Skip to main content
Erschienen in: Journal of General Internal Medicine 11/2008

01.11.2008 | Original Article

Posttraumatic Stress and Complicated Grief in Family Members of Patients in the Intensive Care Unit

verfasst von: Wendy G. Anderson, MD, MS, Robert M. Arnold, MD, Derek C. Angus, MD, MPH, Cindy L. Bryce, PhD

Erschienen in: Journal of General Internal Medicine | Ausgabe 11/2008

Einloggen, um Zugang zu erhalten

Abstract

Background

Family members of patients in intensive care units (ICUs) are at risk for mental health morbidity both during and after a patient’s ICU stay.

Objectives

To determine prevalences of and factors associated with anxiety, depression, posttraumatic stress and complicated grief in family members of ICU patients.

Design

Prospective, longitudinal cohort study.

Participants

Fifty family members of patients in ICUs at a large university hospital participated.

Measurements

We used the Control Preferences Scale to determine participants’ role preferences for surrogate decision-making. We used the Hospital Anxiety and Depression Scale, Impact of Event Scale, and Inventory of Complicated Grief to measure anxiety and depression (at enrollment, 1 month, 6 months), posttraumatic stress (6 months), and complicated grief (6 months).

Results

We interviewed all 50 participants at enrollment, 39 (78%) at 1 month, and 34 (68%) at 6 months. At the three time points, anxiety was present in 42% (95% CI, 29–56%), 21% (95% CI, 10–35%), and 15% (95% CI, 6–29%) of participants. Depression was present in 16% (95% CI, 8–28%), 8% (95% CI, 2–19%), and 6% (95% CI, 1–18%). At 6 months, 35% (95% CI, 21–52%) of participants had posttraumatic stress. Of the 38% who were bereaved, 46% (95% CI, 22–71%) had complicated grief. Posttraumatic stress was not more common in bereaved than nonbereaved participants, and neither posttraumatic stress nor complicated grief was associated with decision-making role preference or with anxiety or depression during the patient’s ICU stay.

