Skip to main content
Erschienen in: Clinical Orthopaedics and Related Research® 5/2009

01.05.2009 | Symposium: Clubfoot: Etiology and Treatment

Update on Clubfoot: Etiology and Treatment

verfasst von: Matthew B. Dobbs, MD, Christina A. Gurnett, MD, PhD

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 5/2009

Einloggen, um Zugang zu erhalten

Abstract

Although clubfoot is one of the most common congenital abnormalities affecting the lower limb, it remains a challenge not only to understand its genetic origins but also to provide effective long-term treatment. This review provides an update on the etiology of clubfoot as well as current treatment strategies. Understanding the exact genetic etiology of clubfoot may eventually be helpful in determining both prognosis and the selection of appropriate treatment methods in individual patients. The primary treatment goal is to provide long-term correction with a foot that is fully functional and pain-free. To achieve this, a combination of approaches that applies the strengths of several methods (Ponseti method and French method) may be needed. Avoidance of extensive soft-tissue release operations in the primary treatment should be a priority, and the use of surgery for clubfoot correction should be limited to an “a la carte” mode and only after failed conservative methods.
Level of Evidence: Level V, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
Literatur
1.
Zurück zum Zitat Aronson J, Puskarich CL. Deformity and disability from treated clubfoot. J Pediatr Orthop. 1990;10:109–119.PubMed Aronson J, Puskarich CL. Deformity and disability from treated clubfoot. J Pediatr Orthop. 1990;10:109–119.PubMed
2.
Zurück zum Zitat Atar D, Lehman WB, Grant AD. Complications in clubfoot surgery. Orthop Rev. 1991;20:233–239.PubMed Atar D, Lehman WB, Grant AD. Complications in clubfoot surgery. Orthop Rev. 1991;20:233–239.PubMed
3.
Zurück zum Zitat Bakalis S, Sairam S, Homfray T, Harrington K, Nicolaides K, Thilaganathan B. Outcome of antenatally diagnosed talipes equinovarus in an unselected obstetric population. Ultrasound Obstet Gynecol. 2002;20:226–229.PubMedCrossRef Bakalis S, Sairam S, Homfray T, Harrington K, Nicolaides K, Thilaganathan B. Outcome of antenatally diagnosed talipes equinovarus in an unselected obstetric population. Ultrasound Obstet Gynecol. 2002;20:226–229.PubMedCrossRef
4.
Zurück zum Zitat Barker SL, Lavy CB. Correlation of clinical and ultrasonographic findings after Achilles tenotomy in idiopathic club foot. J Bone Joint Surg Br. 2006;88:377–379.PubMedCrossRef Barker SL, Lavy CB. Correlation of clinical and ultrasonographic findings after Achilles tenotomy in idiopathic club foot. J Bone Joint Surg Br. 2006;88:377–379.PubMedCrossRef
5.
Zurück zum Zitat Beals RK. Club foot in the Maori: a genetic study of 50 kindreds. N Z Med J. 1978;88:144–146.PubMed Beals RK. Club foot in the Maori: a genetic study of 50 kindreds. N Z Med J. 1978;88:144–146.PubMed
6.
Zurück zum Zitat Bensahel H, Catterall A, Dimeglio A. Practical applications in idiopathic clubfoot: a retrospective multicentric study in EPOS. J Pediatr Orthop. 1990;10:186–188.PubMed Bensahel H, Catterall A, Dimeglio A. Practical applications in idiopathic clubfoot: a retrospective multicentric study in EPOS. J Pediatr Orthop. 1990;10:186–188.PubMed
7.
Zurück zum Zitat Bensahel H, Csukonyi Z, Desgrippes Y, Chaumien JP. Surgery in residual clubfoot: one-stage medioposterior release “a la carte”. J Pediatr Orthop. 1987;7:145–148.PubMed Bensahel H, Csukonyi Z, Desgrippes Y, Chaumien JP. Surgery in residual clubfoot: one-stage medioposterior release “a la carte”. J Pediatr Orthop. 1987;7:145–148.PubMed
8.
