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Current Psychiatry Reports
Erschienen in: Current Psychiatry Reports 3/2010

01.06.2010

The Impact of Depression in Heart Disease

verfasst von: Yelizaveta Sher, Sermsak Lolak, José R. Maldonado

Erschienen in: Current Psychiatry Reports | Ausgabe 3/2010

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Abstract

Depression and heart disease affect millions of people worldwide. Studies have shown that depression is a significant risk factor for new heart disease and that it increases morbidity and mortality in established heart disease. Many hypothesized and studied mechanisms have linked depression and heart disease, including serotonergic pathway and platelet dysfunction, inflammation, autonomic nervous system and hypothalamic-pituitary-adrenal axis imbalance, and psychosocial factors. Although the treatment of depression in cardiac patients has been shown to be safe and modestly efficacious, it has yet to translate into reduced cardiovascular morbidity and mortality. Understanding the impact and mechanisms behind the association of depression and heart disease may allow for the development of treatments aimed at altering the devastating consequences caused by these comorbid illnesses.
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Metadaten
Titel
The Impact of Depression in Heart Disease
verfasst von
Yelizaveta Sher
Sermsak Lolak
José R. Maldonado
Publikationsdatum
01.06.2010
Verlag
Current Science Inc.
Erschienen in
Current Psychiatry Reports / Ausgabe 3/2010
Print ISSN: 1523-3812
Elektronische ISSN: 1535-1645
DOI
https://doi.org/10.1007/s11920-010-0116-8

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