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Current Allergy and Asthma Reports

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01.08.2015 | Rhinosinusitis (M Mullol, Section Editor)

Humoral Primary Immunodeficiencies in Chronic Rhinosinusitis

verfasst von: Smriti Nayan, Reza Alizadehfar, Martin Desrosiers

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 8/2015

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Abstract

Chronic rhinosinusitis (CRS) may be the primary presenting symptom for primary immunodeficiencies (PID). PID can affect the humoral or the cellular immune system. This paper provides an overview of PID which affect the humoral immune system, with details around the diagnostic criteria, the epidemiology, the subtypes, the clinical manifestations, underlying molecular mechanisms, methods to screen for PID and the management of CRS in the context of PID. A high clinical suspicion of PID is required when assessing patients with CRS who are refractory to maximal medical therapy.

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Titel: Humoral Primary Immunodeficiencies in Chronic Rhinosinusitis
verfasst von: Smriti Nayan
Reza Alizadehfar
Martin Desrosiers
Publikationsdatum: 01.08.2015
Verlag: Springer US
Erschienen in: Current Allergy and Asthma Reports / Ausgabe 8/2015
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI: https://doi.org/10.1007/s11882-015-0547-8

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Humoral Primary Immunodeficiencies in Chronic Rhinosinusitis

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