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Erschienen in: Clinical Orthopaedics and Related Research® 1/2008

01.01.2008 | Original Article

Obesity is a Major Risk Factor for Prosthetic Infection after Primary Hip Arthroplasty

verfasst von: Michelle M. Dowsey, RN, BApplSc, Peter F. M. Choong, MBBS, MD, FRACS, FAOrthA

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 1/2008

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Abstract

The incidence of obesity and the number of hip arthroplasties being performed in Australia each year are increasing. Although uncommon, periprosthetic infection after surgery can have a devastating effect on patient outcomes. We therefore asked whether obesity correlated with periprosthetic infection after primary hip arthroplasty. We further asked whether variables such as patient comorbidities, operative time, blood transfusions, use of drains, and cementation practices correlated with periprosthetic infection. We hypothesized obesity was an independent risk factor for the development of acute periprosthetic infection after primary hip arthroplasty. We reviewed 1207 consecutive primary hip arthroplasties separating patients into four weight groups, normal, overweight, obese, and morbidly obese, and compared for incidence of periprosthetic infection between the groups. We observed a considerably higher infection rate in obese patients; the correlation was independent of patient comorbidities such as diabetes and cardiovascular disease. We also observed a correlation between infection rates and using a posterior approach in obese patients. The incidence of periprosthetic infection was not influenced by operative time, transfusion requirements, use of drains, and cementation practices. In this series, obesity was an independent risk factor for acute periprosthetic infection after primary hip arthroplasty.
Level of Evidence: Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.
Literatur
3.
Zurück zum Zitat Baker AS, Bitounis VC. Abductor function after total hip replacement: an electromyographic and clinical review. J Bone Joint Surg Br. 1989;71:47–50.PubMed Baker AS, Bitounis VC. Abductor function after total hip replacement: an electromyographic and clinical review. J Bone Joint Surg Br. 1989;71:47–50.PubMed
4.
Zurück zum Zitat Barber TC, Roger DJ, Goodman SB, Schurman DJ. Early outcome of total hip arthroplasty using the direct lateral vs the posterior surgical approach. Orthopedics. 1996;19:873–875.PubMed Barber TC, Roger DJ, Goodman SB, Schurman DJ. Early outcome of total hip arthroplasty using the direct lateral vs the posterior surgical approach. Orthopedics. 1996;19:873–875.PubMed
5.
Zurück zum Zitat Borghi B, Casati A. Incidence and risk factors for allogenic blood transfusion during major joint replacement using an integrated autotransfusion regimen. The Rizzoli Study Group on Orthopaedic Anaesthesia. Eur J Anaesthesiol. 2000;17:411–417.PubMedCrossRef Borghi B, Casati A. Incidence and risk factors for allogenic blood transfusion during major joint replacement using an integrated autotransfusion regimen. The Rizzoli Study Group on Orthopaedic Anaesthesia. Eur J Anaesthesiol. 2000;17:411–417.PubMedCrossRef
6.
Zurück zum Zitat Böstman OM. Prevalence of obesity among patients admitted for elective orthopaedic surgery. Int J Obes Relat Metab Disord. 1994;18:709–713.PubMed Böstman OM. Prevalence of obesity among patients admitted for elective orthopaedic surgery. Int J Obes Relat Metab Disord. 1994;18:709–713.PubMed
8.
Zurück zum Zitat Chan CL, Villar RN. Obesity and quality of life after primary hip arthroplasty. J Bone Joint Surg Br. 1996;78:78–81.PubMed Chan CL, Villar RN. Obesity and quality of life after primary hip arthroplasty. J Bone Joint Surg Br. 1996;78:78–81.PubMed
9.
Zurück zum Zitat Choong PF, Dowsey MM, Carr D, Daffy J, Stanley P. Risk factors associated with acute hip prosthetic joint infections and outcome of treatment with rifampin-based regimen. Acta Orthop, in press. Choong PF, Dowsey MM, Carr D, Daffy J, Stanley P. Risk factors associated with acute hip prosthetic joint infections and outcome of treatment with rifampin-based regimen. Acta Orthop, in press.
