nach oben

Erschienen in:

01.03.2014

Levels of fatigue and distress in senior prostate cancer survivors enrolled in a 12-week randomized controlled trial of Qigong

verfasst von: Rebecca A. Campo, Neeraj Agarwal, Paul C. LaStayo, Kathleen O’Connor, Lisa Pappas, Kenneth M. Boucher, Jerry Gardner, Sierra Smith, Kathleen C. Light, Anita Y. Kinney

Erschienen in: Journal of Cancer Survivorship | Ausgabe 1/2014

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Fatigue is a commonly reported symptom by prostate cancer survivors and is associated with significant distress and declines in quality of life. Qigong is a mind–body activity that consists of both physical activity and meditative aspects. This 12-week randomized controlled trial examined the feasibility and efficacy of a Qigong intervention for improving older prostate cancer survivors' levels of fatigue and distress.

Methods

Forty older (median age = 72, range = 58–93), fatigued (cut-off value of ≥1 on the CTCAEv4.0, >20 on a fatigue grading scale), and sedentary (<150 min of moderate exercise/week) prostate cancer survivors were randomized to 12 weeks of Qigong or stretching classes. Primary outcomes were feasibility (i.e., retention and class attendance rates) and fatigue [Functional Assessment of Chronic Illness Therapy—Fatigue (FACIT-Fatigue)], and secondary outcome was distress [Brief Symptom Inventory-18 (BSI-18)].

Results

Study retention rates did not significantly differ between study groups (Qigong = 80 %, stretching = 65 %, p = 0.48). The Qigong group had significantly higher class attendance than the stretching group (p = 0.04). The Qigong group had significantly greater improvements in the FACIT-Fatigue (p = 0.02) and distress (i.e., BSI-18 Somatization, Anxiety, & Global Severity Index, p's < 0.05), than the Stretching group.

Conclusions

This 12-week Qigong intervention was feasible and potentially efficacious in improving senior prostate cancer survivors' levels of fatigue and distress levels. Future, larger definitive randomized controlled trials are needed to confirm these benefits in older prostate cancer survivors and in racially and ethnically diverse populations.

Implications for cancer survivors

Qigong may be an effective nonpharmacological intervention for the management of senior prostate cancer survivors' fatigue and distress.

Society AC. Cancer facts & figures 2010. Atlanta: American Cancer Society; 2010.

Altekruse SF KC, Krapcho M, Neyman N, Aminou R, Waldron W, Ruhl J, Howlader N, Tatalovich Z, Cho H, Mariotto A, Eisner MP, Lewis DR, Cronin K, Chen HS, Feuer EJ, Stinchcomb DG, Edwards BK. SEER cancer statistics review. National Cancer Institute. 2009. 2011.

Joly F, Alibhai SM, Galica J, Park A, Yi QL, Wagner L, et al. Impact of androgen deprivation therapy on physical and cognitive function, as well as quality of life of patients with nonmetastatic prostate cancer. J Urol. 2006;176(6 Pt 1):2443–7. doi:10.1016/j.juro.2006.07.151.CrossRefPubMed

Rao A, Cohen HJ. Symptom management in the elderly cancer patient: fatigue, pain, and depression. J Natl Cancer Inst Monogr. 2004(32):150–7. doi:10.1093/jncimonographs/lgh031 2004/32/150 [pii].

National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Cancer-Related Fatigue. Version 1.2013. Fort Washington: National Comprehensive Cancer Network; 2012.

Curt GA, Breitbart W, Cella D, Groopman JE, Horning SJ, Itri LM, et al. Impact of cancer-related fatigue on the lives of patients: new findings from the Fatigue Coalition. Oncologist. 2000;5(5):353–60.CrossRefPubMed

Hofman M, Ryan JL, Figueroa-Moseley CD, Jean-Pierre P, Morrow GR. Cancer-related fatigue: the scale of the problem. Oncologist. 2007;12 Suppl 1:4–10. doi:10.1634/theoncologist.12-S1-4.CrossRefPubMed

Rao AV, Demark-Wahnefried W. The older cancer survivor. Crit RevOncolHematol. 2006;60(2):131–43.

