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Erschienen in: Obesity Surgery 5/2018

06.03.2018 | Review Article

Does Bariatric Surgery Affect the Incidence of Endometrial Cancer Development? A Systematic Review

verfasst von: Alec A Winder, Malsha Kularatna, Andrew D. MacCormick

Erschienen in: Obesity Surgery | Ausgabe 5/2018

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Abstract

Obesity has been linked to an increased prevalence in multiple cancers. Studies have suggested a reduction in the overall risk of cancer after bariatric surgery. We reviewed the evidence for bariatric surgery reducing the risk of endometrial cancer. Data was extracted from PubMed, EMBASE, and Medline to perform a systematic review. Thirty-one full text articles were identified from 265 abstracts. Nine observational studies were relevant to endometrial cancer. In the five controlled studies, 462 of 113,032 (0.4%) patients receiving bariatric surgery versus 11,997 of 848,864 (1.4%) controls developed endometrial cancer, odds ratio of 0.317 (95% CI 0.161 to 0.627) using random effects model (P < 0.001). Bariatric surgery seems to reduce the risk of endometrial cancer; however, more research is required.
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Metadaten
Titel
Does Bariatric Surgery Affect the Incidence of Endometrial Cancer Development? A Systematic Review
verfasst von
Alec A Winder
Malsha Kularatna
Andrew D. MacCormick
Publikationsdatum
06.03.2018
Verlag
Springer US
Erschienen in
Obesity Surgery / Ausgabe 5/2018
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-018-3151-x

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