Conclusions

Symptoms of anxiety and depression diminished over time, but both bereaved and nonbereaved participants had high rates of posttraumatic stress and complicated grief. Family members should be assessed for posttraumatic stress and complicated grief.
Literatur
1.
Zurück zum Zitat Pochard F, Azoulay E, Chevret S, et al. Symptoms of anxiety and depression in family members of intensive care unit patients: Ethical hypothesis regarding decision-making capacity. Crit Care Med. 2001;29:1893–1897.PubMedCrossRef Pochard F, Azoulay E, Chevret S, et al. Symptoms of anxiety and depression in family members of intensive care unit patients: Ethical hypothesis regarding decision-making capacity. Crit Care Med. 2001;29:1893–1897.PubMedCrossRef
2.
Zurück zum Zitat Pochard F, Darmon M, Fassier T, et al. Symptoms of anxiety and depression in family members of intensive care unit patients before discharge or death. A prospective multicenter study. J Crit Care. 2005;20:90–96.PubMedCrossRef Pochard F, Darmon M, Fassier T, et al. Symptoms of anxiety and depression in family members of intensive care unit patients before discharge or death. A prospective multicenter study. J Crit Care. 2005;20:90–96.PubMedCrossRef
3.
Zurück zum Zitat Azoulay E, Pochard F, Kentish-Barnes N, et al. Risk of post-traumatic stress symptoms in family members of intensive care unit patients. Am J Respir Crit Care Med. 2005;171:987–994.PubMedCrossRef Azoulay E, Pochard F, Kentish-Barnes N, et al. Risk of post-traumatic stress symptoms in family members of intensive care unit patients. Am J Respir Crit Care Med. 2005;171:987–994.PubMedCrossRef
4.
Zurück zum Zitat Jones C, Skirrow P, Griffiths RD, et al. Post-traumatic stress disorder-related symptoms in relatives of patients following intensive care. Intensive Care Med. 2004;30:456–460.PubMedCrossRef Jones C, Skirrow P, Griffiths RD, et al. Post-traumatic stress disorder-related symptoms in relatives of patients following intensive care. Intensive Care Med. 2004;30:456–460.PubMedCrossRef
5.
Zurück zum Zitat Tilden VP, Tolle SW, Nelson CA, Fields J. Family decision-making to withdraw life-sustaining treatments from hospitalized patients. Nurs Res. 2001;50:105–115.PubMedCrossRef Tilden VP, Tolle SW, Nelson CA, Fields J. Family decision-making to withdraw life-sustaining treatments from hospitalized patients. Nurs Res. 2001;50:105–115.PubMedCrossRef
6.
Zurück zum Zitat Siegel MD, Hayes E, Vanderwerker LC, Loseth DB, Prigerson HG. Psychiatric illness in the next-of-kin of patients who die in the intensive care unit. Crit Care Med. 2008;36:1722–1728.PubMedCrossRef Siegel MD, Hayes E, Vanderwerker LC, Loseth DB, Prigerson HG. Psychiatric illness in the next-of-kin of patients who die in the intensive care unit. Crit Care Med. 2008;36:1722–1728.PubMedCrossRef
7.
Zurück zum Zitat Anderson WG, Arnold RM, Angus DC, Bryce CL. Passive decision-making preference is associated with anxiety and depression in relatives of patients in the intensive care unit. Journal of Critical Care. in press Anderson WG, Arnold RM, Angus DC, Bryce CL. Passive decision-making preference is associated with anxiety and depression in relatives of patients in the intensive care unit. Journal of Critical Care. in press
8.
Zurück zum Zitat Degner LF, Sloan JA. decision-making during serious illness: what role do patients really want to play? J Clin Epidemiol. 1992;45:941–950.PubMedCrossRef Degner LF, Sloan JA. decision-making during serious illness: what role do patients really want to play? J Clin Epidemiol. 1992;45:941–950.PubMedCrossRef
9.
Zurück zum Zitat Degner LF, Sloan JA, Venkatesh P. The control preferences scale. Can J Nurs Res. 1997;29:21–43.PubMed Degner LF, Sloan JA, Venkatesh P. The control preferences scale. Can J Nurs Res. 1997;29:21–43.PubMed
10.
Zurück zum Zitat Heyland DK, Rocker GM, O’Callaghan CJ, Dodek PM, Cook DJ. Dying in the ICU: Perspectives of family members. Chest. 2003;124:392–397.PubMedCrossRef Heyland DK, Rocker GM, O’Callaghan CJ, Dodek PM, Cook DJ. Dying in the ICU: Perspectives of family members. Chest. 2003;124:392–397.PubMedCrossRef
11.
