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Erschienen in: Obesity Surgery 10/2012

01.10.2012 | Clinical Research

Effect of Laparoscopic Roux-en-Y Gastroenterostomy with BMI < 35 kg/m2 in Type 2 Diabetes Mellitus

verfasst von: Liyong Zhu, Zhaohui Mo, Xiangwu Yang, Shengping Liu, Guohui Wang, Pengzhou Li, Juan Tan, Fei Ye, Jeff Strain, Ibrahim Im, Shaihong Zhu

Erschienen in: Obesity Surgery | Ausgabe 10/2012

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Abstract

Background

Roux-en-Y gastric bypass (RGB) has been endorsed by the “First World Congress on International Therapies for Type 2 diabetes” as a possible therapeutic option in patients with type 2 diabetes with a body mass index (BMI) of less than 35 kg/m2. In the present study, we assessed the improvement in clinical indicators associated with laparoscopic Roux-en-Y gastric bypass (LRYGB) in patients with non-obese type 2 diabetes mellitus (T2DM).

Methods

LRYGB was performed in 30 T2DM patients with a BMI <35 kg/m2. The patients were followed up for 1 year. Pre- and postoperative changes in BMI, waist circumference, and biochemical indicators including fasting plasma glucose and glycosylated hemoglobin were recorded.

Results

Significant reduction in glycosylated hemoglobin from 8.02 ± 1.77 to 5.59 ± 1.02 % (p < 0.05) at 12 months was noted. Diabetes was completely resolved in nine cases, resulting in discontinuation of diabetes-related medication. No significant surgical complications occurred.

Conclusions

LRYGB is beneficial for non-obese T2DM patients in China.
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Metadaten
Titel
Effect of Laparoscopic Roux-en-Y Gastroenterostomy with BMI < 35 kg/m2 in Type 2 Diabetes Mellitus
verfasst von
Liyong Zhu
Zhaohui Mo
Xiangwu Yang
Shengping Liu
Guohui Wang
Pengzhou Li
Juan Tan
Fei Ye
Jeff Strain
Ibrahim Im
Shaihong Zhu
Publikationsdatum
01.10.2012
Verlag
Springer-Verlag
Erschienen in
Obesity Surgery / Ausgabe 10/2012
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-012-0694-0

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