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Erschienen in: Obesity Surgery 1/2015

01.01.2015 | Review Article

The Long-Term Effects of Bariatric Surgery for Type 2 Diabetes: Systematic Review and Meta-analysis of Randomized and Non-randomized Evidence

verfasst von: Jiajie Yu, Xu Zhou, Ling Li, Sheyu Li, Jing Tan, Youping Li, Xin Sun

Erschienen in: Obesity Surgery | Ausgabe 1/2015

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Abstract

This study aims to assess the long-term effects of bariatric surgery on type 2 diabetic patients. We searched Cochrane Library, PubMed, and EMbase up to Dec 2013. Randomized controlled trials (RCTs) and cohort studies of bariatric surgery for diabetes patients that reported data with more than 2 years of follow-up were included. We used rigorous methods to screen studies for eligibility and collected data using standardized forms. Where applicable, we pooled data by meta-analyses. Twenty-six studies, including 2 RCTs and 24 cohort studies that enrolled 7883 patients, proved eligible. Despite the differences in the design, those studies consistently showed that bariatric surgery offered better treatment outcomes than non-surgical options. Pooling of cohort studies showed that BMI decreased by 13.4 kg/m2 (95 % confidence interval (CI), −17.7 to −9.1), fasting blood glucose by 59.7 mg/dl (95 % CI, −74.6 to −44.9), and glycated hemoglobin by 1.8 % (95 % CI, −2.4 to −1.3). Diabetes was improved or in remission in 89.2 % of patients, and 64.7 % of patients was in remission. Weight loss and diabetes remission were greatest in patients undergoing biliopancreatic diversion/duodenal switch, followed by gastric bypass, sleeve gastrectomy, and adjustable gastric banding. Bariatric surgery may achieve sustained weight loss, glucose control, and diabetes remission. Large randomized trials with long-term follow-up are warranted to demonstrate the effect on outcomes important to patients (e.g., cardiovascular events).
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Literatur
3.
Zurück zum Zitat Picot J, Jones J, Colquitt JL, et al. The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation. Health Technol Assess. 2009;13(41):1–190. 215-357 PMID:19726018.CrossRef Picot J, Jones J, Colquitt JL, et al. The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation. Health Technol Assess. 2009;13(41):1–190. 215-357 PMID:19726018.CrossRef
4.
Zurück zum Zitat Whitlock G, Lewington S, Sherliker P, et al. Body-mass index and cause-specific mortality in 900,000 adults: collaborative analysis of 57 prospective studies. Lancet. 2009;373(9669):1083–96. Epub 2009 Mar 18. PMID:19299006.PubMedCrossRef Whitlock G, Lewington S, Sherliker P, et al. Body-mass index and cause-specific mortality in 900,000 adults: collaborative analysis of 57 prospective studies. Lancet. 2009;373(9669):1083–96. Epub 2009 Mar 18. PMID:19299006.PubMedCrossRef
5.
Zurück zum Zitat Mazzone T, Chait A, Plutzky J. Cardiovascular disease risk in type 2 diabetes mellitus: insight from mechanistic studies. Lancet. 2008;371(9626):1800–9. PMID:18502305.PubMedCentralPubMedCrossRef Mazzone T, Chait A, Plutzky J. Cardiovascular disease risk in type 2 diabetes mellitus: insight from mechanistic studies. Lancet. 2008;371(9626):1800–9. PMID:18502305.PubMedCentralPubMedCrossRef
6.
Zurück zum Zitat Colberg SR, Sigal RJ, Fernhall B, et al. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement. Diabetes Care. 2010;33(12):2692–6. PMID:21115771.PubMedCentralPubMedCrossRef Colberg SR, Sigal RJ, Fernhall B, et al. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement. Diabetes Care. 2010;33(12):2692–6. PMID:21115771.PubMedCentralPubMedCrossRef
7.