Zurück zum Zitat Boehm S, Limpaphayom N, Alaee F, Sinclair MF, Dobbs MB. Early results of the Ponseti method for the treatment of clubfoot in distal arthrogryposis. J Bone Joint Surg Am. 2008;90:1501–1507.PubMedCrossRef Boehm S, Limpaphayom N, Alaee F, Sinclair MF, Dobbs MB. Early results of the Ponseti method for the treatment of clubfoot in distal arthrogryposis. J Bone Joint Surg Am. 2008;90:1501–1507.PubMedCrossRef
9.
Zurück zum Zitat Bonnell J, Cruess RL. Anomalous insertion of the soleus muscle as a cause of fixed equinus deformity. A case report. J Bone Joint Surg Am. 1969;51:999–1000.PubMed Bonnell J, Cruess RL. Anomalous insertion of the soleus muscle as a cause of fixed equinus deformity. A case report. J Bone Joint Surg Am. 1969;51:999–1000.PubMed
10.
Zurück zum Zitat Changulani M, Garg NK, Rajagopal TS, Bass A, Nayagam SN, Sampath J, Bruce CE. Treatment of idiopathic club foot using the Ponseti method. Initial experience. J Bone Joint Surg Br. 2006;88:1385–1387.PubMed Changulani M, Garg NK, Rajagopal TS, Bass A, Nayagam SN, Sampath J, Bruce CE. Treatment of idiopathic club foot using the Ponseti method. Initial experience. J Bone Joint Surg Br. 2006;88:1385–1387.PubMed
11.
Zurück zum Zitat Chapman C, Stott NS, Port RV, Nicol RO. Genetics of club foot in Maori and Pacific people. J Med Genet. 2000;37:680–683.PubMedCrossRef Chapman C, Stott NS, Port RV, Nicol RO. Genetics of club foot in Maori and Pacific people. J Med Genet. 2000;37:680–683.PubMedCrossRef
12.
Zurück zum Zitat Chen RC, Gordon JE, Luhmann SJ, Schoenecker PL, Dobbs MB. A new dynamic foot abduction orthosis for clubfoot treatment. J Pediatr Orthop. 2007;27:522–528.PubMed Chen RC, Gordon JE, Luhmann SJ, Schoenecker PL, Dobbs MB. A new dynamic foot abduction orthosis for clubfoot treatment. J Pediatr Orthop. 2007;27:522–528.PubMed
13.
Zurück zum Zitat Chung CS, Nemechek RW, Larsen IJ, Ching GH. Genetic and epidemiological studies of clubfoot in Hawaii. General and medical considerations. Hum Hered. 1969;19:321–342.PubMedCrossRef Chung CS, Nemechek RW, Larsen IJ, Ching GH. Genetic and epidemiological studies of clubfoot in Hawaii. General and medical considerations. Hum Hered. 1969;19:321–342.PubMedCrossRef
14.
Zurück zum Zitat Cooper DM, Dietz FR. Treatment of idiopathic clubfoot. A thirty-year follow-up note. J Bone Joint Surg Am. 1995;77:1477–1489.PubMed Cooper DM, Dietz FR. Treatment of idiopathic clubfoot. A thirty-year follow-up note. J Bone Joint Surg Am. 1995;77:1477–1489.PubMed
15.
Zurück zum Zitat Coss HS, Hennrikus WL. Parent satisfaction comparing two bandage materials used during serial casting in infants. Foot Ankle Int. 1996;17:483–486.PubMed Coss HS, Hennrikus WL. Parent satisfaction comparing two bandage materials used during serial casting in infants. Foot Ankle Int. 1996;17:483–486.PubMed
16.
Zurück zum Zitat de Andrade M, Barnholtz JS, Amos CI, Lochmiller C, Scott A, Risman M, Hecht JT. Segregation analysis of idiopathic talipes equinovarus in a Texan population. Am J Med Genet. 1998;79:97–102.PubMedCrossRef de Andrade M, Barnholtz JS, Amos CI, Lochmiller C, Scott A, Risman M, Hecht JT. Segregation analysis of idiopathic talipes equinovarus in a Texan population. Am J Med Genet. 1998;79:97–102.PubMedCrossRef
17.
Zurück zum Zitat Dimeglio A, Bensahel H, Souchet P, Mazeau P, Bonnet F. Classification of clubfoot. J Pediatr Orthop B. 1995;4:129–136.PubMed Dimeglio A, Bensahel H, Souchet P, Mazeau P, Bonnet F. Classification of clubfoot. J Pediatr Orthop B. 1995;4:129–136.PubMed
18.
