Skip to main content
Erschienen in: Obesity Surgery 7/2008

01.07.2008 | Research Article

Preoperative Weight Loss as a Predictor of Long-term Success Following Roux-en-Y Gastric Bypass

verfasst von: Sharon Alger-Mayer, John M. Polimeni, Margaret Malone

Erschienen in: Obesity Surgery | Ausgabe 7/2008

Einloggen, um Zugang zu erhalten

Abstract

Background

All patients undergoing gastric bypass surgery at this institution are recommended to achieve a goal of 10% total body weight (TBW) loss prior to surgery. The objective of this study was to determine whether preoperative TBW correlated with 3- and 4-year weight loss outcome.

Methods

This study was conducted prospectively at a large teaching hospital. All adult patients with 3- and 4-year follow-up data since the start of the study in 1998 to September 2007 were included. All data are expressed as mean ± SD. Pairwise correlation and ordinary least squares regression analysis was used to determine the strength of association between preoperative TBW loss and weight loss at 3 and 4 years.

Results

One hundred fifty patients (120 females), age 45.3 ± 8.9 years, were included. Their body mass indexes (BMIs), preoperatively and after 3 years, were 52.2 ± 9.8 and 35.4 ± 8.2 kg/m2, respectively. There was a significant correlation between preoperative and 3-year TBW lost (9.5 ± 6.8% vs 31.9 ± 11.7%, r = 0.302, p = 0.0002) and between excess body weight (EBW) lost preoperatively and after 3 years (16.1 ± 11.3% vs 55.1 ± 20.2%, r = 0.225, p = 0.006). Ninety five patients had follow-up data available at 4 years. Their mean preoperative BMI was 52.6 ± 9.7 kg/m2 and decreased to 37.5 ± 9.0 kg/m2. The TBW loss prior to and after surgery (10.0 ± 6.5% vs 29.4 ± 11.5%) was significantly correlated (r = 0.247, p = 0.015). The EBW loss preoperatively and after 4 years correlated positively (17.1 ± 11.1% vs 50.8 ± 19.8%, r = 0.205, p = 0.046).