Zurück zum Zitat Heyland DK, Cook DJ, Rocker GM, et al. Decision-making in the ICU: perspectives of the substitute decision-maker. Intensive Care Med. 2003;29:75–82.PubMed Heyland DK, Cook DJ, Rocker GM, et al. Decision-making in the ICU: perspectives of the substitute decision-maker. Intensive Care Med. 2003;29:75–82.PubMed
12.
Zurück zum Zitat Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361–370.PubMedCrossRef Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361–370.PubMedCrossRef
13.
Zurück zum Zitat Herrmann C. International experiences with the Hospital Anxiety and Depression Scale-A review of validation data and clinical results. J Psychosom Res. 1997;42:17–41.PubMedCrossRef Herrmann C. International experiences with the Hospital Anxiety and Depression Scale-A review of validation data and clinical results. J Psychosom Res. 1997;42:17–41.PubMedCrossRef
14.
Zurück zum Zitat Lautrette A, Darmon M, Megarbane B, et al. A communication strategy and brochure for relatives of patients dying in the ICU. N Engl J Med. 2007;356:469–478.PubMedCrossRef Lautrette A, Darmon M, Megarbane B, et al. A communication strategy and brochure for relatives of patients dying in the ICU. N Engl J Med. 2007;356:469–478.PubMedCrossRef
15.
Zurück zum Zitat Sundin EC, Horowitz MJ. Impact of Event Scale: psychometric properties. Br J Psychiatry. 2002;180:205–209.PubMedCrossRef Sundin EC, Horowitz MJ. Impact of Event Scale: psychometric properties. Br J Psychiatry. 2002;180:205–209.PubMedCrossRef
16.
Zurück zum Zitat Horowitz M, Wilner N, Alvarez W. Impact of event scale: a measure of subjective stress. Psychosom Med. 1979;41:209–218.PubMed Horowitz M, Wilner N, Alvarez W. Impact of event scale: a measure of subjective stress. Psychosom Med. 1979;41:209–218.PubMed
17.
Zurück zum Zitat Prigerson HG, Bierhals AJ, Kasl SV, et al. Complicated grief as a disorder distinct from bereavement-related depression and anxiety: a replication study. Am J Psychiatry. 1996;153:1484–1486.PubMed Prigerson HG, Bierhals AJ, Kasl SV, et al. Complicated grief as a disorder distinct from bereavement-related depression and anxiety: a replication study. Am J Psychiatry. 1996;153:1484–1486.PubMed
18.
Zurück zum Zitat Prigerson HG, Frank E, Kasl SV, et al. Complicated grief and bereavement-related depression as distinct disorders: Preliminary empirical validation in elderly bereaved spouses. Am J Psychiatry. 1995;152:22–30.PubMed Prigerson HG, Frank E, Kasl SV, et al. Complicated grief and bereavement-related depression as distinct disorders: Preliminary empirical validation in elderly bereaved spouses. Am J Psychiatry. 1995;152:22–30.PubMed
19.
Zurück zum Zitat Prigerson HG, Maciejewski PK, Reynolds CFr, et al. Inventory of complicated grief: a scale to measure maladaptive symptoms of loss. Psychiatry Res. 1995;59:65–79.PubMedCrossRef Prigerson HG, Maciejewski PK, Reynolds CFr, et al. Inventory of complicated grief: a scale to measure maladaptive symptoms of loss. Psychiatry Res. 1995;59:65–79.PubMedCrossRef
20.
Zurück zum Zitat Shear MK, Frank E, Foa E, et al. Traumatic grief treatment: a pilot study. Am J Psychiatry. 2001;158:1506–1508.PubMedCrossRef Shear MK, Frank E, Foa E, et al. Traumatic grief treatment: a pilot study. Am J Psychiatry. 2001;158:1506–1508.PubMedCrossRef
21.
Zurück zum Zitat Shear K, Frank E, Houck PR, Reynolds CF 3rd. Treatment of complicated grief: a randomized controlled trial. JAMA. 2005;293:2601–2608.PubMedCrossRef Shear K, Frank E, Houck PR, Reynolds CF 3rd. Treatment of complicated grief: a randomized controlled trial. JAMA. 2005;293:2601–2608.PubMedCrossRef
22.
Zurück zum Zitat Prigerson HG, Bridge J, Maciejewski PK, et al. Influence of traumatic grief on suicidal ideation among young adults. Am J Psychiatry. 1999;156:1994–1995.PubMed Prigerson HG, Bridge J, Maciejewski PK, et al. Influence of traumatic grief on suicidal ideation among young adults. Am J Psychiatry. 1999;156:1994–1995.PubMed
23.
Zurück zum Zitat Prigerson HG, Jacobs SC. Perspectives on care at the close of life. Caring for bereaved patients: “All the doctors just suddenly go”. JAMA. 2001;286:1369–1376.PubMedCrossRef Prigerson HG, Jacobs SC. Perspectives on care at the close of life. Caring for bereaved patients: “All the doctors just suddenly go”. JAMA. 2001;286:1369–1376.PubMedCrossRef