Zurück zum Zitat Dimeglio A, Bonnet F, Mazeau P, De Rosa V. Orthopaedic treatment and passive motion machine: consequences for the surgical treatment of clubfoot. J Pediatr Orthop B. 1996;5:173–180.PubMed Dimeglio A, Bonnet F, Mazeau P, De Rosa V. Orthopaedic treatment and passive motion machine: consequences for the surgical treatment of clubfoot. J Pediatr Orthop B. 1996;5:173–180.PubMed
19.
Zurück zum Zitat Dobbs MB, Gordon JE, Walton T, Schoenecker PL. Bleeding complications following percutaneous tendoachilles tenotomy in the treatment of clubfoot deformity. J Pediatr Orthop. 2004;24:353–357.PubMed Dobbs MB, Gordon JE, Walton T, Schoenecker PL. Bleeding complications following percutaneous tendoachilles tenotomy in the treatment of clubfoot deformity. J Pediatr Orthop. 2004;24:353–357.PubMed
20.
Zurück zum Zitat Dobbs MB, Morcuende JA, Gurnett CA, Ponseti IV. Treatment of idiopathic clubfoot: an historical review. Iowa Orthop J. 2000;20:59–64.PubMed Dobbs MB, Morcuende JA, Gurnett CA, Ponseti IV. Treatment of idiopathic clubfoot: an historical review. Iowa Orthop J. 2000;20:59–64.PubMed
21.
Zurück zum Zitat Dobbs MB, Nunley R, Schoenecker PL. Long-term follow-up of patients with clubfeet treated with extensive soft-tissue release. J Bone Joint Surg Am. 2006;88:986–996.PubMedCrossRef Dobbs MB, Nunley R, Schoenecker PL. Long-term follow-up of patients with clubfeet treated with extensive soft-tissue release. J Bone Joint Surg Am. 2006;88:986–996.PubMedCrossRef
22.
Zurück zum Zitat Dobbs MB, Rudzki JR, Purcell DB, Walton T, Porter KR, Gurnett CA. Factors predictive of outcome after use of the Ponseti method for the treatment of idiopathic clubfeet. J Bone Joint Surg Am. 2004;86:22–27.PubMed Dobbs MB, Rudzki JR, Purcell DB, Walton T, Porter KR, Gurnett CA. Factors predictive of outcome after use of the Ponseti method for the treatment of idiopathic clubfeet. J Bone Joint Surg Am. 2004;86:22–27.PubMed
23.
Zurück zum Zitat Dunn PM. Congenital postural deformities: perinatal associations. Proc R Soc Med. 1972;65:735–738.PubMed Dunn PM. Congenital postural deformities: perinatal associations. Proc R Soc Med. 1972;65:735–738.PubMed
24.
Zurück zum Zitat Elmslie RC. The principles of treatment of congenital talipes equinovarus. J. Orthop Surg. 1920;2:669. Elmslie RC. The principles of treatment of congenital talipes equinovarus. J. Orthop Surg. 1920;2:669.
25.
Zurück zum Zitat Flynn JM, Donohoe M, Mackenzie WG. An independent assessment of two clubfoot-classification systems. J Pediatr Orthop. 1998;18:323–327.PubMedCrossRef Flynn JM, Donohoe M, Mackenzie WG. An independent assessment of two clubfoot-classification systems. J Pediatr Orthop. 1998;18:323–327.PubMedCrossRef
26.
Zurück zum Zitat Garg S, Dobbs MB. Use of the Ponseti method for recurrent clubfoot following posteromedial release. Indian J Orthop. 2008;42:68–72.CrossRefPubMed Garg S, Dobbs MB. Use of the Ponseti method for recurrent clubfoot following posteromedial release. Indian J Orthop. 2008;42:68–72.CrossRefPubMed
28.
Zurück zum Zitat Gurnett CA, Alaee F, Kruse LM, Desruisseau DM, Hecht JT, Wise CA, Bowcock AM, Dobbs MB. Asymmetric lower-limb malformations in individuals with homeobox PITX1 gene mutation. Am J Hum Genet. 2008;83:616–622.PubMedCrossRef Gurnett CA, Alaee F, Kruse LM, Desruisseau DM, Hecht JT, Wise CA, Bowcock AM, Dobbs MB. Asymmetric lower-limb malformations in individuals with homeobox PITX1 gene mutation. Am J Hum Genet. 2008;83:616–622.PubMedCrossRef
29.
