Skip to main content
Erschienen in: Journal of Robotic Surgery 3/2015

01.09.2015 | Original Article

Robotic versus laparoscopic surgery for mid or low rectal cancer in male patients after neoadjuvant chemoradiation therapy: comparison of short-term outcomes

verfasst von: Kursat Rahmi Serin, Fatma Ayca Gultekin, Burçin Batman, Serden Ay, Yersu Kapran, Sezer Saglam, Oktar Asoglu

Erschienen in: Journal of Robotic Surgery | Ausgabe 3/2015

Einloggen, um Zugang zu erhalten

Abstract

The aim of our study was to compare short-term outcomes of robotic and laparoscopic sphincter-saving total mesorectal excision (TME) in male patients with mid-low rectal cancer (RC) after neadjuvant chemoradiotherapy (NCRT). The study was conducted as a retrospective review of a prospectively maintained database, and we analyzed 14 robotic and 65 laparoscopic sphincter saving TME (R-TME and L-TME, respectively) performed by one surgeon between 2005 and 2013. Patient characteristics, perioperative recovery, postoperative complications and and pathology results were compared between the two groups. The patient characteristics did not differ significantly between the two groups. Median operating time was longer in the R-TME than in the L-TME group (182 min versus 140 min). Only two conversions occurred in the L-TME group. No difference was found between groups regarding perioperative recovery and postoperative complication rates. The median number of harvested lymph nodes was higher in the RTME than in the L-TME group (32 versus 23, p = 0.008). The median circumferential margin (CRM) was 10 mm in the R-TME group, 6.5 mm in the L-TME group (p = 0.047. The median distal resection margin (DRM) was 27.5 mm in the R-TME, 15 mm in the L-TME group (p = 0.014). Macroscopic grading of the specimen in the R-TME group was complete in all patients. In the L-TME group, grading was complete in 52 (80 %) and incomplete in 13 (20 %) cases (p = 0.109). R-TME is a safe and feasible procedure that facilitates performing of TME in male patients with mid-low RC after NCRT.
Literatur
1.
Zurück zum Zitat Daniels IR, Fisher SE, Heald RJ, Moran BJ (2007) Accurate staging, selective preoperative therapy, and optimal surgery improves outcome in rectal cancer: a review of the recent evidence. Colorectal Dis 9:290–301CrossRefPubMed Daniels IR, Fisher SE, Heald RJ, Moran BJ (2007) Accurate staging, selective preoperative therapy, and optimal surgery improves outcome in rectal cancer: a review of the recent evidence. Colorectal Dis 9:290–301CrossRefPubMed
2.
Zurück zum Zitat Kapiteijn E, Putter H, van de Velde CJ, Cooperative investigators of the Dutch ColoRectal Cancer Group (2002) Impact of the introduction and training of total mesorectal excision on recurrence and survival in rectal cancer in The Netherlands. Br J Surg 89:1142–1149CrossRefPubMed Kapiteijn E, Putter H, van de Velde CJ, Cooperative investigators of the Dutch ColoRectal Cancer Group (2002) Impact of the introduction and training of total mesorectal excision on recurrence and survival in rectal cancer in The Netherlands. Br J Surg 89:1142–1149CrossRefPubMed
3.
Zurück zum Zitat Martling A, Holm T, Rutqvist LE et al (2005) Impact of a surgical training program on rectal cancer outcomes in Stockholm. Br J Surg 92:225–229CrossRefPubMed Martling A, Holm T, Rutqvist LE et al (2005) Impact of a surgical training program on rectal cancer outcomes in Stockholm. Br J Surg 92:225–229CrossRefPubMed
4.
Zurück zum Zitat Wibe A, Møller B, Norstein J et al (2002) Norwegian Rectal Cancer Group. A national strategic change in treatment policy for rectal cancer–implementation of total mesorectal excision as routine treatment in Norway. A national audit. Dis Colon Rectum 45:857–866CrossRefPubMed Wibe A, Møller B, Norstein J et al (2002) Norwegian Rectal Cancer Group. A national strategic change in treatment policy for rectal cancer–implementation of total mesorectal excision as routine treatment in Norway. A national audit. Dis Colon Rectum 45:857–866CrossRefPubMed