Zurück zum Zitat Resnick HE, Foster GL, Beardsley J, Ratner RE. Achievement of American Diabetes Association clinical practice recommendations among U.S. adults with diabetes, 1999–2002: the National Health and Nutrition Examination Survey. Diabetes Care. 2006;29(3):531–7.PubMedCrossRef Resnick HE, Foster GL, Beardsley J, Ratner RE. Achievement of American Diabetes Association clinical practice recommendations among U.S. adults with diabetes, 1999–2002: the National Health and Nutrition Examination Survey. Diabetes Care. 2006;29(3):531–7.PubMedCrossRef
8.
Zurück zum Zitat Bennett WL, Maruthur NM, Singh S, et al. Comparative effectiveness and safety of medications for type 2 diabetes: an update including new drugs and 2-drug combinations. Ann Intern Med. 2011;154(9):602–13. Epub 2011 Mar 14. PMID:21403054.PubMedCentralPubMedCrossRef Bennett WL, Maruthur NM, Singh S, et al. Comparative effectiveness and safety of medications for type 2 diabetes: an update including new drugs and 2-drug combinations. Ann Intern Med. 2011;154(9):602–13. Epub 2011 Mar 14. PMID:21403054.PubMedCentralPubMedCrossRef
9.
Zurück zum Zitat Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care. 2004;27(5):1218–24. PMID:1511553.PubMedCrossRef Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care. 2004;27(5):1218–24. PMID:1511553.PubMedCrossRef
10.
Zurück zum Zitat Gloy VL, Briel M, Bhatt DL, et al. Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials. BMJ. 2013;347:f5934. PMID:24149519.PubMedCentralPubMedCrossRef Gloy VL, Briel M, Bhatt DL, et al. Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials. BMJ. 2013;347:f5934. PMID:24149519.PubMedCentralPubMedCrossRef
11.
Zurück zum Zitat Ribaric G, Buchwald JN, McGlennon TW. Diabetes and weight in comparative studies of bariatric surgery vs conventional medical therapy: a systematic review and meta-analysis. Obes Surg. 2014;24(3):437–55. PMID:24374842.PubMedCentralPubMedCrossRef Ribaric G, Buchwald JN, McGlennon TW. Diabetes and weight in comparative studies of bariatric surgery vs conventional medical therapy: a systematic review and meta-analysis. Obes Surg. 2014;24(3):437–55. PMID:24374842.PubMedCentralPubMedCrossRef
12.
Zurück zum Zitat American Diabetes Association. Standards of medical care in diabetes--2013. Diabetes Care. 2013;36 Suppl 1:S11–66. PMID:23264422.PubMedCentralCrossRef American Diabetes Association. Standards of medical care in diabetes--2013. Diabetes Care. 2013;36 Suppl 1:S11–66. PMID:23264422.PubMedCentralCrossRef
13.
Zurück zum Zitat Dixon JB, Zimmet P, Alberti KG, et al. Bariatric surgery: an IDF statement for obese type 2 diabetes. Diabet Med. 2011;28(6):628–42. PMID: 21480973.PubMedCentralPubMedCrossRef Dixon JB, Zimmet P, Alberti KG, et al. Bariatric surgery: an IDF statement for obese type 2 diabetes. Diabet Med. 2011;28(6):628–42. PMID: 21480973.PubMedCentralPubMedCrossRef
14.
Zurück zum Zitat Buchwald H, Estok R, Fahrbach K, et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med. 2009;122(3):248–256.e5. PMID:19272486.PubMedCrossRef Buchwald H, Estok R, Fahrbach K, et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med. 2009;122(3):248–256.e5. PMID:19272486.PubMedCrossRef
15.
Zurück zum Zitat Maggard-Gibbons M, Maglione M, Livhits M, et al. Bariatric surgery for weight loss and glycemic control in nonmorbidly obese adults with diabetes: a systematic review. JAMA. 2013;309(21):2250–61. PMID:23736734.PubMedCrossRef Maggard-Gibbons M, Maglione M, Livhits M, et al. Bariatric surgery for weight loss and glycemic control in nonmorbidly obese adults with diabetes: a systematic review. JAMA. 2013;309(21):2250–61. PMID:23736734.PubMedCrossRef
16.