Avis NE, Deimling GT. Cancer survivorship and aging. Cancer. 2008;113(12 Suppl):3519–29. doi:10.1002/cncr.23941.CrossRefPubMed

10.

National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Distress Management; 2012.

11.

Ganz PA, Guadagnoli E, Landrum MB, Lash TL, Rakowski W, Silliman RA. Breast cancer in older women: quality of life and psychosocial adjustment in the 15 months after diagnosis. J Clin Oncol. 2003;21(21):4027–33. doi:10.1200/JCO.2003.08.097.CrossRefPubMed

12.

Stanton AL. What happens now? Psychosocial care for cancer survivors after medical treatment completion. J Clin Oncol. 2012;30(11):1215–20. doi:10.1200/JCO.2011.39.7406.CrossRefPubMed

13.

Deimling GT, Bowman KF, Sterns S, Wagner LJ, Kahana B. Cancer-related health worries and psychological distress among older adult, long-term cancer survivors. Psychooncology. 2006;15(4):306–20. doi:10.1002/pon.955.CrossRefPubMed

14.

Mustian KM, Sprod LK, Palesh OG, Peppone LJ, Janelsins MC, Mohile SG, et al. Exercise for the management of side effects and quality of life among cancer survivors. Curr Sports Med Rep. 2009;8(6):325–30. doi:10.1249/JSR.0b013e3181c22324.PubMedCentralCrossRefPubMed

15.

Cramp F, Byron-Daniel J. Exercise for the management of cancer-related fatigue in adults. Cochrane Database Syst Rev. 2012;11, CD006145. doi:10.1002/14651858.CD006145.pub3.PubMed

16.

Puetz TW, Herring MP. Differential effects of exercise on cancer-related fatigue during and following treatment: a meta-analysis. Am J Prev Med. 2012;43(2):e1–e24. doi:10.1016/j.amepre.2012.04.027.CrossRefPubMed

17.

Rogers CE, Larkey LK, Keller C. A review of clinical trials of tai chi and Qigong in older adults. West J Nurs Res. 2009;31(2):245–79. doi:10.1177/0193945908327529.PubMedCentralCrossRefPubMed

18.

Larkey L, Jahnke R, Etnier J, Gonzalez J. Meditative movement as a category of exercise: implications for research. J Phys Act Health. 2009;6(2):230–8.PubMed

19.

Chan CL, Wang CW, Ho RT, Ng SM, Chan JS, Ziea ET, et al. A systematic review of the effectiveness of Qigong exercise in supportive cancer care. Support Care Cancer. 2012;20(6):1121–33. doi:10.1007/s00520-011-1378-3.PubMedCentralCrossRefPubMed

20.

Tsang HW, Tsang WW, Jones AY, Fung KM, Chan AH, Chan EP, et al. Psycho-physical and neurophysiological effects of Qigong on depressed elders with chronic illness. Aging & mental health. 2013;17(3):336–48. doi:10.1080/13607863.2012.732035.CrossRef

21.

Chen Z, Meng Z, Milbury K, Bei W, Zhang Y, Thornton B, et al. Qigong improves quality of life in women undergoing radiotherapy for breast cancer: results of a randomized controlled trial. Cancer. 2013;119:1690–8. doi:10.1002/cncr.27904.CrossRefPubMed

22.

Schulz KF, Altman DG, Moher D. CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. Int J Surg. 2011;9(8):672–7. doi:10.1016/j.ijsu.2011.09.004.CrossRefPubMed

23.

CDC. Fact sheet for health professionals on physical activity guidelines for older adults. Atlanta: US Department of Health and Human Services; 2008.

24.