5.
Zurück zum Zitat Minsky BD, Cohen AM, Kemeny N et al (1993) The efficacy of preoperative 5-fluorouracil, high-dose leucovorin, and sequential radiation therapy for unresectable rectal cancer. Cancer 71:3486–3492CrossRefPubMed Minsky BD, Cohen AM, Kemeny N et al (1993) The efficacy of preoperative 5-fluorouracil, high-dose leucovorin, and sequential radiation therapy for unresectable rectal cancer. Cancer 71:3486–3492CrossRefPubMed
6.
Zurück zum Zitat Theodoropoulos G, Wise WE, Padmanabhan A et al (2002) T-level downstaging and complete pathologic response after preoperative chemoradiation for advanced rectal cancer result in decreased recurrence and improved disease-free survival. Dis Colon Rectum 45:895–903CrossRefPubMed Theodoropoulos G, Wise WE, Padmanabhan A et al (2002) T-level downstaging and complete pathologic response after preoperative chemoradiation for advanced rectal cancer result in decreased recurrence and improved disease-free survival. Dis Colon Rectum 45:895–903CrossRefPubMed
8.
Zurück zum Zitat Poon JT, Law WL (2009) Laparoscopic resection for rectal cancer: a review. Ann Surg Oncol 16:3038–3047CrossRefPubMed Poon JT, Law WL (2009) Laparoscopic resection for rectal cancer: a review. Ann Surg Oncol 16:3038–3047CrossRefPubMed
9.
Zurück zum Zitat Guillou PJ, Quirke P, Thorpe P et al (2005) Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomized controlled trial. Lancet 365:1718–1726CrossRefPubMed Guillou PJ, Quirke P, Thorpe P et al (2005) Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomized controlled trial. Lancet 365:1718–1726CrossRefPubMed
10.
Zurück zum Zitat Baik SH, Kwon HY, Kim JS et al (2009) Robotic versus laparoscopic low anterior resection of rectal cancer: short-term outcome of a prospective comparative study. Ann Surg Oncol 16:1480–1487CrossRefPubMed Baik SH, Kwon HY, Kim JS et al (2009) Robotic versus laparoscopic low anterior resection of rectal cancer: short-term outcome of a prospective comparative study. Ann Surg Oncol 16:1480–1487CrossRefPubMed
11.
Zurück zum Zitat Bianchi PP, Ceriani C, Locatelli A et al (2010) Robotic versus laparoscopic total mesorectal excision for rectal cancer: a comparative analysis of oncological safety and short-term outcomes. Surg Endosc 24:2888–2894CrossRefPubMed Bianchi PP, Ceriani C, Locatelli A et al (2010) Robotic versus laparoscopic total mesorectal excision for rectal cancer: a comparative analysis of oncological safety and short-term outcomes. Surg Endosc 24:2888–2894CrossRefPubMed
12.
Zurück zum Zitat Park JS, Choi GS, Lim KH, Jang YS, Jun SH (2010) Robotic-assisted versus laparoscopic surgery for low rectal cancer: case-matched analysis of short-term outcomes. Ann Surg Oncol 17:3195–3202CrossRefPubMed Park JS, Choi GS, Lim KH, Jang YS, Jun SH (2010) Robotic-assisted versus laparoscopic surgery for low rectal cancer: case-matched analysis of short-term outcomes. Ann Surg Oncol 17:3195–3202CrossRefPubMed
13.
Zurück zum Zitat Saklani AP, Lim DR, Hur H et al (2013) Robotic versus laparoscopic surgery for mid-low rectal cancer after neoadjuvant chemoradiation therapy: comparison of oncologic outcomes. Int J Colorectal Dis 28:1689–1698CrossRefPubMed Saklani AP, Lim DR, Hur H et al (2013) Robotic versus laparoscopic surgery for mid-low rectal cancer after neoadjuvant chemoradiation therapy: comparison of oncologic outcomes. Int J Colorectal Dis 28:1689–1698CrossRefPubMed
14.