Zurück zum Zitat Li Q, Chen L, Yang Z, et al. Metabolic effects of bariatric surgery in type 2 diabetic patients with body mass index <35 kg/m2. Diabetes Obes Metab. 2012;14(3):262–70. Epub 2011 Dec 27. PMID:22051116.PubMedCrossRef Li Q, Chen L, Yang Z, et al. Metabolic effects of bariatric surgery in type 2 diabetic patients with body mass index <35 kg/m2. Diabetes Obes Metab. 2012;14(3):262–70. Epub 2011 Dec 27. PMID:22051116.PubMedCrossRef
18.
Zurück zum Zitat Higgins JPT, Green S, eds. Cochrane handbook for systematic reviews of interventions version 5.1.0. The Cochrane Collaboration, 2011 [updated 2011 March, cited 2013 Dec]. available from http://www.cochrane-handbook.org. Higgins JPT, Green S, eds. Cochrane handbook for systematic reviews of interventions version 5.1.0. The Cochrane Collaboration, 2011 [updated 2011 March, cited 2013 Dec]. available from http://​www.​cochrane-handbook.​org.
19.
Zurück zum Zitat Schauer PR, Bhatt DL, Kirwan JP, et al. Bariatric surgery versus intensive medical therapy for diabetes—3-year outcomes. N Engl J Med. 2014;370(21):2002–13. Epub 2014 Mar 31. PMID: 24679060.PubMedCrossRef Schauer PR, Bhatt DL, Kirwan JP, et al. Bariatric surgery versus intensive medical therapy for diabetes—3-year outcomes. N Engl J Med. 2014;370(21):2002–13. Epub 2014 Mar 31. PMID: 24679060.PubMedCrossRef
20.
Zurück zum Zitat Lee WJ, Chong K, Lin YH, Wei JH, Chen SC. Laparoscopic sleeve gastrectomy versus single anastomosis (mini) gastric bypass for the treatment of type 2 diabetes mellitus 5-year results of a randomized trial and study of incretin effect. Obes Surg. 2014 Jun 26. Epub ahead of print. PMID: 24965545. Lee WJ, Chong K, Lin YH, Wei JH, Chen SC. Laparoscopic sleeve gastrectomy versus single anastomosis (mini) gastric bypass for the treatment of type 2 diabetes mellitus 5-year results of a randomized trial and study of incretin effect. Obes Surg. 2014 Jun 26. Epub ahead of print. PMID: 24965545.
21.
Zurück zum Zitat Abbatini F, Rizzello M, Casella G, et al. Long-term effects of laparoscopic sleeve gastrectomy, gastric bypass, and adjustable gastric banding on type 2 diabetes. Surg Endosc. 2010;24(5):1005–10. Epub 2009 Oct 29. PMID:19866235.PubMedCrossRef Abbatini F, Rizzello M, Casella G, et al. Long-term effects of laparoscopic sleeve gastrectomy, gastric bypass, and adjustable gastric banding on type 2 diabetes. Surg Endosc. 2010;24(5):1005–10. Epub 2009 Oct 29. PMID:19866235.PubMedCrossRef
22.
Zurück zum Zitat Alexandrides TK, Skroubis G, Kalfarentzos F. Resolution of diabetes mellitus and metabolic syndrome following Roux-en-Y gastric bypass and a variant of biliopancreatic diversion in patients with morbid obesity. Obes Surg. 2007;17(2):176–84. PMID:17476868.PubMedCrossRef Alexandrides TK, Skroubis G, Kalfarentzos F. Resolution of diabetes mellitus and metabolic syndrome following Roux-en-Y gastric bypass and a variant of biliopancreatic diversion in patients with morbid obesity. Obes Surg. 2007;17(2):176–84. PMID:17476868.PubMedCrossRef
23.
Zurück zum Zitat Brethauer SA, Aminian A, Romero-Talamás H, et al. Can diabetes be surgically cured? Long-term metabolic effects of bariatric surgery in obese patients with type 2 diabetes mellitus. Ann Surg. 2013;258(4):628–36. PMID:24018646.PubMedCentralPubMed Brethauer SA, Aminian A, Romero-Talamás H, et al. Can diabetes be surgically cured? Long-term metabolic effects of bariatric surgery in obese patients with type 2 diabetes mellitus. Ann Surg. 2013;258(4):628–36. PMID:24018646.PubMedCentralPubMed
24.
