Erschienen in:
01.01.2009 | Symposium: Papers Presented at the Hip Society Meetings 2008
2008 John Charnley Award: Metal Ion Levels After Metal-on-Metal Total Hip Arthroplasty: A Randomized Trial
verfasst von:
C. Anderson Engh Jr., MD, Steven J. MacDonald, MD, Supatra Sritulanondha, MPH, Abigail Thompson, RN, Douglas Naudie, MD, Charles A. Engh, MD
Erschienen in:
Clinical Orthopaedics and Related Research®
|
Ausgabe 1/2009
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Abstract
Metal-on-metal bearing total hip arthroplasty is performed more commonly than in the past. There may be manufacturing differences such as clearance, roughness, metallurgy, and head size that affect performance. In a prospective, randomized trial, we compared 2-year postoperative ion levels for a 28-mm metal-on-polyethylene bearing with 28-mm and 36-mm metal-on-metal bearings. We measured serum, erythrocyte, and urine ion levels. We observed no difference in the ion levels for the 28-mm and 36-mm metal-on-metal bearings. The ion levels in these patients were lower than reported for most other metal-on-metal bearings. Although both erythrocyte and serum cobalt increased, erythrocyte chromium and erythrocyte titanium did not increase despite a four- to sixfold serum chromium and a three- to fourfold serum titanium increase. This may represent a threshold level for serum chromium and serum titanium below which erythrocytes are not affected.
Level of Evidence: Level I, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.