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Current Rheumatology Reports

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01.08.2012 | PSORIATIC ARTHRITIS (O FITZGERALD AND P HELLIWELL, SECTION EDITORS)

Is Psoriatic Arthritis a Result of Abnormalities in Acquired or Innate Immunity?

verfasst von: Rik J. Lories, Kurt de Vlam

Erschienen in: Current Rheumatology Reports | Ausgabe 4/2012

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Abstract

Psoriatic arthritis is a common chronic inflammatory joint disease in which both inflammation and tissue damage contribute to the patient’s outcome. Abnormal activation of the innate and the adaptive immune system contributes to the chronic disease process. Novel insights into these immune pathways are further corroborated by genetic evidence. In this review, we compare the current paradigm of psoriasis to mechanisms that likely play a role in psoriatic arthritis and provide an overview of the role of immune mechanisms in the different features of the disease.

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Titel: Is Psoriatic Arthritis a Result of Abnormalities in Acquired or Innate Immunity?
verfasst von: Rik J. Lories
Kurt de Vlam
Publikationsdatum: 01.08.2012
Verlag: Current Science Inc.
Erschienen in: Current Rheumatology Reports / Ausgabe 4/2012
Print ISSN: 1523-3774
Elektronische ISSN: 1534-6307
DOI: https://doi.org/10.1007/s11926-012-0257-3

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