Erschienen in:
01.05.2011 | Clinical Research
Laparoscopic Sleeve Gastrectomy with Duodenojejunal Bypass for the Treatment of Type 2 Diabetes in Non-obese Patients: Technique and Preliminary Results
verfasst von:
Salvador Antonio Navarrete, Jose Luis Leyba, Salvador Navarrete Llopis
Erschienen in:
Obesity Surgery
|
Ausgabe 5/2011
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Abstract
Background
Medical treatment of type 2 diabetes has often insufficient clinical results at long term. Although the surgical option is a well-established alternative for obese patients, the procedures in non-obese are currently being developed.
Methods
A 12-month prospective trial with ten diabetic non-obese patients who underwent laparoscopic sleeve gastrectomy with duodenojejunal bypass is presented. Changes in fasting blood glucose, HbA1c, weight, and BMI were determined.
Results
There was a significant reduction in fasting glycemia and HbA1c at 1 year postoperative (p < 0.004). One patient had an intra-abdominal bleeding and a wound infection treated with blood transfusion and antibiotic therapy, respectively. The BMI decreased 12.1% and in any case it was reduced to less than 20 kg/m2.
Conclusions
Laparoscopic sleeve gastrectomy with duodenojejunal bypass is a promising procedure for the treatment of non-obese patients with type 2 diabetes. Studies with large number of patients and longer follow-up are necessary to make definitive conclusions.