Zurück zum Zitat Fernandez R, Anaya DA, Li LT et al (2013) Laparoscopic versus robotic rectal resection for rectal cancer in a veteran population. Am J Surg 206:509–517CrossRefPubMed Fernandez R, Anaya DA, Li LT et al (2013) Laparoscopic versus robotic rectal resection for rectal cancer in a veteran population. Am J Surg 206:509–517CrossRefPubMed
15.
Zurück zum Zitat Owens WD, Felts JA, Spitznagel EL Jr (1978) ASA physical status classifications: a study of consistency of ratings. Anesthesiology 49:239–243CrossRefPubMed Owens WD, Felts JA, Spitznagel EL Jr (1978) ASA physical status classifications: a study of consistency of ratings. Anesthesiology 49:239–243CrossRefPubMed
16.
Zurück zum Zitat Balik E, Asoglu O, Saglam S et al (2010) Effects of surgical laparoscopic experience on the short-term postoperative outcome of rectal cancer: results of a high volume single center institution. Surg Laparosc Endosc Percutan Tech 20:93–99CrossRefPubMed Balik E, Asoglu O, Saglam S et al (2010) Effects of surgical laparoscopic experience on the short-term postoperative outcome of rectal cancer: results of a high volume single center institution. Surg Laparosc Endosc Percutan Tech 20:93–99CrossRefPubMed
17.
Zurück zum Zitat Asoglu O, Balik E, Kunduz E et al (2013) Laparoscopic surgery for rectal cancer: outcomes in 513 patients. World J Surg 37:883–892CrossRefPubMed Asoglu O, Balik E, Kunduz E et al (2013) Laparoscopic surgery for rectal cancer: outcomes in 513 patients. World J Surg 37:883–892CrossRefPubMed
18.
Zurück zum Zitat Asoglu O, Kunduz E, Rahmi Serin K et al (2014) Standardized laparoscopic sphincter preserving total mesorectal excision for rectal cancer: long-term oncologic outcome in 217 unselected consecutive patients. Surg Laparosc Endosc Percutan Tech 24:145–152CrossRefPubMed Asoglu O, Kunduz E, Rahmi Serin K et al (2014) Standardized laparoscopic sphincter preserving total mesorectal excision for rectal cancer: long-term oncologic outcome in 217 unselected consecutive patients. Surg Laparosc Endosc Percutan Tech 24:145–152CrossRefPubMed
19.
Zurück zum Zitat Leroy J, Jamali F, Forbes L et al (2004) Laparoscopic total mesorectal excision (TME) for rectal cancer surgery: long-term outcomes. Surg Endosc 18:281–289CrossRefPubMed Leroy J, Jamali F, Forbes L et al (2004) Laparoscopic total mesorectal excision (TME) for rectal cancer surgery: long-term outcomes. Surg Endosc 18:281–289CrossRefPubMed
20.
Zurück zum Zitat Morino M, Parini U, Giraudo G et al (2003) Laparoscopic total mesorectal excision: a consecutive series of 100 patients. Ann Surg 237:335–342PubMedCentralPubMed Morino M, Parini U, Giraudo G et al (2003) Laparoscopic total mesorectal excision: a consecutive series of 100 patients. Ann Surg 237:335–342PubMedCentralPubMed
21.
Zurück zum Zitat Jayne DG, Thorpe HC, Copeland J, Quirke P, Brown JM, Guillou PJ (2010) Five-year follow-up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer. Br J Surg 97:1638–1645CrossRefPubMed Jayne DG, Thorpe HC, Copeland J, Quirke P, Brown JM, Guillou PJ (2010) Five-year follow-up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer. Br J Surg 97:1638–1645CrossRefPubMed
22.
Zurück zum Zitat Xiong B, Ma L, Zhang C, Cheng YJ (2014) Robotic versus laparoscopic total mesorectal excision for rectal cancer: a meta-analysis. Surg Res 188:404–414CrossRef Xiong B, Ma L, Zhang C, Cheng YJ (2014) Robotic versus laparoscopic total mesorectal excision for rectal cancer: a meta-analysis. Surg Res 188:404–414CrossRef
23.
Zurück zum Zitat Rottoli M, Bona S, Rosati R et al (2009) Laparoscopic rectal resection for cancer: effects of conversion on short-term outcome and survival. Ann Surg Oncol 16:1279–1286CrossRefPubMed Rottoli M, Bona S, Rosati R et al (2009) Laparoscopic rectal resection for cancer: effects of conversion on short-term outcome and survival. Ann Surg Oncol 16:1279–1286CrossRefPubMed
24.
