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Current Pain and Headache Reports

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01.09.2013 | Neuropathic Pain (E Eisenberg, Section Editor)

Conditioned Pain Modulation: A Predictor for Development and Treatment of Neuropathic Pain

verfasst von: Yelena Granovsky

Erschienen in: Current Pain and Headache Reports | Ausgabe 9/2013

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Abstract

Psychophysical evaluation of endogenous pain inhibition via conditioned pain modulation (CPM) represents a new generation of laboratory tests for pain assessment. In this review we discuss recent findings on CPM in neuropathic pain and refer to psychophysical, neurophysiological, and methodological aspects of its clinical implications. Typically, chronic neuropathic pain patients express less efficient CPM, to the extent that incidence of acquiring neuropathic pain (e.g. post-surgery) and its intensity can be predicted by a pre-surgery CPM assessment. Moreover, pre-treatment CPM evaluation may assist in the correct choice of serotonin-noradrenalin reuptake inhibitor analgesic agents for individual patients. Evaluation of pain modulation capabilities can serve as a step forward in individualizing pain medicine.

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Titel: Conditioned Pain Modulation: A Predictor for Development and Treatment of Neuropathic Pain
verfasst von: Yelena Granovsky
Publikationsdatum: 01.09.2013
Verlag: Springer US
Erschienen in: Current Pain and Headache Reports / Ausgabe 9/2013
Print ISSN: 1531-3433
Elektronische ISSN: 1534-3081
DOI: https://doi.org/10.1007/s11916-013-0361-8

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Conditioned Pain Modulation: A Predictor for Development and Treatment of Neuropathic Pain

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