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Factors Associated with Weight Loss After Metabolic Surgery in a Multiethnic Sample of 1012 Patients

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Abstract

Background

Metabolic surgery is the most effective method for weight loss in the long-term treatment of morbid obesity and its comorbidities. The primary aim of this study was to examine factors associated with percent total weight loss (%TWL) after metabolic surgery among an ethnically diverse sample of patients.

Methods

A retrospective review was performed on 1012 patients who underwent either a sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) at our institution between January 2008 and June 2015.

Results

African Americans had a lower %TWL than non-Hispanic/Latino Whites at 6, 9, 12, 18, and 48 months. At all timeframes, there was a negative association between pre-surgery TWL and %TWL after surgery. Female sex was negatively associated with %TWL at 3 months only. Higher initial BMI was also associated with greater post-operative %TWL at 18, 24 and 36 months. Older patients had lower %TWL at 6, 9, 12 and 24 months post-surgery. Patients who received RYGB had greater %TWL than those who received SG at 3, 6, 9, 12, 24 and 36 months.

Conclusions

African Americans had a lower %TWL than non-Hispanic/Latino Whites at most time points; there were no other significant race/ethnicity or sex differences. BMI (greater initial BMI), age (lower) and RYGB were associated with a greater post-operative %TWL at certain post-surgery follow-up time points. A limitation of this study is that there was missing data at a number of time points due to lack of attendance at certain follow-up visits.

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Acknowledgements

Preliminary data of the paper was previously presented as an E-Poster entitled “Preoperative Weight Loss (POWL) as a Predictor of Percent Excess Weight Loss (%EWL) after Bariatric Surgery” at the 2018 American College of Surgeons Congress in Boston, MA.

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Correspondence to Roberto Bustos.

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The authors declare that they have no conflict of interest.

Ethics Statement

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. For this type of study, waiver of informed consent and waiver of authorization were granted by the IRB.

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Masrur, M., Bustos, R., Sanchez-Johnsen, L. et al. Factors Associated with Weight Loss After Metabolic Surgery in a Multiethnic Sample of 1012 Patients. OBES SURG 30, 975–981 (2020). https://doi.org/10.1007/s11695-019-04338-w

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