Zurück zum Zitat Iaconelli A, Panunzi S, De Gaetano A, et al. Effects of bilio-pancreatic diversion on diabetic complications: a 10-year follow-up. Diabetes Care. 2011;34(3):561–7. Epub 2011 Jan 31. PMID:21282343.PubMedCentralPubMedCrossRef Iaconelli A, Panunzi S, De Gaetano A, et al. Effects of bilio-pancreatic diversion on diabetic complications: a 10-year follow-up. Diabetes Care. 2011;34(3):561–7. Epub 2011 Jan 31. PMID:21282343.PubMedCentralPubMedCrossRef
25.
Zurück zum Zitat Jimenez A, Casamitjana R, Flores L, et al. Long-term effects of sleeve gastrectomy and Roux-en-Y gastric bypass surgery on type 2 diabetes mellitus in morbidly obese subjects. Ann Surg. 2012;256(6):1023–9. PMID:22968072.PubMedCrossRef Jimenez A, Casamitjana R, Flores L, et al. Long-term effects of sleeve gastrectomy and Roux-en-Y gastric bypass surgery on type 2 diabetes mellitus in morbidly obese subjects. Ann Surg. 2012;256(6):1023–9. PMID:22968072.PubMedCrossRef
26.
Zurück zum Zitat MacDonald KG, Long SD, Swanson MS, et al. The gastric bypass operation reduces the progression and mortality of non-insulin-dependent diabetes mellitus. J Gastrointest Surg. 1997;1(3):213–20. PMID:9834350.PubMedCrossRef MacDonald KG, Long SD, Swanson MS, et al. The gastric bypass operation reduces the progression and mortality of non-insulin-dependent diabetes mellitus. J Gastrointest Surg. 1997;1(3):213–20. PMID:9834350.PubMedCrossRef
27.
Zurück zum Zitat Sjöström L, Peltonen M, Jacobson P, et al. Association of bariatric surgery with long-term remission of type 2 diabetes and with microvascular and macrovascular complications. JAMA. 2014;311(22):2297–304. PMID:24915261.PubMedCrossRef Sjöström L, Peltonen M, Jacobson P, et al. Association of bariatric surgery with long-term remission of type 2 diabetes and with microvascular and macrovascular complications. JAMA. 2014;311(22):2297–304. PMID:24915261.PubMedCrossRef
28.
Zurück zum Zitat Abbatini F, Capoccia D, Casella G, Soricelli E, Leonetti F, Basso N. Long-term remission of type 2 diabetes in morbidly obese patients after sleeve gastrectomy. Surg Obes Relat Dis. 2013;9(4):498–502. Epub 2012 Sep 18. PMID:23290187.PubMedCrossRef Abbatini F, Capoccia D, Casella G, Soricelli E, Leonetti F, Basso N. Long-term remission of type 2 diabetes in morbidly obese patients after sleeve gastrectomy. Surg Obes Relat Dis. 2013;9(4):498–502. Epub 2012 Sep 18. PMID:23290187.PubMedCrossRef
29.
Zurück zum Zitat Arterburn DE, Bogart A, Sherwood NE, et al. A multisite study of long-term remission and relapse of type 2 diabetes mellitus following gastric bypass. Obes Surg. 2013;23(1):93–102. PMID: 23161525.PubMedCrossRef Arterburn DE, Bogart A, Sherwood NE, et al. A multisite study of long-term remission and relapse of type 2 diabetes mellitus following gastric bypass. Obes Surg. 2013;23(1):93–102. PMID: 23161525.PubMedCrossRef
30.
Zurück zum Zitat Caiazzo R, Arnalsteen L, Pigeyre M, et al. Long-term metabolic outcome and quality of life after laparoscopic adjustable gastric banding in obese patients with type 2 diabetes mellitus or impaired fasting glucose. Br J Surg. 2010;97(6):884–91. PMID:20473998.PubMedCrossRef Caiazzo R, Arnalsteen L, Pigeyre M, et al. Long-term metabolic outcome and quality of life after laparoscopic adjustable gastric banding in obese patients with type 2 diabetes mellitus or impaired fasting glucose. Br J Surg. 2010;97(6):884–91. PMID:20473998.PubMedCrossRef
31.