Zurück zum Zitat Chan AC, Poon JT, Fan JK, Lo SH, Law WL (2008) Impact of conversion on the long-term outcome in laparoscopic resection of colorectal cancer. Surg Endosc 22:2625–2630CrossRefPubMed Chan AC, Poon JT, Fan JK, Lo SH, Law WL (2008) Impact of conversion on the long-term outcome in laparoscopic resection of colorectal cancer. Surg Endosc 22:2625–2630CrossRefPubMed
25.
Zurück zum Zitat Ptok H, Steinert R, Meyer F et al (2006) Long-term oncological results after laparoscopic, converted, and primary open procedures for rectal carcinoma. Results of a multicenter observational study. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 77:709–717CrossRefPubMed Ptok H, Steinert R, Meyer F et al (2006) Long-term oncological results after laparoscopic, converted, and primary open procedures for rectal carcinoma. Results of a multicenter observational study. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 77:709–717CrossRefPubMed
26.
Zurück zum Zitat Thorpe H, Jayne DG, Guillou PJ, Quirke P, Copeland J, Brown JM (2008) Medical research council conventional versus laparoscopic-assisted surgery in colorectal cancer trial G. Patient factors influencing conversion from laparoscopically assisted to open surgery for colorectal cancer. Br J Surg 95:199–205CrossRefPubMed Thorpe H, Jayne DG, Guillou PJ, Quirke P, Copeland J, Brown JM (2008) Medical research council conventional versus laparoscopic-assisted surgery in colorectal cancer trial G. Patient factors influencing conversion from laparoscopically assisted to open surgery for colorectal cancer. Br J Surg 95:199–205CrossRefPubMed
27.
Zurück zum Zitat Maeso S, Reza M, Mayol J et al (2010) Efficacy of the Da Vinci surgical system in abdominal surgery compared with that of laparoscopy. Ann Surg 252:254–262CrossRefPubMed Maeso S, Reza M, Mayol J et al (2010) Efficacy of the Da Vinci surgical system in abdominal surgery compared with that of laparoscopy. Ann Surg 252:254–262CrossRefPubMed
28.
Zurück zum Zitat Patriti A, Ceccarelli G, Batoli A et al (2009) Short and medium term outcome of robotassisted and traditional laparoscopic rectal resection. JSLS 13:176–183PubMedCentralPubMed Patriti A, Ceccarelli G, Batoli A et al (2009) Short and medium term outcome of robotassisted and traditional laparoscopic rectal resection. JSLS 13:176–183PubMedCentralPubMed
29.
Zurück zum Zitat Ortiz-Oshiro E, Sánchez-Egido I, Moreno-Sierra J, Pérez CF, Díaz JS, Fernández-Represa JÁ (2012) Robotic assistance may reduce conversion to open in rectal carcinoma laparoscopic surgery: systematic review and meta-analysis. Int J Med Robot 8:360–370CrossRefPubMed Ortiz-Oshiro E, Sánchez-Egido I, Moreno-Sierra J, Pérez CF, Díaz JS, Fernández-Represa JÁ (2012) Robotic assistance may reduce conversion to open in rectal carcinoma laparoscopic surgery: systematic review and meta-analysis. Int J Med Robot 8:360–370CrossRefPubMed
30.
Zurück zum Zitat Kelly SB, Mills SJ, Bradburn DM, On behalf of the Northern Region Colorectal Cancer Audit Group et al (2011) Effect of the circumferential resection margin on survival following rectal cancer surgery. Br J Surg 98:573–581CrossRefPubMed Kelly SB, Mills SJ, Bradburn DM, On behalf of the Northern Region Colorectal Cancer Audit Group et al (2011) Effect of the circumferential resection margin on survival following rectal cancer surgery. Br J Surg 98:573–581CrossRefPubMed
31.
Zurück zum Zitat Huang MJ, Liang JL, Wang H et al (2011) Laparoscopic-assisted versus open surgery for rectal cancer: a meta-analysis of randomized controlled trials on oncologic adequacy of resection and long-term oncologic outcomes. Int J Colorectal Dis 26:415–421CrossRefPubMed Huang MJ, Liang JL, Wang H et al (2011) Laparoscopic-assisted versus open surgery for rectal cancer: a meta-analysis of randomized controlled trials on oncologic adequacy of resection and long-term oncologic outcomes. Int J Colorectal Dis 26:415–421CrossRefPubMed
