Erschienen in:
01.10.2012 | Clinical Research
Effect of Laparoscopic Roux-en-Y Gastroenterostomy with BMI < 35 kg/m2 in Type 2 Diabetes Mellitus
verfasst von:
Liyong Zhu, Zhaohui Mo, Xiangwu Yang, Shengping Liu, Guohui Wang, Pengzhou Li, Juan Tan, Fei Ye, Jeff Strain, Ibrahim Im, Shaihong Zhu
Erschienen in:
Obesity Surgery
|
Ausgabe 10/2012
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Abstract
Background
Roux-en-Y gastric bypass (RGB) has been endorsed by the “First World Congress on International Therapies for Type 2 diabetes” as a possible therapeutic option in patients with type 2 diabetes with a body mass index (BMI) of less than 35 kg/m2. In the present study, we assessed the improvement in clinical indicators associated with laparoscopic Roux-en-Y gastric bypass (LRYGB) in patients with non-obese type 2 diabetes mellitus (T2DM).
Methods
LRYGB was performed in 30 T2DM patients with a BMI <35 kg/m2. The patients were followed up for 1 year. Pre- and postoperative changes in BMI, waist circumference, and biochemical indicators including fasting plasma glucose and glycosylated hemoglobin were recorded.
Results
Significant reduction in glycosylated hemoglobin from 8.02 ± 1.77 to 5.59 ± 1.02 % (p < 0.05) at 12 months was noted. Diabetes was completely resolved in nine cases, resulting in discontinuation of diabetes-related medication. No significant surgical complications occurred.
Conclusions
LRYGB is beneficial for non-obese T2DM patients in China.