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Current Pain and Headache Reports
Erschienen in: Current Pain and Headache Reports 10/2015

01.10.2015 | Anesthetic Techniques in Pain Management (D Wang, Section Editor)

Medical Marijuana and Chronic Pain: a Review of Basic Science and Clinical Evidence

verfasst von: Bjorn Jensen, Jeffrey Chen, Tim Furnish, Mark Wallace

Erschienen in: Current Pain and Headache Reports | Ausgabe 10/2015

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Abstract

Cannabinoid compounds include phytocannabinoids, endocannabinoids, and synthetics. The two primary phytocannabinoids are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), with CB1 receptors in the brain and peripheral tissue and CB2 receptors in the immune and hematopoietic systems. The route of delivery of cannabis is important as the bioavailability and metabolism are very different for smoking versus oral/sublingual routes. Gold standard clinical trials are limited; however, some studies have thus far shown evidence to support the use of cannabinoids for some cancer, neuropathic, spasticity, acute pain, and chronic pain conditions.
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Metadaten
Titel
Medical Marijuana and Chronic Pain: a Review of Basic Science and Clinical Evidence
verfasst von
Bjorn Jensen
Jeffrey Chen
Tim Furnish
Mark Wallace
Publikationsdatum
01.10.2015
Verlag
Springer US
Erschienen in
Current Pain and Headache Reports / Ausgabe 10/2015
Print ISSN: 1531-3433
Elektronische ISSN: 1534-3081
DOI
https://doi.org/10.1007/s11916-015-0524-x

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