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Erschienen in: Clinical Orthopaedics and Related Research® 10/2008

01.10.2008 | Original Article

Unicameral Bone Cyst: A Retrospective Study of Three Surgical Treatments

verfasst von: Anthony D. Sung, BS, Megan E. Anderson, MD, David Zurakowski, PhD, Francis J. Hornicek, MD, PhD, Mark C. Gebhardt, MD

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 10/2008

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Abstract

Between 1979 and 2004, 167 patients younger than 20 years were treated surgically for humeral or femoral unicameral bone cysts with either injection of corticosteroids (steroids), curettage plus bone grafting (curettage), or a combination injection of steroids, demineralized bone matrix, and bone marrow aspirate (SDB) at Children’s Hospital of Boston and Massachusetts General Hospital (mean followup, 7.3 years; range, 1 month–27 years). Outcomes included treatment failure (defined clinically as subsequent pathologic fracture or need for retreatment to prevent pathologic fracture) and complications. Information was obtained from medical records and by telephone questionnaire. After one treatment, 84% of cysts treated with steroids experienced failed treatment versus 64% with curettage and 50% with SDB. For unicameral bone cysts requiring retreatment (regardless of first treatment), 76% retreated with steroids had failed treatment versus 63% with curettage and 71% with SDB. Curettage was associated with the lowest rate of posttreatment pathologic fractures and highest rate of pain and other complications. Multivariate logistic regression indicated treatment with steroids alone and younger age were independent predictors of failure. We believe SDB is a reasonable first treatment for unicameral bone cysts in the humerus and femur in patients younger than 20 years, being less invasive yet comparable to curettage in preventing recurrence.
Level of Evidence: Level IV, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.
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Metadaten
Titel
Unicameral Bone Cyst: A Retrospective Study of Three Surgical Treatments
verfasst von
Anthony D. Sung, BS
Megan E. Anderson, MD
David Zurakowski, PhD
Francis J. Hornicek, MD, PhD
Mark C. Gebhardt, MD
Publikationsdatum
01.10.2008
Verlag
Springer-Verlag
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 10/2008
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-008-0407-0

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