum Zitat Katilius M, Velanovich V. Heller myotomy for achalasia: Quality of life comparison of laparoscopic and open technique. JSLS 2001;5:227–231PubMedPubMedCentral Katilius M, Velanovich V. Heller myotomy for achalasia: Quality of life comparison of laparoscopic and open technique. JSLS 2001;5:227–231PubMedPubMedCentral
8.
Zurück zum Zitat Torres-Villalobos G, Coss-Adame E, Furuzawa-Carballeda J, et al. Dor vs Toupet fundoplication after laparoscopic Heller myotomy: Long-term randomized controlled trial evaluated by high-resolution manometry. J Gastrointest Surg 2018;22:13–22.CrossRef Torres-Villalobos G, Coss-Adame E, Furuzawa-Carballeda J, et al. Dor vs Toupet fundoplication after laparoscopic Heller myotomy: Long-term randomized controlled trial evaluated by high-resolution manometry. J Gastrointest Surg 2018;22:13–22.CrossRef
9.
Zurück zum Zitat Ramirez M, Patti MG. Changes in the diagnosis and treatment of achalasia. Clin Transl Gastroenterol 2015 May 21;6:e87CrossRef Ramirez M, Patti MG. Changes in the diagnosis and treatment of achalasia. Clin Transl Gastroenterol 2015 May 21;6:e87CrossRef
10.
Zurück zum Zitat Petersen RP, Pellegrini CA. Revisional surgery after Heller myotomy for esophageal achalasia. Surg Laparosc Endosc Percutan Tech 2010;20:321–325.CrossRef Petersen RP, Pellegrini CA. Revisional surgery after Heller myotomy for esophageal achalasia. Surg Laparosc Endosc Percutan Tech 2010;20:321–325.CrossRef
11.
Zurück zum Zitat Duranceau A, Liberman M, Martin J, Ferraro P. End-stage achalasia. Dis Esophogus 2012; 25:319–30.CrossRef Duranceau A, Liberman M, Martin J, Ferraro P. End-stage achalasia. Dis Esophogus 2012; 25:319–30.CrossRef
12.
Zurück zum Zitat James DR, Pukayastha S, Aziz O, et al. The feasibility, safety and outcomes of laparoscopic re-operation for achalasia. Minim Invasive Ther Allied Technol. 2012; 21:161–7.CrossRef James DR, Pukayastha S, Aziz O, et al. The feasibility, safety and outcomes of laparoscopic re-operation for achalasia. Minim Invasive Ther Allied Technol. 2012; 21:161–7.CrossRef
13.
Zurück zum Zitat Wood TW, Ross SB, Ryan CE, et al. Reoperative Heller myotomy: More pain, less gain. Am Surg 2015;81:637–645PubMed Wood TW, Ross SB, Ryan CE, et al. Reoperative Heller myotomy: More pain, less gain. Am Surg 2015;81:637–645PubMed
14.
Zurück zum Zitat de Oliveira JM, Birgisson S, Doinoff C, et al . Timed-barium swallow: a simple technique for evaluating esophageal emptying in patients with achalasia. AJR Am J Roentgenol 1997;169:473–9.CrossRef de Oliveira JM, Birgisson S, Doinoff C, et al . Timed-barium swallow: a simple technique for evaluating esophageal emptying in patients with achalasia. AJR Am J Roentgenol 1997;169:473–9.CrossRef
15.
Zurück zum Zitat Vaezi MF, Baker ME, Richter JE. Assessment of esophageal emptying post-pneumatic dilation: use of the timed-barium esophagram. Am J Gastroenterol 1999;94:1802–7.CrossRef Vaezi MF, Baker ME, Richter JE. Assessment of esophageal emptying post-pneumatic dilation: use of the timed-barium esophagram. Am J Gastroenterol 1999;94:1802–7.CrossRef
16.
Zurück zum Zitat Urbach DR, Tomlinson GA, Harnish JL, et al. A measure of disease-specific health-related quality of life for achalasia. Am J Gastroenterol 2005;100:1668–1676CrossRef Urbach DR, Tomlinson GA, Harnish JL, et al. A measure of disease-specific health-related quality of life for achalasia. Am J Gastroenterol 2005;100:1668–1676CrossRef
17.
Zurück zum Zitat Patti MC, Allaix ME. Recurrent symptoms after Heller myotomy for achalasia: Evaluation and treatment. World J Surg 2015;39:1625–1630CrossRef Patti MC, Allaix ME. Recurrent symptoms after Heller myotomy for achalasia: Evaluation and treatment. World J Surg 2015;39:1625–1630CrossRef
18.
Zurück zum Zitat Zaninotto G, Costantini M, Portale G, et al. Etiology, diagnosis and treatment of failures after laparoscopic Heller myotomy for achalasia. Ann Surg 2002;235:186–192CrossRef Zaninotto G, Costantini M, Portale G, et al. Etiology, diagnosis and treatment of failures after laparoscopic Heller myotomy for achalasia. Ann Surg 2002;235:186–192CrossRef
19.
Zurück zum Zitat Loviscek MF, Wright AS, Hinojosa MW, et al. Recurrent dysphagia after Heller myotomy: Is esophagectomy always the answer? J Am Coll Surg 2013;216:736–743CrossRef Loviscek MF, Wright AS, Hinojosa MW, et al. Recurrent dysphagia after Heller myotomy: Is esophagectomy always the answer? J Am Coll Surg 2013;216:736–743CrossRef
20.
Zurück zum Zitat Iqbal A, Tierney B, Haider M, et al. Laparoscopic re-operation for failed Heller myotomy. Dis Esophagus 2006;19:193–199CrossRef Iqbal A, Tierney B, Haider M, et al. Laparoscopic re-operation for failed Heller myotomy. Dis Esophagus 2006;19:193–199CrossRef
21.