32.
Zurück zum Zitat Quirke P, Dixon MF (1988) The prediction of local recurrence in rectal adenocarcinoma by histopathological examination. Int J Colorectal Dis 3:127–131CrossRefPubMed Quirke P, Dixon MF (1988) The prediction of local recurrence in rectal adenocarcinoma by histopathological examination. Int J Colorectal Dis 3:127–131CrossRefPubMed
33.
Zurück zum Zitat Nagtegaal ID, Marijnen CA, Kranenbarg EK, Pathology Review Committee et al (2002) Cooperative Clinical Investigators Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit. Am J Surg Pathol 26:350–357CrossRefPubMed Nagtegaal ID, Marijnen CA, Kranenbarg EK, Pathology Review Committee et al (2002) Cooperative Clinical Investigators Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit. Am J Surg Pathol 26:350–357CrossRefPubMed
34.
Zurück zum Zitat Anderson C, Uman G, Pigazzi A (2008) Oncologic outcomes of laparoscopic surgery for rectal cancer: a systematic review and meta-analysis of the literature. Eur J Surg Oncol 34:1135–1142CrossRefPubMed Anderson C, Uman G, Pigazzi A (2008) Oncologic outcomes of laparoscopic surgery for rectal cancer: a systematic review and meta-analysis of the literature. Eur J Surg Oncol 34:1135–1142CrossRefPubMed
35.
Zurück zum Zitat van der Pas MH, Haglind E, Cuesta MA, Colorectal Cancer Laparoscopic or Open Resection II (COLOR II) Study Group et al (2013) Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol 14:210–218CrossRefPubMed van der Pas MH, Haglind E, Cuesta MA, Colorectal Cancer Laparoscopic or Open Resection II (COLOR II) Study Group et al (2013) Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol 14:210–218CrossRefPubMed
36.
Zurück zum Zitat Nagtegaal ID, van de Velde CJ, van der Worp E, Kapiteijn E, Quirke P, van Krieken JH (2002) Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. J Clin Oncol 20:1729–1734CrossRefPubMed Nagtegaal ID, van de Velde CJ, van der Worp E, Kapiteijn E, Quirke P, van Krieken JH (2002) Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. J Clin Oncol 20:1729–1734CrossRefPubMed
37.
Zurück zum Zitat Kim JY, Kim NK, Lee KY, Hur H, Min BS, Kim JH (2012) A comparative study of voiding and sexual function after total mesorectal excision with autonomic nerve preservation for rectal cancer: laparoscopic versus robotic surgery. Ann Surg Oncol 19:2485–2493CrossRefPubMed Kim JY, Kim NK, Lee KY, Hur H, Min BS, Kim JH (2012) A comparative study of voiding and sexual function after total mesorectal excision with autonomic nerve preservation for rectal cancer: laparoscopic versus robotic surgery. Ann Surg Oncol 19:2485–2493CrossRefPubMed
38.
Zurück zum Zitat Kwak JM, Kim SH, Kim J, Son DN, Baek SJ, Cho JS (2011) Robotic vs laparoscopic resection of rectal cancer: short-term outcomes of a case-control study. Dis Colon Rectum 54:151–156CrossRefPubMed Kwak JM, Kim SH, Kim J, Son DN, Baek SJ, Cho JS (2011) Robotic vs laparoscopic resection of rectal cancer: short-term outcomes of a case-control study. Dis Colon Rectum 54:151–156CrossRefPubMed
Metadaten
Titel
Robotic versus laparoscopic surgery for mid or low rectal cancer in male patients after neoadjuvant chemoradiation therapy: comparison of short-term outcomes
verfasst von
Kursat Rahmi Serin
Fatma Ayca Gultekin
Burçin Batman
Serden Ay
Yersu Kapran
Sezer Saglam
Oktar Asoglu
Publikationsdatum
01.09.2015
Verlag
Springer London
Erschienen in
Journal of Robotic Surgery / Ausgabe 3/2015
Print ISSN: 1863-2483
Elektronische ISSN: 1863-2491
DOI
https://doi.org/10.1007/s11701-015-0514-3

Weitere Artikel der Ausgabe 3/2015

Journal of Robotic Surgery 3/2015 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.