Hussain M, Tangen CM, Higano C, Schelhammer PF, Faulkner J, Crawford ED, et al. Absolute prostate-specific antigen value after androgen deprivation is a strong independent predictor of survival in new metastatic prostate cancer: data from Southwest Oncology Group Trial 9346 (INT-0162). J Clin Oncol. 2006;24(24):3984–90. doi:10.1200/JCO.2006.06.4246.CrossRefPubMed

25.

Schutzer KA, Graves BS. Barriers and motivations to exercise in older adults. Prev Med. 2004;39(5):1056–61. doi:10.1016/j.ypmed.2004.04.003.CrossRefPubMed

26.

Campo RA, O'Connor K, Light KC, Nakamura Y, Lipschitz DL, Lastayo PC, et al. Feasibility and acceptability of a Tai Chi Chih randomized controlled trial in senior female cancer survivors. Integr Cancer Ther. 2013. doi:10.1177/1534735413485418.PubMedCentralPubMed

27.

Galvao DA, Newton RU. Review of exercise intervention studies in cancer patients. J ClinOncol. 2005;23(4):899–909.CrossRef

28.

LaStayo PC, Marcus RL, Dibble LE, Smith SB, Beck SL. Eccentric exercise versus usual-care with older cancer survivors: the impact on muscle and mobility—an exploratory pilot study. BMC Geriatr. 2011;11:5. doi:10.1186/1471-2318-11-5.PubMedCentralCrossRefPubMed

29.

Cella D, Lai JS, Chang CH, Peterman A, Slavin M. Fatigue in cancer patients compared with fatigue in the general United States population. Cancer. 2002;94(2):528–38. doi:10.1002/cncr.10245.CrossRefPubMed

30.

Derogatis LR. BSI 18 Brief Symptom Inventory 18, administration, scoring, and procedures manual. Minneapolis: NCS Pearson; 2000.

31.

Cella D, Yount S, Sorensen M, Chartash E, Sengupta N, Grober J. Validation of the Functional Assessment of Chronic Illness Therapy Fatigue Scale relative to other instrumentation in patients with rheumatoid arthritis. J Rheumatol. 2005;32(5):811–9.PubMed

32.

Borg GA. Psychophysical bases of perceived exertion. Med Sci Sports Exerc. 1982;14(5):377–81.CrossRefPubMed

33.

Khan CM, Stephens MA, Franks MM, Rook KS, Salem JK. Influences of spousal support and control on diabetes management through physical activity. Health Psychol. 2013;32:739–47. doi:10.1037/a0028609.CrossRefPubMed

34.

Pettee KK, Brach JS, Kriska AM, Boudreau R, Richardson CR, Colbert LH, et al. Influence of marital status on physical activity levels among older adults. Med Sci Sports Exerc. 2006;38(3):541–6. doi:10.1249/01.mss.0000191346.95244.f7.CrossRefPubMed

35.

Oh B, Butow PN, Mullan BA, Clarke SJ, Beale PJ, Pavlakis N, et al. Effect of medical Qigong on cognitive function, quality of life, and a biomarker of inflammation in cancer patients: a randomized controlled trial. Support Care Cancer. 2012;20(6):1235–42. doi:10.1007/s00520-011-1209-6.CrossRefPubMed

36.

Oh B, Butow P, Mullan B, Clarke S, Beale P, Pavlakis N, et al. Impact of medical Qigong on quality of life, fatigue, mood and inflammation in cancer patients: a randomized controlled trial. Ann Oncol. 2010;21(3):608–14. doi:10.1093/annonc/mdp479.PubMedCentralCrossRefPubMed

37.

Ho RT, Chan JS, Wang CW, Lau BW, So KF, Yuen LP, et al. A randomized controlled trial of Qigong exercise on fatigue symptoms, functioning, and telomerase activity in persons with chronic fatigue or chronic fatigue syndrome. Ann Behav Med. 2012;44(2):160–70. doi:10.1007/s12160-012-9381-6.PubMedCentralCrossRefPubMed

38.