Zurück zum Zitat Chikunguwo SM, Wolfe LG, Dodson P, et al. Analysis of factors associated with durable remission of diabetes after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2010;6(3):254–9. Epub 2009 Nov 10. PMID:20303324.PubMedCrossRef Chikunguwo SM, Wolfe LG, Dodson P, et al. Analysis of factors associated with durable remission of diabetes after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2010;6(3):254–9. Epub 2009 Nov 10. PMID:20303324.PubMedCrossRef
32.
Zurück zum Zitat Cohen RV, Pinheiro JC, Schiavon CA, Salles JE, Wajchenberg BL, Cummings DE. Effects of gastric bypass surgery in patients with type 2 diabetes and only mild obesity. Diabetes Care. 2012;35(7):1420–8. PMID:22723580.PubMedCentralPubMedCrossRef Cohen RV, Pinheiro JC, Schiavon CA, Salles JE, Wajchenberg BL, Cummings DE. Effects of gastric bypass surgery in patients with type 2 diabetes and only mild obesity. Diabetes Care. 2012;35(7):1420–8. PMID:22723580.PubMedCentralPubMedCrossRef
33.
Zurück zum Zitat Cruz-Munoz N, Messiah SE, Arheart KL, Lopez-Mitnik G, Lipshultz SE, Livingstone A. Bariatric surgery significantly decreases the prevalence of type 2 diabetes mellitus and pre-diabetes among morbidly obese multiethnic adults: long-term results. J Am Coll Surg. 2011;212(4):505–11. PMID:21463779.PubMedCrossRef Cruz-Munoz N, Messiah SE, Arheart KL, Lopez-Mitnik G, Lipshultz SE, Livingstone A. Bariatric surgery significantly decreases the prevalence of type 2 diabetes mellitus and pre-diabetes among morbidly obese multiethnic adults: long-term results. J Am Coll Surg. 2011;212(4):505–11. PMID:21463779.PubMedCrossRef
34.
Zurück zum Zitat DePaula AL, Stival AR, DePaula CC, Halpern A, Vencio S. Surgical treatment of type 2 diabetes in patients with BMI below 35: mid-term outcomes of the laparoscopic ileal interposition associated with a sleeve gastrectomy in 202 consecutive cases. J Gastrointest Surg. 2012;16(5):967–76. Epub 2012 Feb 18. PMID:22350720.PubMedCrossRef DePaula AL, Stival AR, DePaula CC, Halpern A, Vencio S. Surgical treatment of type 2 diabetes in patients with BMI below 35: mid-term outcomes of the laparoscopic ileal interposition associated with a sleeve gastrectomy in 202 consecutive cases. J Gastrointest Surg. 2012;16(5):967–76. Epub 2012 Feb 18. PMID:22350720.PubMedCrossRef
35.
Zurück zum Zitat DiGiorgi M, Rosen DJ, Choi JJ, et al. Re-emergence of diabetes after gastric bypass in patients with mid- to long-term follow-up. Surg Obes Relat Dis. 2010;6(3):249–53. Epub 2009 Oct 29. PMID:20510288.PubMedCrossRef DiGiorgi M, Rosen DJ, Choi JJ, et al. Re-emergence of diabetes after gastric bypass in patients with mid- to long-term follow-up. Surg Obes Relat Dis. 2010;6(3):249–53. Epub 2009 Oct 29. PMID:20510288.PubMedCrossRef
36.
Zurück zum Zitat Heneghan HM, Cetin D, Navaneethan SD, Orzech N, Brethauer SA, Schauer PR. Effects of bariatric surgery on diabetic nephropathy after 5 years of follow-up. Surg Obes Relat Dis. 2013;9(1):7–14. Epub 2012 Oct 12. PMID:23211651.PubMedCrossRef Heneghan HM, Cetin D, Navaneethan SD, Orzech N, Brethauer SA, Schauer PR. Effects of bariatric surgery on diabetic nephropathy after 5 years of follow-up. Surg Obes Relat Dis. 2013;9(1):7–14. Epub 2012 Oct 12. PMID:23211651.PubMedCrossRef
37.
