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Erschienen in: Journal of General Internal Medicine 4/2007

01.04.2007 | Original Article

Primary Care Office-based Buprenorphine Treatment: Comparison of Heroin and Prescription Opioid Dependent Patients

verfasst von: Brent A. Moore, PhD, David A. Fiellin, MD, Declan T. Barry, PhD, Lynn E. Sullivan, MD, Marek C. Chawarski, PhD, Patrick G. O’Connor, MD, MPH, Richard S. Schottenfeld, MD

Erschienen in: Journal of General Internal Medicine | Ausgabe 4/2007

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Abstract

BACKGROUND

Prescription opioid dependence is increasing, but treatment outcomes with office-based buprenorphine/naloxone among these patients have not been described.

METHODS

We compared demographic, clinical characteristics and treatment outcomes among 200 patients evaluated for entry into a trial of primary care office-based buprenorphine/naloxone treatment stratifying on those who reported exclusive heroin use (n = 124), heroin and prescription opioid use (n = 47), or only prescription opioid use (n = 29).

RESULTS

Compared to heroin-only patients, prescription-opioid-only patients were younger, had fewer years of opioid use, and less drug treatment history. They were also more likely to be white, earned more income, and were less likely to have Hepatitis C antibodies. Prescription-opioid-only patients were more likely to complete treatment (59% vs. 30%), remained in treatment longer (21.0 vs. 14.2 weeks), and had a higher percent of opioid-negative urine samples than heroin only patients (56.3% vs. 39.8%), all p values < .05. Patients who used both heroin and prescription opioids had outcomes that were intermediate between heroin-only and prescription-opioid-only patients.

CONCLUSIONS

Individuals dependent on prescription opioids have an improved treatment response to buprenorphine/naloxone maintenance in an office-based setting compared to those who exclusively or episodically use heroin.
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Metadaten
Titel
Primary Care Office-based Buprenorphine Treatment: Comparison of Heroin and Prescription Opioid Dependent Patients
verfasst von
Brent A. Moore, PhD
David A. Fiellin, MD
Declan T. Barry, PhD
Lynn E. Sullivan, MD
Marek C. Chawarski, PhD
Patrick G. O’Connor, MD, MPH
Richard S. Schottenfeld, MD
Publikationsdatum
01.04.2007
Verlag
Springer-Verlag
Erschienen in
Journal of General Internal Medicine / Ausgabe 4/2007
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-007-0129-0

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