Conclusion

There is a significant correlation between weight loss attained preoperatively and sustained weight loss at 3 and 4 years.
Literatur
1.
Zurück zum Zitat Anderson JW, Conley SB, Nicholas AS. One hundred pound weight losses with an intensive behavioral program: changes in risk factors in 118 patients with long-term follow-up. Am J Clin Nutr. 2007;86(2):301–7.PubMed Anderson JW, Conley SB, Nicholas AS. One hundred pound weight losses with an intensive behavioral program: changes in risk factors in 118 patients with long-term follow-up. Am J Clin Nutr. 2007;86(2):301–7.PubMed
2.
Zurück zum Zitat Hill JO. Understanding and addressing the epidemic of obesity: an energy balance perspective. Endocr Rev. 2006;27(7):750–61.PubMed Hill JO. Understanding and addressing the epidemic of obesity: an energy balance perspective. Endocr Rev. 2006;27(7):750–61.PubMed
3.
Zurück zum Zitat Hill JO, Wyatt HR. Role of physical activity in preventing and treating obesity. J Appl Physiol. 2005;99(2):765–70.PubMedCrossRef Hill JO, Wyatt HR. Role of physical activity in preventing and treating obesity. J Appl Physiol. 2005;99(2):765–70.PubMedCrossRef
4.
Zurück zum Zitat Evans RK, Bond DS, Wolfe LG, et al. Participation in 150 min/week of moderate or higher intensity physical activity yields greater weight loss after gastric bypass surgery. Surg Obes Relat Dis. 2007;3(5):526–30.PubMedCrossRef Evans RK, Bond DS, Wolfe LG, et al. Participation in 150 min/week of moderate or higher intensity physical activity yields greater weight loss after gastric bypass surgery. Surg Obes Relat Dis. 2007;3(5):526–30.PubMedCrossRef
5.
Zurück zum Zitat Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med. 1995;332(10):621–8.PubMedCrossRef Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med. 1995;332(10):621–8.PubMedCrossRef
6.
Zurück zum Zitat Badman MK, Flier JS. The gut and energy balance: visceral allies in the obesity wars. Science. 2005;305(5717):1909–14.CrossRef Badman MK, Flier JS. The gut and energy balance: visceral allies in the obesity wars. Science. 2005;305(5717):1909–14.CrossRef
7.
Zurück zum Zitat Morinigo R, Moize V, Musri M, et al. Glucagon-like peptide 1, peptide YY, hunger and satiety after gastric bypass surgery in morbidly obese subjects. J Clin Endocrinol Metab. 2006;91(5):1735–40.PubMedCrossRef Morinigo R, Moize V, Musri M, et al. Glucagon-like peptide 1, peptide YY, hunger and satiety after gastric bypass surgery in morbidly obese subjects. J Clin Endocrinol Metab. 2006;91(5):1735–40.PubMedCrossRef
8.
Zurück zum Zitat Chan JL, Mon EC, Stoyneva V, et al. Peptide YY levels are elevated after gastric bypass surgery. Obesity. 2006;14(2):194–8.PubMedCrossRef Chan JL, Mon EC, Stoyneva V, et al. Peptide YY levels are elevated after gastric bypass surgery. Obesity. 2006;14(2):194–8.PubMedCrossRef
9.
Zurück zum Zitat Korner J, Bessler M, Cirilo LJ, et al. Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY and insulin. J Clin Endocrinol Metab. 2005;90(1):359–65.PubMedCrossRef Korner J, Bessler M, Cirilo LJ, et al. Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY and insulin. J Clin Endocrinol Metab. 2005;90(1):359–65.PubMedCrossRef
10.
Zurück zum Zitat Korner J, Inabnet W, Conwell IM, et al. Differential effects of gastric bypass and banding on circulating gut hormone and leptin levels. Obesity. 2006;14(9):1553–6PubMedCrossRef Korner J, Inabnet W, Conwell IM, et al. Differential effects of gastric bypass and banding on circulating gut hormone and leptin levels. Obesity. 2006;14(9):1553–6PubMedCrossRef
11.
Zurück zum Zitat Alvarado R, Alami RS, Hsu G, Safadi BY, Sanchez BR, Morton JM, et al. The impact of preoperative weight loss undergoing laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2005;15:1282–6.PubMedCrossRef Alvarado R, Alami RS, Hsu G, Safadi BY, Sanchez BR, Morton JM, et al. The impact of preoperative weight loss undergoing laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2005;15:1282–6.PubMedCrossRef
12.
Zurück zum Zitat Alami RS, Morton JM, Schuster R, Lie J, Sanchez BR, Peters A, et al. Is there a benefit to preoperative weight loss in gastric bypass patients? A prospective randomized trial. Surg Obes Relat Disord. 2007;3:141–6.CrossRef Alami RS, Morton JM, Schuster R, Lie J, Sanchez BR, Peters A, et al. Is there a benefit to preoperative weight loss in gastric bypass patients? A prospective randomized trial. Surg Obes Relat Disord. 2007;3:141–6.CrossRef
13.
Zurück zum Zitat Still CD, Benotti P, Wood GC, Gerhard GS, Petrick A, Reed M, et al. Outcomes of preoperative weight loss in high risk patients undergoing gastric bypass surgery. Arch Surg. 2007;142(10):994–8.PubMedCrossRef Still CD, Benotti P, Wood GC, Gerhard GS, Petrick A, Reed M, et al. Outcomes of preoperative weight loss in high risk patients undergoing gastric bypass surgery. Arch Surg. 2007;142(10):994–8.PubMedCrossRef
14.
Zurück zum Zitat Buchwald H. Bariatric surgery for morbid obesity: health implications for patients, health professionals, and third party payers. J Am Coll Surg. 2005;200:593–604.PubMedCrossRef Buchwald H. Bariatric surgery for morbid obesity: health implications for patients, health professionals, and third party payers. J Am Coll Surg. 2005;200:593–604.PubMedCrossRef
15.
Zurück zum Zitat Jakicic JM, Wing RR, Winters-Hart C. Relationship of physical activity to eating behaviors and weight loss in women. Med Sci Sports Exerc. 2002;34(10):1653–9.PubMedCrossRef Jakicic JM, Wing RR, Winters-Hart C. Relationship of physical activity to eating behaviors and weight loss in women. Med Sci Sports Exerc. 2002;34(10):1653–9.PubMedCrossRef
16.
Zurück zum Zitat Blumenthal JA, Babyak MA, Moore KA, et al. Effects of exercise training on older patients with major depression. Arch Intern Med. 1999;159(19):2349–56.PubMedCrossRef Blumenthal JA, Babyak MA, Moore KA, et al. Effects of exercise training on older patients with major depression. Arch Intern Med. 1999;159(19):2349–56.PubMedCrossRef
17.
Zurück zum Zitat Liu RC, Sabnis AA, Forsyth C, Chand B. The effects of acute preoperative weight loss on laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2005;15:1396–402.PubMedCrossRef Liu RC, Sabnis AA, Forsyth C, Chand B. The effects of acute preoperative weight loss on laparoscopic Roux-en-Y gastric bypass. Obes Surg. 2005;15:1396–402.PubMedCrossRef
18.
Zurück zum Zitat Buchwald H, Avidor Y, Braunwald E. Bariatric surgery: a systematic review and meta analysis. JAMA. 2004;292(14):1724–37.PubMedCrossRef Buchwald H, Avidor Y, Braunwald E. Bariatric surgery: a systematic review and meta analysis. JAMA. 2004;292(14):1724–37.PubMedCrossRef
Metadaten
Titel
Preoperative Weight Loss as a Predictor of Long-term Success Following Roux-en-Y Gastric Bypass
verfasst von
Sharon Alger-Mayer
John M. Polimeni
Margaret Malone
Publikationsdatum
01.07.2008
Verlag
Springer-Verlag
Erschienen in
Obesity Surgery / Ausgabe 7/2008
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-008-9482-2

Weitere Artikel der Ausgabe 7/2008

Obesity Surgery 7/2008 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.