Zurück zum Zitat Kim S, Richards WO. Long-term follow-up of the metabolic profiles in obese patients with type 2 diabetes mellitus after Roux-en-Y gastric bypass. Ann Surg. 2010;251(6):1049–55. PMID:20485144.PubMedCrossRef Kim S, Richards WO. Long-term follow-up of the metabolic profiles in obese patients with type 2 diabetes mellitus after Roux-en-Y gastric bypass. Ann Surg. 2010;251(6):1049–55. PMID:20485144.PubMedCrossRef
38.
Zurück zum Zitat Kota SK, Ugale S, Gupta N, et al. Ileal interposition with sleeve gastrectomy for treatment of type 2 diabetes mellitus. Indian J Endocrinol Meta. 2012;16(4):589–98. PMID:22837922.CrossRef Kota SK, Ugale S, Gupta N, et al. Ileal interposition with sleeve gastrectomy for treatment of type 2 diabetes mellitus. Indian J Endocrinol Meta. 2012;16(4):589–98. PMID:22837922.CrossRef
39.
Zurück zum Zitat Lakdawala M, Shaikh S, Bandukwala S, Remedios C, Shah M, Bhasker AG. Roux-en-Y gastric bypass stands the test of time: 5-year results in low body mass index (30–35 kg/m2) Indian patients with type 2 diabetes mellitus. Surg Obes Relat Dis. 2013;9(3):370–8. Epub 2012 Aug 7. PMID:23068107.PubMedCrossRef Lakdawala M, Shaikh S, Bandukwala S, Remedios C, Shah M, Bhasker AG. Roux-en-Y gastric bypass stands the test of time: 5-year results in low body mass index (30–35 kg/m2) Indian patients with type 2 diabetes mellitus. Surg Obes Relat Dis. 2013;9(3):370–8. Epub 2012 Aug 7. PMID:23068107.PubMedCrossRef
40.
Zurück zum Zitat Marinari GM, Papadia FS, Briatore L, Adami G, Scopinaro N. Type 2 diabetes and weight loss following biliopancreatic diversion for obesity. Obes Surg. 2006;16(11):1440–4. PMID:17132408.PubMedCrossRef Marinari GM, Papadia FS, Briatore L, Adami G, Scopinaro N. Type 2 diabetes and weight loss following biliopancreatic diversion for obesity. Obes Surg. 2006;16(11):1440–4. PMID:17132408.PubMedCrossRef
41.
Zurück zum Zitat Nora M, Guimaraes M, Almeida R, et al. Metabolic laparoscopic gastric bypass for obese patients with type 2 diabetes. Obes Surg. 2011;21(11):1643–9. PMID:21512818.PubMedCrossRef Nora M, Guimaraes M, Almeida R, et al. Metabolic laparoscopic gastric bypass for obese patients with type 2 diabetes. Obes Surg. 2011;21(11):1643–9. PMID:21512818.PubMedCrossRef
42.
Zurück zum Zitat Sultan S, Gupta D, Parikh M, et al. Five-year outcomes of patients with type 2 diabetes who underwent laparoscopic adjustable gastric banding. Surg Obes Relat Dis. 2010;6(4):373–6. Epub 2010 Mar 1. PMID:20627708.PubMedCrossRef Sultan S, Gupta D, Parikh M, et al. Five-year outcomes of patients with type 2 diabetes who underwent laparoscopic adjustable gastric banding. Surg Obes Relat Dis. 2010;6(4):373–6. Epub 2010 Mar 1. PMID:20627708.PubMedCrossRef
43.
Zurück zum Zitat Todkar JS, Shah SS, Shah PS, Gangwani J. Long-term effects of laparoscopic sleeve gastrectomy in morbidly obese subjects with type 2 diabetes mellitus. Surg Obes Relat Dis. 2010;6(2):142–5. Epub 2009 Jul 10. PMID:19733513.PubMedCrossRef Todkar JS, Shah SS, Shah PS, Gangwani J. Long-term effects of laparoscopic sleeve gastrectomy in morbidly obese subjects with type 2 diabetes mellitus. Surg Obes Relat Dis. 2010;6(2):142–5. Epub 2009 Jul 10. PMID:19733513.PubMedCrossRef
44.