Zurück zum Zitat Gurnett CA, Alaee, F, Desruisseau, D, Boehm, S, Dobbs, MB. Skeletal muscle contractile gene (TNNT3, MYH3, TPM2) mutations not found in vertical talus or clubfoot. Clin Orthop Relat Res. 2009 Jan 14 [Epub ahead of print]. Gurnett CA, Alaee, F, Desruisseau, D, Boehm, S, Dobbs, MB. Skeletal muscle contractile gene (TNNT3, MYH3, TPM2) mutations not found in vertical talus or clubfoot. Clin Orthop Relat Res. 2009 Jan 14 [Epub ahead of print].
30.
Zurück zum Zitat Gurnett CA, Boehm S, Connolly A, Reimschisel T, Dobbs MB. Impact of congenital talipes equinovarus etiology on treatment outcomes. Dev Med Child Neurol. 2008;50:498–502.PubMedCrossRef Gurnett CA, Boehm S, Connolly A, Reimschisel T, Dobbs MB. Impact of congenital talipes equinovarus etiology on treatment outcomes. Dev Med Child Neurol. 2008;50:498–502.PubMedCrossRef
31.
Zurück zum Zitat Hecht JT, Ester A, Scott A, Wise CA, Iovannisci DM, Lammer EJ, Langlois PH, Blanton SH. NAT2 variation and idiopathic talipes equinovarus (clubfoot). Am J Med Genet A. 2007;143:2285–2291. Hecht JT, Ester A, Scott A, Wise CA, Iovannisci DM, Lammer EJ, Langlois PH, Blanton SH. NAT2 variation and idiopathic talipes equinovarus (clubfoot). Am J Med Genet A. 2007;143:2285–2291.
32.
Zurück zum Zitat Heck AL, Bray MS, Scott A, Blanton SH, Hecht JT. Variation in CASP10 gene is associated with idiopathic talipes equinovarus. J Pediatr Orthop. 2005;25:598–602.PubMedCrossRef Heck AL, Bray MS, Scott A, Blanton SH, Hecht JT. Variation in CASP10 gene is associated with idiopathic talipes equinovarus. J Pediatr Orthop. 2005;25:598–602.PubMedCrossRef
33.
Zurück zum Zitat Honein MA, Paulozzi LJ, Moore CA. Family history, maternal smoking, and clubfoot: an indication of a gene-environment interaction. Am J Epidemiol. 2000;152:658–665.PubMedCrossRef Honein MA, Paulozzi LJ, Moore CA. Family history, maternal smoking, and clubfoot: an indication of a gene-environment interaction. Am J Epidemiol. 2000;152:658–665.PubMedCrossRef
34.
Zurück zum Zitat Hootnick DR, Levinsohn EM, Crider RJ, Packard DS, Jr. Congenital arterial malformations associated with clubfoot. A report of two cases. Clin Orthop Relat Res. 1982;167:160–163.PubMed Hootnick DR, Levinsohn EM, Crider RJ, Packard DS, Jr. Congenital arterial malformations associated with clubfoot. A report of two cases. Clin Orthop Relat Res. 1982;167:160–163.PubMed
35.
Zurück zum Zitat Hudson I, Catterall A. Posterolateral release for resistant club foot. J Bone Joint Surg Br. 1994;76:281–284.PubMed Hudson I, Catterall A. Posterolateral release for resistant club foot. J Bone Joint Surg Br. 1994;76:281–284.PubMed
36.
Zurück zum Zitat Hutchins PM, Foster BK, Paterson DC, Cole EA. Long-term results of early surgical release in club feet. J Bone Joint Surg Br. 1985;67:791–799.PubMed Hutchins PM, Foster BK, Paterson DC, Cole EA. Long-term results of early surgical release in club feet. J Bone Joint Surg Br. 1985;67:791–799.PubMed
37.
