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Current Osteoporosis Reports

Erschienen in:

01.06.2011

The Role of Bone Marrow and Visceral Fat on Bone Metabolism

verfasst von: Yahtyng Sheu, Jane A. Cauley

Erschienen in: Current Osteoporosis Reports | Ausgabe 2/2011

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Abstract

The protective effect of total fat mass on bone mineral density (BMD) has been challenged with studies showing no or negative association after adjusting for weight. Subsequently, more studies have evaluated the relationship of regional adiposity with BMD, and findings were inconsistent for central obesity. Advancements in imaging techniques enable us to directly and noninvasively study the role of adiposity on skeletal health. Visceral adiposity measured by computed tomography (CT) has consistently been shown to have negative effects on bone. Availability of magnetic resonance spectroscopy (MRS) also allows us to noninvasively quantify bone marrow fat (BMF), which has been known to be associated with osteoporosis from histomorphometric studies. Using MRS along with dual energy x-ray absorptiometry, studies have reported a detrimental role of BMF on BMD. With the increase in aging and obesity of the population, it is important to continue this effort in identifying the contribution of adipose tissues to bone quality and fracture.

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Titel: The Role of Bone Marrow and Visceral Fat on Bone Metabolism
verfasst von: Yahtyng Sheu
Jane A. Cauley
Publikationsdatum: 01.06.2011
Verlag: Current Science Inc.
Erschienen in: Current Osteoporosis Reports / Ausgabe 2/2011
Print ISSN: 1544-1873
Elektronische ISSN: 1544-2241
DOI: https://doi.org/10.1007/s11914-011-0051-6

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