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Erschienen in:

01.12.2013

Health-related quality of life in survivors of childhood cancer: the role of chronic health problems

verfasst von: Corina S. Rueegg, Micol E. Gianinazzi, Johannes Rischewski, Maja Beck Popovic, Nicolas X. von der Weid, Gisela Michel, Claudia E. Kuehni

Erschienen in: Journal of Cancer Survivorship | Ausgabe 4/2013

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Abstract

Introduction

The influence of specific health problems on health-related quality of life (HRQoL) in childhood cancer survivors is unknown. We compared HRQoL between survivors of childhood cancer and their siblings, determined factors associated with HRQoL, and investigated the influence of chronic health problems on HRQoL.

Methods

Within the Swiss Childhood Cancer Survivor Study, we sent a questionnaire to all survivors (≥16 years) registered in the Swiss Childhood Cancer Registry, who survived >5 years and were diagnosed 1976–2005 aged <16 years. Siblings received similar questionnaires. We assessed HRQoL using Short Form-36 (SF-36). Health problems from a standard questionnaire were classified into overweight, vision impairment, hearing, memory, digestive, musculoskeletal or neurological, and thyroid problems.

Results

The sample included 1,593 survivors and 695 siblings. Survivors scored significantly lower than siblings in physical function, role limitation, general health, and the Physical Component Summary (PCS). Lower score in PCS was associated with a diagnosis of central nervous system tumor, retinoblastoma or bone tumor, having had surgery, cranio-spinal irradiation, or bone marrow transplantation. Lower score in Mental Component Summary was associated with older age. All health problems decreased HRQoL in all scales. Most affected were survivors reporting memory problems and musculoskeletal or neurological problems. Health problems had the biggest impact on physical functioning, general health, and energy and vitality.

Conclusions

In this study, we showed the negative impact of specific chronic health problems on survivors’ HRQoL.

Implications for Cancer Survivors

Therapeutic preventive measures, risk-targeted follow-up, and interventions might help decrease health problems and, consequently, improve survivors’ quality of life.

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Titel: Health-related quality of life in survivors of childhood cancer: the role of chronic health problems
verfasst von: Corina S. Rueegg
Micol E. Gianinazzi
Johannes Rischewski
Maja Beck Popovic
Nicolas X. von der Weid
Gisela Michel
Claudia E. Kuehni
Publikationsdatum: 01.12.2013
Verlag: Springer US
Erschienen in: Journal of Cancer Survivorship / Ausgabe 4/2013
Print ISSN: 1932-2259
Elektronische ISSN: 1932-2267
DOI: https://doi.org/10.1007/s11764-013-0288-4

Neu im Fachgebiet Onkologie

18.04.2024 | Wirbelsäulenmetastase | Nachrichten

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Health-related quality of life in survivors of childhood cancer: the role of chronic health problems

Abstract

Introduction

Methods

Results

Conclusions

Implications for Cancer Survivors

Neu im Fachgebiet Onkologie

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Introduction

Methods

Results

Conclusions

Implications for Cancer Survivors

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