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Erschienen in: Journal of General Internal Medicine 9/2008

01.09.2008 | Original Article

EDUC’AVK: Reduction of Oral Anticoagulant-related Adverse Events After Patient Education: A Prospective Multicenter Open Randomized Study

verfasst von: Gilles Pernod, MD PhD, José Labarère, MD PhD, Jacqueline Yver, MD, Bernadette Satger, MD, Benoit Allenet, MD PhD, Touffek Berremili, MD, Michèle Fontaine, MD, Guy Franco, MD, Jean Luc Bosson, MD PhD

Erschienen in: Journal of General Internal Medicine | Ausgabe 9/2008

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Abstract

Background

Long-term oral anticoagulation treatment is associated with potential morbidity. Insufficient patient education is linked to poorly controlled anticoagulation. However the impact of a specific educational program on anticoagulation related morbidity remains unknown.

Objective

To evaluate the effect of an oral anticoagulation patient education program in reducing both hemorrhagic and recurrent thrombotic complications.

Design/Participants

We conducted a prospective, multicenter open randomized study, comparing an interventional group who received a specific oral anticoagulation treatment educational program with a control group. Eligible patients were older than 18 and diagnosed as having deep vein thrombosis or pulmonary embolism requiring therapy with a vitamin K antagonist for 3 months or more. Our primary outcome was the occurrence of hemorrhagic or thromboembolic events.

Results

During the 3-month follow-up the main outcome criteria were observed 20 times (6.6% of patients), 5 (3.1%) in the experimental and 15 (10.6%) in the control group. Consequently, in multivariate analysis, the cumulative risk reduction in the experimental group was statistically significant (OR 0.25, 95% CI 0.1 – 0.7, p < 0.01).

Conclusions

Patient education using an educational program reduced VKA-related adverse event rates.
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Metadaten
Titel
EDUC’AVK: Reduction of Oral Anticoagulant-related Adverse Events After Patient Education: A Prospective Multicenter Open Randomized Study
verfasst von
Gilles Pernod, MD PhD
José Labarère, MD PhD
Jacqueline Yver, MD
Bernadette Satger, MD
Benoit Allenet, MD PhD
Touffek Berremili, MD
Michèle Fontaine, MD
Guy Franco, MD
Jean Luc Bosson, MD PhD
Publikationsdatum
01.09.2008
Verlag
Springer-Verlag
Erschienen in
Journal of General Internal Medicine / Ausgabe 9/2008
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-008-0690-1

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