Zurück zum Zitat Veenstra BR, Goldberg RF, Bowers SP, et al. Revisional surgery after failed esophagogastric myotomy for achalasia: Successful esophageal preservation. Surg Endosc 2016;30:1754–1761CrossRef Veenstra BR, Goldberg RF, Bowers SP, et al. Revisional surgery after failed esophagogastric myotomy for achalasia: Successful esophageal preservation. Surg Endosc 2016;30:1754–1761CrossRef
22.
Zurück zum Zitat Saleh CM, Ponds FA, Schijven MP, et al. Efficacy of pneumodilation in achalasia after failed Heller mytomy. Neurogastroenterol Motil 2016;28:1741–1746CrossRef Saleh CM, Ponds FA, Schijven MP, et al. Efficacy of pneumodilation in achalasia after failed Heller mytomy. Neurogastroenterol Motil 2016;28:1741–1746CrossRef
23.
Zurück zum Zitat Mandovra P, Kalikar V, Patel A, Patankarlev. Re-do laparoscopic Heller’s cardiomyotomy for recurrent achalasia: Is laparoscoic surgery feasible? J Laparoendosc Adv Surg Tech 2018;28:298–301 Mandovra P, Kalikar V, Patel A, Patankarlev. Re-do laparoscopic Heller’s cardiomyotomy for recurrent achalasia: Is laparoscoic surgery feasible? J Laparoendosc Adv Surg Tech 2018;28:298–301
24.
Zurück zum Zitat Watson TJ. Esophagectomy for end-stage achalasia. World J Surg 2015;39:1634–1641CrossRef Watson TJ. Esophagectomy for end-stage achalasia. World J Surg 2015;39:1634–1641CrossRef
25.
Zurück zum Zitat Aiolfi A, Asti E, Bonitta G, Bonevina L. Esophagectomy for end-stage achalasia: Systematic review and meta-analysis. World J Surg 2018;42:1469–1476CrossRef Aiolfi A, Asti E, Bonitta G, Bonevina L. Esophagectomy for end-stage achalasia: Systematic review and meta-analysis. World J Surg 2018;42:1469–1476CrossRef
26.
Zurück zum Zitat Tyberg A, Sharaiha RZ, Familiari P, et al. Per-oral endoscopic myotomy as salvation technique post-Heller: International experience. Dig Endosc 2018;30:52–56CrossRef Tyberg A, Sharaiha RZ, Familiari P, et al. Per-oral endoscopic myotomy as salvation technique post-Heller: International experience. Dig Endosc 2018;30:52–56CrossRef
27.
Zurück zum Zitat Vigneswaran Y, Yetasook AK, Zhao JC, et al. Per-oral endoscopic myotomy (POEM): Feasible as reoperation following Heller myotomy. J Gastrointest Surg 2014;18:1071–1076CrossRef Vigneswaran Y, Yetasook AK, Zhao JC, et al. Per-oral endoscopic myotomy (POEM): Feasible as reoperation following Heller myotomy. J Gastrointest Surg 2014;18:1071–1076CrossRef
28.
Zurück zum Zitat Griffiths EA, Devitt PG, Jamieson CG, et al. Laparoscopic cardioplasty for end-stage achalasia. J Gastrointest Surg 2013;17:997–1001CrossRef Griffiths EA, Devitt PG, Jamieson CG, et al. Laparoscopic cardioplasty for end-stage achalasia. J Gastrointest Surg 2013;17:997–1001CrossRef
29.
Zurück zum Zitat Slone S, Kumar A, Jacobs J, et al. Achalasia quality of life score and Eckhardt score: A comparison for the assessment of clinical improvement post treatment for achalasia. Presented at the 2019 Annual Meeting of the American Gastroenterological Association, San Diego, CA, May 18-21, 2019 Slone S, Kumar A, Jacobs J, et al. Achalasia quality of life score and Eckhardt score: A comparison for the assessment of clinical improvement post treatment for achalasia. Presented at the 2019 Annual Meeting of the American Gastroenterological Association, San Diego, CA, May 18-21, 2019
30.
Zurück zum Zitat Molena D, Mungo B, Stern M, et al. Outcomes of esophagectomy for esophageal achalasia in the United States. J Gastrointest Surg 2014;18;310–317CrossRef Molena D, Mungo B, Stern M, et al. Outcomes of esophagectomy for esophageal achalasia in the United States. J Gastrointest Surg 2014;18;310–317CrossRef
31.
Zurück zum Zitat DeHaan RK, Frelich MJ, Gould JC. Intraoperative assessment of esophagogastric junction distensibility during laparoscopic Heller myotomy. Surg Laparosc Endosc Percutan Tech 2016;26:137–140CrossRef DeHaan RK, Frelich MJ, Gould JC. Intraoperative assessment of esophagogastric junction distensibility during laparoscopic Heller myotomy. Surg Laparosc Endosc Percutan Tech 2016;26:137–140CrossRef
Metadaten
Titel
Revisional Surgery in Patients with Recurrent Dysphagia after Heller Myotomy
verfasst von
Kaylee E. Smith, BS
Adham R. Saad, MD
John P. Hanna, MD
Thanh Tran, MPH
John Jacobs, MD
Joel E. Richter, MD
Vic Velanovich, MD
Publikationsdatum
30.05.2019
Verlag
Springer US
Erschienen in
Journal of Gastrointestinal Surgery / Ausgabe 5/2020
Print ISSN: 1091-255X
Elektronische ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-019-04264-3

Weitere Artikel der Ausgabe 5/2020

Journal of Gastrointestinal Surgery 5/2020 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.