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Current Osteoporosis Reports

Erschienen in:

01.03.2014 | Epidemiology and Pathophysiology (PR Ebeling and EF Eriksen, Section Editors)

Bone Metabolism in Anorexia Nervosa

verfasst von: Pouneh K. Fazeli, Anne Klibanski

Erschienen in: Current Osteoporosis Reports | Ausgabe 1/2014

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Abstract

Anorexia nervosa (AN), a psychiatric disorder predominantly affecting young women, is characterized by self-imposed, chronic nutritional deprivation and distorted body image. AN is associated with a number of medical comorbidities including low bone mass. The low bone mass in AN is due to an uncoupling of bone formation and bone resorption, which is the result of hormonal adaptations aimed at decreasing energy expenditure during periods of low energy intake. Importantly, the low bone mass in AN is associated with a significant risk of fractures and therefore treatments to prevent bone loss are critical. In this review, we discuss the hormonal determinants of low bone mass in AN and treatments that have been investigated in this population.

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Titel: Bone Metabolism in Anorexia Nervosa
verfasst von: Pouneh K. Fazeli
Anne Klibanski
Publikationsdatum: 01.03.2014
Verlag: Springer US
Erschienen in: Current Osteoporosis Reports / Ausgabe 1/2014
Print ISSN: 1544-1873
Elektronische ISSN: 1544-2241
DOI: https://doi.org/10.1007/s11914-013-0186-8

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