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Current Hypertension Reports
Erschienen in: Current Hypertension Reports 12/2015

01.12.2015 | Prevention of Hypertension: Public Health Challenges (P Muntner, Section Editor)

Interventions to Improve Medication Adherence in Hypertensive Patients: Systematic Review and Meta-analysis

verfasst von: Vicki S. Conn, Todd M. Ruppar, Jo-Ana D. Chase, Maithe Enriquez, Pamela S. Cooper

Erschienen in: Current Hypertension Reports | Ausgabe 12/2015

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Abstract

This systematic review applied meta-analytic procedures to synthesize medication adherence interventions that focus on adults with hypertension. Comprehensive searching located trials with medication adherence behavior outcomes. Study sample, design, intervention characteristics, and outcomes were coded. Random-effects models were used in calculating standardized mean difference effect sizes. Moderator analyses were conducted using meta-analytic analogues of ANOVA and regression to explore associations between effect sizes and sample, design, and intervention characteristics. Effect sizes were calculated for 112 eligible treatment-vs.-control group outcome comparisons of 34,272 subjects. The overall standardized mean difference effect size between treatment and control subjects was 0.300. Exploratory moderator analyses revealed interventions were most effective among female, older, and moderate- or high-income participants. The most promising intervention components were those linking adherence behavior with habits, giving adherence feedback to patients, self-monitoring of blood pressure, using pill boxes and other special packaging, and motivational interviewing. The most effective interventions employed multiple components and were delivered over many days. Future research should strive for minimizing risks of bias common in this literature, especially avoiding self-report adherence measures.
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Metadaten
Titel
Interventions to Improve Medication Adherence in Hypertensive Patients: Systematic Review and Meta-analysis
verfasst von
Vicki S. Conn
Todd M. Ruppar
Jo-Ana D. Chase
Maithe Enriquez
Pamela S. Cooper
Publikationsdatum
01.12.2015
Verlag
Springer US
Erschienen in
Current Hypertension Reports / Ausgabe 12/2015
Print ISSN: 1522-6417
Elektronische ISSN: 1534-3111
DOI
https://doi.org/10.1007/s11906-015-0606-5

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