10.
Zurück zum Zitat Cooper C, Inskip H, Croft P, Campbell L, Smith G, McLaren M, Coggon D. Individual risk factors for hip osteoarthritis: obesity, hip injury, and physical activity. Am J Epidemiol. 1998;147:516–522.PubMed Cooper C, Inskip H, Croft P, Campbell L, Smith G, McLaren M, Coggon D. Individual risk factors for hip osteoarthritis: obesity, hip injury, and physical activity. Am J Epidemiol. 1998;147:516–522.PubMed
11.
Zurück zum Zitat Downing ND, Clark DI, Hutchinson JW, Colclough K, Howard PW. Hip abductor strength following total hip arthroplasty: a prospective comparison of the posterior and lateral approach in 100 patients. Acta Orthop Scand. 2001;72:215–220.PubMedCrossRef Downing ND, Clark DI, Hutchinson JW, Colclough K, Howard PW. Hip abductor strength following total hip arthroplasty: a prospective comparison of the posterior and lateral approach in 100 patients. Acta Orthop Scand. 2001;72:215–220.PubMedCrossRef
12.
Zurück zum Zitat Engesaeter LB, Espehaug B, Lie SA, Furnes O, Havelin LI. Does cement increase the risk of infection in primary total hip arthroplasty? Revision rates in 56,275 cemented and uncemented primary THAs followed for 0–16 years in the Norwegian Arthroplasty Register. Acta Orthop. 2006;77:351–358.PubMedCrossRef Engesaeter LB, Espehaug B, Lie SA, Furnes O, Havelin LI. Does cement increase the risk of infection in primary total hip arthroplasty? Revision rates in 56,275 cemented and uncemented primary THAs followed for 0–16 years in the Norwegian Arthroplasty Register. Acta Orthop. 2006;77:351–358.PubMedCrossRef
13.
Zurück zum Zitat Fitzgerald RH Jr, Nolan DR, Ilstrup DM, Van Scoy RE, Washington JA 2nd, Coventry MB. Deep wound sepsis following total hip arthroplasty. J Bone Joint Surg Am. 1977;59:847–855.PubMed Fitzgerald RH Jr, Nolan DR, Ilstrup DM, Van Scoy RE, Washington JA 2nd, Coventry MB. Deep wound sepsis following total hip arthroplasty. J Bone Joint Surg Am. 1977;59:847–855.PubMed
14.
Zurück zum Zitat Garibaldi RA, Cushing D, Lerer T. Risk factors for postoperative infection. Am J Med. 1991;91:158S–163S.PubMedCrossRef Garibaldi RA, Cushing D, Lerer T. Risk factors for postoperative infection. Am J Med. 1991;91:158S–163S.PubMedCrossRef
15.
Zurück zum Zitat Garrow JS, Webster J. Quetelet’s index (W/H2) as a measure of fatness. Int J Obes. 1985;9:147–153.PubMed Garrow JS, Webster J. Quetelet’s index (W/H2) as a measure of fatness. Int J Obes. 1985;9:147–153.PubMed
16.
17.
Zurück zum Zitat Ilstrup DM, Nolan DR, Beckenbaugh RD, Coventry MB. Factors influencing the results in 2,012 total hip arthroplasties. Clin Orthop Relat Res. 1973;95:250–262.PubMed Ilstrup DM, Nolan DR, Beckenbaugh RD, Coventry MB. Factors influencing the results in 2,012 total hip arthroplasties. Clin Orthop Relat Res. 1973;95:250–262.PubMed
18.
Zurück zum Zitat Innerhofer P, Klingler A, Klimmer C, Fries D, Nussbaumer W. Risk for postoperative infection after transfusion of white blood cell-filtered allogeneic or autologous blood components in orthopedic patients undergoing primary arthroplasty. Transfusion. 2005;45:103–110.PubMedCrossRef Innerhofer P, Klingler A, Klimmer C, Fries D, Nussbaumer W. Risk for postoperative infection after transfusion of white blood cell-filtered allogeneic or autologous blood components in orthopedic patients undergoing primary arthroplasty. Transfusion. 2005;45:103–110.PubMedCrossRef
19.
Zurück zum Zitat Jain NB, Guller U, Pietrobon R, Bond TK, Higgins LD. Comorbidities increase complication rates in patients having arthroplasty. Clin Orthop Relat Res. 2005;435:232–238.PubMedCrossRef Jain NB, Guller U, Pietrobon R, Bond TK, Higgins LD. Comorbidities increase complication rates in patients having arthroplasty. Clin Orthop Relat Res. 2005;435:232–238.PubMedCrossRef
20.