Schmitz KH, Courneya KS, Matthews C, Demark-Wahnefried W, Galvao DA, Pinto BM, et al. American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc. 2010;42(7):1409–26. doi:10.1249/MSS.0b013e3181e0c112.CrossRefPubMed

39.

Morey MC, Sloane R, Pieper CF, Peterson MJ, Pearson MP, Ekelund CC, et al. Effect of physical activity guidelines on physical function in older adults. J Am Geriatr Soc. 2008;56(10):1873–8. doi:10.1111/j.1532-5415.2008.01937.x.PubMedCentralCrossRefPubMed

40.

Mohr DC, Spring B, Freedland KE, Beckner V, Arean P, Hollon SD, et al. The selection and design of control conditions for randomized controlled trials of psychological interventions. Psychother Psychosom. 2009;78(5):275–84. doi:10.1159/000228248.CrossRefPubMed

41.

Garland SN, Tamagawa R, Todd SC, Speca M, Carlson LE. Increased mindfulness is related to improved stress and mood following participation in a mindfulness-based stress reduction program in individuals with cancer. Integr Cancer Ther. 2013;12:31–40. doi:10.1177/1534735412442370.CrossRefPubMed

42.

Bower JE, Woolery A, Sternlieb B, Garet D. Yoga for cancer patients and survivors. Cancer Control. 2005;12(3):165–71.PubMed

43.

Singh AA, Jones LW, Antonelli JA, Gerber L, Calloway EE, Shuler KH, et al. Association between exercise and primary incidence of prostate cancer: does race matter? Cancer. 2013;119(7):1338–43. doi:10.1002/cncr.27791.CrossRefPubMed

Titel: Levels of fatigue and distress in senior prostate cancer survivors enrolled in a 12-week randomized controlled trial of Qigong
verfasst von: Rebecca A. Campo
Neeraj Agarwal
Paul C. LaStayo
Kathleen O’Connor
Lisa Pappas
Kenneth M. Boucher
Jerry Gardner
Sierra Smith
Kathleen C. Light
Anita Y. Kinney
Publikationsdatum: 01.03.2014
Verlag: Springer US
Erschienen in: Journal of Cancer Survivorship / Ausgabe 1/2014
Print ISSN: 1932-2259
Elektronische ISSN: 1932-2267
DOI: https://doi.org/10.1007/s11764-013-0315-5

Neu im Fachgebiet Onkologie

23.04.2024 | Medikamente in Schwangerschaft und Stillzeit | Nachrichten

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Levels of fatigue and distress in senior prostate cancer survivors enrolled in a 12-week randomized controlled trial of Qigong

Abstract

Purpose

Methods

Results

Conclusions

Implications for cancer survivors

Neu im Fachgebiet Onkologie

ICI-Therapie in der Schwangerschaft wird gut toleriert

Krebspatienten impfen: Was? Wen? Und wann nicht?

Müde im Alter? Auch an die Nebenniere denken

Stufenschema weist Prostatakarzinom zuverlässig nach

Update Onkologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

Implications for cancer survivors

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2014

Physician visits and preventive care among Asian American and Pacific Islander long-term survivors of colorectal cancer, USA, 1996–2006

African-American breast cancer survivors’ preferences for various types of physical activity interventions: a Sisters Network Inc. web-based survey

Employment following chemoradiotherapy in glioblastoma: a prospective case series

Racial differences in quality of life and employment outcomes in insured women with breast cancer

Emotional well-being years post-treatment for breast cancer: prospective, multi-ethnic, and population-based analysis

Evaluating long-term patient-centered outcomes following prostate cancer treatment: findings from the Michigan Prostate Cancer Survivor study

Neu im Fachgebiet Onkologie

ICI-Therapie in der Schwangerschaft wird gut toleriert

Krebspatienten impfen: Was? Wen? Und wann nicht?

Müde im Alter? Auch an die Nebenniere denken

Stufenschema weist Prostatakarzinom zuverlässig nach

Update Onkologie