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Current Gastroenterology Reports
Erschienen in: Current Gastroenterology Reports 5/2017

01.05.2017 | Small Intestine (D Sachar, Section Editor)

Lactase Non-persistence and Lactose Intolerance

verfasst von: Theodore M. Bayless, Elizabeth Brown, David M. Paige

Erschienen in: Current Gastroenterology Reports | Ausgabe 5/2017

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Abstract

Purpose of Review

To evaluate the clinical and nutritional significance of genetically determined lactase non-persistence and potential lactose and milk intolerance in 65–70% of the world’s adult population.

Recent Findings

Milk consumption is decreasing in the USA and is the lowest in countries with a high prevalence of lactase non-persistence. The dairy industry and Minnesota investigators have made efforts to minimize the influence of lactose intolerance on milk consumption. Some lactose intolerant individuals, without co-existent irritable bowel syndrome, are able to consume a glass of milk with a meal with no or minor symptoms. The high frequency of lactase persistence in offspring of Northern European countries and in some nomadic African tribes is due to mutations in the promoter of the lactase gene in association with survival advantage of milk drinking.

Summary

Educational and commercial efforts to improve calcium and Vitamin D intake have focused on urging consumption of tolerable amounts of milk with a meal, use of lowered lactose-content foods including hard cheeses, yogurt, and lactose-hydrolyzed milk products.
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Metadaten
Titel
Lactase Non-persistence and Lactose Intolerance
verfasst von
Theodore M. Bayless
Elizabeth Brown
David M. Paige
Publikationsdatum
01.05.2017
Verlag
Springer US
Erschienen in
Current Gastroenterology Reports / Ausgabe 5/2017
Print ISSN: 1522-8037
Elektronische ISSN: 1534-312X
DOI
https://doi.org/10.1007/s11894-017-0558-9

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