Zurück zum Zitat Jain SA, Roach RT, Travlos J. Changes in body mass index following primary elective total hip arthroplasty: correlation with outcome at 2 years. Acta Orthop Belg. 2003;69:421–425.PubMed Jain SA, Roach RT, Travlos J. Changes in body mass index following primary elective total hip arthroplasty: correlation with outcome at 2 years. Acta Orthop Belg. 2003;69:421–425.PubMed
21.
Zurück zum Zitat Jolles BM, Bogoch ER. Posterior versus lateral surgical approach for total hip arthroplasty in adults with osteoarthritis. Cochrane Database Syst Rev. 2006;3:CD003828.PubMed Jolles BM, Bogoch ER. Posterior versus lateral surgical approach for total hip arthroplasty in adults with osteoarthritis. Cochrane Database Syst Rev. 2006;3:CD003828.PubMed
22.
Zurück zum Zitat Karlson EW, Mandl LA, Aweh GN, Sangha O, Liang MH, Grodstein F. Total hip replacement due to osteoarthritis: the importance of age, obesity, and other modifiable risk factors. Am J Med. 2003;114:93–98.PubMedCrossRef Karlson EW, Mandl LA, Aweh GN, Sangha O, Liang MH, Grodstein F. Total hip replacement due to osteoarthritis: the importance of age, obesity, and other modifiable risk factors. Am J Med. 2003;114:93–98.PubMedCrossRef
23.
Zurück zum Zitat Knutsson S, Engberg IB. An evaluation of patients’ quality of life before, 6 weeks and 6 months after total hip replacement surgery. J Adv Nurs. 1999;30:1349–1359.PubMedCrossRef Knutsson S, Engberg IB. An evaluation of patients’ quality of life before, 6 weeks and 6 months after total hip replacement surgery. J Adv Nurs. 1999;30:1349–1359.PubMedCrossRef
24.
Zurück zum Zitat Lehman DE, Capello WN, Feinberg JR. Total hip arthroplasty without cement in obese patients: a minimum two-year clinical and radiographic follow-up study. J Bone Joint Surg Am. 1994;76:854–862.PubMed Lehman DE, Capello WN, Feinberg JR. Total hip arthroplasty without cement in obese patients: a minimum two-year clinical and radiographic follow-up study. J Bone Joint Surg Am. 1994;76:854–862.PubMed
25.
Zurück zum Zitat Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol. 1999;20:250–278; quiz 279–280.PubMedCrossRef Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol. 1999;20:250–278; quiz 279–280.PubMedCrossRef
26.
Zurück zum Zitat Mantilla CB, Horlocker TT, Schroeder DR, Berry DJ, Brown DL. Risk factors for clinically relevant pulmonary embolism and deep venous thrombosis in patients undergoing primary hip or knee arthroplasty. Anesthesiology. 2003;99:552–560; discussion 555A.PubMedCrossRef Mantilla CB, Horlocker TT, Schroeder DR, Berry DJ, Brown DL. Risk factors for clinically relevant pulmonary embolism and deep venous thrombosis in patients undergoing primary hip or knee arthroplasty. Anesthesiology. 2003;99:552–560; discussion 555A.PubMedCrossRef
27.
Zurück zum Zitat Marks R, Allegrante JP. Body mass indices in patients with disabling hip osteoarthritis. Arthritis Res. 2002;4:112–116.PubMedCrossRef Marks R, Allegrante JP. Body mass indices in patients with disabling hip osteoarthritis. Arthritis Res. 2002;4:112–116.PubMedCrossRef
28.
Zurück zum Zitat McLaughlin JR, Lee KR. The outcome of total hip replacement in obese and non-obese patients at 10- to 18-years. J Bone Joint Surg Br. 2006;88:1286–1292.PubMedCrossRef McLaughlin JR, Lee KR. The outcome of total hip replacement in obese and non-obese patients at 10- to 18-years. J Bone Joint Surg Br. 2006;88:1286–1292.PubMedCrossRef
29.
Zurück zum Zitat Moran M, Walmsley P, Gray A, Brenkel IJ. Does body mass index affect the early outcome of primary total hip arthroplasty? J Arthroplasty. 2005;20:866–869.PubMedCrossRef Moran M, Walmsley P, Gray A, Brenkel IJ. Does body mass index affect the early outcome of primary total hip arthroplasty? J Arthroplasty. 2005;20:866–869.PubMedCrossRef
30.
Zurück zum Zitat Namba RS, Paxton L, Fithian DC, Stone ML. Obesity and perioperative morbidity in total hip and total knee arthroplasty patients. J Arthroplasty. 2005;20(7 suppl 3):46–50.PubMedCrossRef Namba RS, Paxton L, Fithian DC, Stone ML. Obesity and perioperative morbidity in total hip and total knee arthroplasty patients. J Arthroplasty. 2005;20(7 suppl 3):46–50.PubMedCrossRef