Zurück zum Zitat Yang JT, Li CX, Liu HM, Gu HG, Chen P, Liu BH. Effects of subtotal gastrectomy and Roux-en-Y gastrojejunostomy on the clinical outcome of type 2 diabetes mellitus. J Surg Res. 2010;164(1):e67–71. Epub 2010 Jul 30. PMID:20863527.PubMedCrossRef Yang JT, Li CX, Liu HM, Gu HG, Chen P, Liu BH. Effects of subtotal gastrectomy and Roux-en-Y gastrojejunostomy on the clinical outcome of type 2 diabetes mellitus. J Surg Res. 2010;164(1):e67–71. Epub 2010 Jul 30. PMID:20863527.PubMedCrossRef
45.
Zurück zum Zitat Johnson BL, Blackhurst DW, Latham BB, et al. Bariatric surgery is associated with a reduction in major macrovascular and microvascular complications in moderately to severely obese patients with type 2 diabetes mellitus. J Am Coll Surg. 2013;216(4):545–56. Epub 2013 Feb 5. PMID:23391591.PubMedCrossRef Johnson BL, Blackhurst DW, Latham BB, et al. Bariatric surgery is associated with a reduction in major macrovascular and microvascular complications in moderately to severely obese patients with type 2 diabetes mellitus. J Am Coll Surg. 2013;216(4):545–56. Epub 2013 Feb 5. PMID:23391591.PubMedCrossRef
46.
Zurück zum Zitat Romeo S, Maglio C, Burza MA, et al. Cardiovascular events after bariatric surgery in obese subjects with type 2 diabetes. Diabetes Care. 2012;35(12):2613–7. PMID:22855732.PubMedCentralPubMedCrossRef Romeo S, Maglio C, Burza MA, et al. Cardiovascular events after bariatric surgery in obese subjects with type 2 diabetes. Diabetes Care. 2012;35(12):2613–7. PMID:22855732.PubMedCentralPubMedCrossRef
47.
Zurück zum Zitat Pontiroli AE, Morabito A. Long-term prevention of mortality in morbid obesity through bariatric surgery. A systematic review and meta-analysis of trials performed with gastric banding and gastric bypass. Ann Surg. 2011;253(3):484–7. PMID:21245741.PubMedCrossRef Pontiroli AE, Morabito A. Long-term prevention of mortality in morbid obesity through bariatric surgery. A systematic review and meta-analysis of trials performed with gastric banding and gastric bypass. Ann Surg. 2011;253(3):484–7. PMID:21245741.PubMedCrossRef
48.
Zurück zum Zitat Dimick JB, Welch HG, Birkmeyer JD. Surgical mortality as an indicator of hospital quality: the problem with small sample size. JAMA. 2004;292(7):847–51. PMID:15315999.PubMedCrossRef Dimick JB, Welch HG, Birkmeyer JD. Surgical mortality as an indicator of hospital quality: the problem with small sample size. JAMA. 2004;292(7):847–51. PMID:15315999.PubMedCrossRef
49.
Zurück zum Zitat Sjöström L. Review of the key results from the Swedish Obese Subjects (SOS) trial—a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273(3):219–34. Epub 2013 Feb 8. PMID:23163728.PubMedCrossRef Sjöström L. Review of the key results from the Swedish Obese Subjects (SOS) trial—a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273(3):219–34. Epub 2013 Feb 8. PMID:23163728.PubMedCrossRef
Metadaten
Titel
The Long-Term Effects of Bariatric Surgery for Type 2 Diabetes: Systematic Review and Meta-analysis of Randomized and Non-randomized Evidence
verfasst von
Jiajie Yu
Xu Zhou
Ling Li
Sheyu Li
Jing Tan
Youping Li
Xin Sun
Publikationsdatum
01.01.2015
Verlag
Springer US
Erschienen in
Obesity Surgery / Ausgabe 1/2015
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-014-1460-2

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S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

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Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.