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Current Infectious Disease Reports

Erschienen in:

01.09.2010

Early Identification of Sepsis

verfasst von: Mateus Demarchi Gonsalves, Yasser Sakr

Erschienen in: Current Infectious Disease Reports | Ausgabe 5/2010

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Abstract

Early diagnosis is crucial to reduce morbidity and mortality from sepsis. Clinical suspicion is the first step to diagnosis, and necessitates meticulous history taking and complete clinical examination. Special attention should be paid to identifying foci of infection. Biomarkers of host response—including acute phase proteins, procalcitonin, and various cytokines—may be useful in the diagnosis and management of patients with sepsis. Rapid and reliable detection of pathogens and their antibiotic susceptibility patterns is also of utmost importance. Many new techniques have been developed to shorten the time required for pathogen detection, including nucleic acid-based technologies (eg, polymerase chain reaction, microarrays, and hybridization). The detection of pathogen-related antigens is another approach that is useful in the diagnosis of fungal infections, targeting fungal cell wall components such as galactomannan and (1→3)-β-D-glucan.

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Titel: Early Identification of Sepsis
verfasst von: Mateus Demarchi Gonsalves
Yasser Sakr
Publikationsdatum: 01.09.2010
Verlag: Current Science Inc.
Erschienen in: Current Infectious Disease Reports / Ausgabe 5/2010
Print ISSN: 1523-3847
Elektronische ISSN: 1534-3146
DOI: https://doi.org/10.1007/s11908-010-0122-3

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