31.
Zurück zum Zitat Proietto J, Baur LA. 10: Management of obesity. Med J Aust. 2004;180:474–480.PubMed Proietto J, Baur LA. 10: Management of obesity. Med J Aust. 2004;180:474–480.PubMed
32.
Zurück zum Zitat Rosencher N, Kerkkamp HE, Macheras G, Munuera LM, Menichella G, Barton DM, Cremers S, Abraham IL. Orthopedic Surgery Transfusion Hemoglobin European Overview (OSTHEO) study: blood management in elective knee and hip arthroplasty in Europe. Transfusion. 2003;43:459–469.PubMedCrossRef Rosencher N, Kerkkamp HE, Macheras G, Munuera LM, Menichella G, Barton DM, Cremers S, Abraham IL. Orthopedic Surgery Transfusion Hemoglobin European Overview (OSTHEO) study: blood management in elective knee and hip arthroplasty in Europe. Transfusion. 2003;43:459–469.PubMedCrossRef
33.
Zurück zum Zitat Sadr Azodi O, Bellocco R, Eriksson K, Adami J. The impact of tobacco use and body mass index on the length of stay in hospital and the risk of post-operative complications among patients undergoing total hip replacement. J Bone Joint Surg Br. 2006;88:1316–1320.PubMedCrossRef Sadr Azodi O, Bellocco R, Eriksson K, Adami J. The impact of tobacco use and body mass index on the length of stay in hospital and the risk of post-operative complications among patients undergoing total hip replacement. J Bone Joint Surg Br. 2006;88:1316–1320.PubMedCrossRef
34.
Zurück zum Zitat Saleh K, Olson M, Resig S, Bershadsky B, Kuskowski M, Gioe T, Robinson H, Schmidt R, McElfresh E. Predictors of wound infection in hip and knee joint replacement: results from a 20 year surveillance program. J Orthop Res. 2002;20:506–515.PubMedCrossRef Saleh K, Olson M, Resig S, Bershadsky B, Kuskowski M, Gioe T, Robinson H, Schmidt R, McElfresh E. Predictors of wound infection in hip and knee joint replacement: results from a 20 year surveillance program. J Orthop Res. 2002;20:506–515.PubMedCrossRef
35.
Zurück zum Zitat Sitges-Serra A, Insenser JJ, Membrilla E. Blood transfusions and postoperative infections in patients undergoing elective surgery. Surg Infect (Larchmt). 2006;7(suppl 2):S33–S35. Sitges-Serra A, Insenser JJ, Membrilla E. Blood transfusions and postoperative infections in patients undergoing elective surgery. Surg Infect (Larchmt). 2006;7(suppl 2):S33–S35.
36.
Zurück zum Zitat Stickles B, Phillips L, Brox WT, Owens B, Lanzer WL. Defining the relationship between obesity and total joint arthroplasty. Obes Res. 2001;9:219–223.PubMedCrossRef Stickles B, Phillips L, Brox WT, Owens B, Lanzer WL. Defining the relationship between obesity and total joint arthroplasty. Obes Res. 2001;9:219–223.PubMedCrossRef
37.
Zurück zum Zitat Walmsley PJ, Kelly MB, Hill RM, Brenkel I. A prospective, randomised, controlled trial of the use of drains in total hip arthroplasty. J Bone Joint Surg Br. 2005;87:1397–1401.PubMedCrossRef Walmsley PJ, Kelly MB, Hill RM, Brenkel I. A prospective, randomised, controlled trial of the use of drains in total hip arthroplasty. J Bone Joint Surg Br. 2005;87:1397–1401.PubMedCrossRef
38.
Zurück zum Zitat Weale AE, Newman P, Ferguson IT, Bannister GC. Nerve injury after posterior and direct lateral approaches for hip replacement: a clinical and electrophysiological study. J Bone Joint Surg Br. 1996;78:899–902.PubMedCrossRef Weale AE, Newman P, Ferguson IT, Bannister GC. Nerve injury after posterior and direct lateral approaches for hip replacement: a clinical and electrophysiological study. J Bone Joint Surg Br. 1996;78:899–902.PubMedCrossRef
Metadaten
Titel
Obesity is a Major Risk Factor for Prosthetic Infection after Primary Hip Arthroplasty
verfasst von
Michelle M. Dowsey, RN, BApplSc
Peter F. M. Choong, MBBS, MD, FRACS, FAOrthA
Publikationsdatum
01.01.2008
Verlag
Springer-Verlag
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 1/2008
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-007-0016-3

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