24.
Zurück zum Zitat Keane TM, Marshall AD, Taft CT. Posttraumatic stress disorder: etiology, epidemiology, and treatment outcome. Annu Rev Clin Psychol. 2006;2:161–197.PubMedCrossRef Keane TM, Marshall AD, Taft CT. Posttraumatic stress disorder: etiology, epidemiology, and treatment outcome. Annu Rev Clin Psychol. 2006;2:161–197.PubMedCrossRef
25.
Zurück zum Zitat Tylee A, Walters P. Underrecognition of anxiety and mood disorders in primary care: why does the problem exist and what can be done? J Clin Psychiatry. 2007;68Suppl 227–30.PubMed Tylee A, Walters P. Underrecognition of anxiety and mood disorders in primary care: why does the problem exist and what can be done? J Clin Psychiatry. 2007;68Suppl 227–30.PubMed
26.
Zurück zum Zitat Gelenberg AJ, Hopkins HS. Assessing and treating depression in primary care medicine. Am J Med. 2007;120:105–108.PubMedCrossRef Gelenberg AJ, Hopkins HS. Assessing and treating depression in primary care medicine. Am J Med. 2007;120:105–108.PubMedCrossRef
27.
Zurück zum Zitat Bobo WV, Warner CH, Warner CM. The management of post traumatic stress disorder (PTSD) in the primary care setting. South Med J. 2007;100:797–802.PubMed Bobo WV, Warner CH, Warner CM. The management of post traumatic stress disorder (PTSD) in the primary care setting. South Med J. 2007;100:797–802.PubMed
28.
Zurück zum Zitat Lichtenthal WG, Cruess DG, Prigerson HG. A case for establishing complicated grief as a distinct mental disorder in DSM-V. Clin Psychol Rev. 2004;24:637–662.PubMedCrossRef Lichtenthal WG, Cruess DG, Prigerson HG. A case for establishing complicated grief as a distinct mental disorder in DSM-V. Clin Psychol Rev. 2004;24:637–662.PubMedCrossRef
29.
Zurück zum Zitat Vanderwerker LC, Jacobs SC, Parkes CM, Prigerson HG. An exploration of associations between separation anxiety in childhood and complicated grief in later life. J Nerv Ment Dis. 2006;194:121–123.PubMedCrossRef Vanderwerker LC, Jacobs SC, Parkes CM, Prigerson HG. An exploration of associations between separation anxiety in childhood and complicated grief in later life. J Nerv Ment Dis. 2006;194:121–123.PubMedCrossRef
30.
Zurück zum Zitat Johnson JG, Vanderwerker LC, Bornstein RF, Zhang B, Prigerson HG. Development and validation of an instrument for the assessment of dependency among bereaved persons. J Psychopath Beh Ass. 2006;28:263–272. Johnson JG, Vanderwerker LC, Bornstein RF, Zhang B, Prigerson HG. Development and validation of an instrument for the assessment of dependency among bereaved persons. J Psychopath Beh Ass. 2006;28:263–272.
31.
Zurück zum Zitat Van Pelt DC, Milbrandt EB, Qin L, et al. Informal caregiver burden among survivors of prolonged mechanical ventilation. Am J Respir Crit Care Med. 2007;175:167–173.PubMedCrossRef Van Pelt DC, Milbrandt EB, Qin L, et al. Informal caregiver burden among survivors of prolonged mechanical ventilation. Am J Respir Crit Care Med. 2007;175:167–173.PubMedCrossRef
33.
Zurück zum Zitat First M, Spitzer R, Gibbon M. Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition (SCID-1/P, Version 2.0). New York: Biometrics Research Department, New York State Psychiatric Institute; 1995 First M, Spitzer R, Gibbon M. Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition (SCID-1/P, Version 2.0). New York: Biometrics Research Department, New York State Psychiatric Institute; 1995
Metadaten
Titel
Posttraumatic Stress and Complicated Grief in Family Members of Patients in the Intensive Care Unit
verfasst von
Wendy G. Anderson, MD, MS
Robert M. Arnold, MD
Derek C. Angus, MD, MPH
Cindy L. Bryce, PhD
Publikationsdatum
01.11.2008
Verlag
Springer-Verlag
Erschienen in
Journal of General Internal Medicine / Ausgabe 11/2008
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-008-0770-2

Weitere Artikel der Ausgabe 11/2008

Journal of General Internal Medicine 11/2008 Zur Ausgabe

Reflection

Radiation Room

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.