Zurück zum Zitat Ippolito E, Farsetti P, Caterini R, Tudisco C. Long-term comparative results in patients with congenital clubfoot treated with two different protocols. J Bone Joint Surg Am. 2003;85:1286–1294.PubMed Ippolito E, Farsetti P, Caterini R, Tudisco C. Long-term comparative results in patients with congenital clubfoot treated with two different protocols. J Bone Joint Surg Am. 2003;85:1286–1294.PubMed
38.
Zurück zum Zitat Jones R. Discussion on the treatment of intractable talipes equinovarus. Trans Brit Orthop Soc. 1895;1:20. Jones R. Discussion on the treatment of intractable talipes equinovarus. Trans Brit Orthop Soc. 1895;1:20.
39.
Zurück zum Zitat Karakurt L, Yilmaz E, Serin E, Bektas B, Cikim G, Gursu F. Plasma total homocysteine level in mothers of children with clubfoot. J Pediatr Orthop. 2003;23:658–660.PubMed Karakurt L, Yilmaz E, Serin E, Bektas B, Cikim G, Gursu F. Plasma total homocysteine level in mothers of children with clubfoot. J Pediatr Orthop. 2003;23:658–660.PubMed
40.
Zurück zum Zitat Kite JH. Some suggestions on the treatment of club foot by casts. J Bone Joint Surg Am. 1963;45:406–412.PubMed Kite JH. Some suggestions on the treatment of club foot by casts. J Bone Joint Surg Am. 1963;45:406–412.PubMed
41.
Zurück zum Zitat Kite JH. Principles involved in the treatment of congenital club-foot. 1939. J Bone Joint Surg Am. 2003;85:1847; discussion 1847.PubMed Kite JH. Principles involved in the treatment of congenital club-foot. 1939. J Bone Joint Surg Am. 2003;85:1847; discussion 1847.PubMed
42.
Zurück zum Zitat Kruse LM, Dobbs MB, Gurnett CA. Polygenic threshold model with sex dimorphism in clubfoot inheritance: the Carter effect. J Bone Joint Surg Am. 2008;90:2688–2694.PubMedCrossRef Kruse LM, Dobbs MB, Gurnett CA. Polygenic threshold model with sex dimorphism in clubfoot inheritance: the Carter effect. J Bone Joint Surg Am. 2008;90:2688–2694.PubMedCrossRef
43.
Zurück zum Zitat Laaveg SJ, Ponseti IV. Long-term results of treatment of congenital club foot. J Bone Joint Surg Am. 1980;62:23–31.PubMed Laaveg SJ, Ponseti IV. Long-term results of treatment of congenital club foot. J Bone Joint Surg Am. 1980;62:23–31.PubMed
44.
Zurück zum Zitat Lochmiller C, Johnston D, Scott A, Risman M, Hecht JT. Genetic epidemiology study of idiopathic talipes equinovarus. Am J Med Genet. 1998;79:90–96.PubMedCrossRef Lochmiller C, Johnston D, Scott A, Risman M, Hecht JT. Genetic epidemiology study of idiopathic talipes equinovarus. Am J Med Genet. 1998;79:90–96.PubMedCrossRef
45.
Zurück zum Zitat Lourenco AF, Morcuende JA. Correction of neglected idiopathic club foot by the Ponseti method. J Bone Joint Surg Br. 2007;89:378–381.PubMedCrossRef Lourenco AF, Morcuende JA. Correction of neglected idiopathic club foot by the Ponseti method. J Bone Joint Surg Br. 2007;89:378–381.PubMedCrossRef
46.
Zurück zum Zitat Lovell WW, Farley D. Treatment of congenital clubfoot. Ona J. 1979;6:453–456.PubMed Lovell WW, Farley D. Treatment of congenital clubfoot. Ona J. 1979;6:453–456.PubMed
47.
Zurück zum Zitat McKay DW. New concept of and approach to clubfoot treatment: section I-principles and morbid anatomy. J Pediatr Orthop. 1982;2:347–356.PubMed McKay DW. New concept of and approach to clubfoot treatment: section I-principles and morbid anatomy. J Pediatr Orthop. 1982;2:347–356.PubMed
48.
Zurück zum Zitat Morcuende JA, Abbasi D, Dolan LA, Ponseti IV. Results of an accelerated Ponseti protocol for clubfoot. J Pediatr Orthop. 2005;25:623–626.PubMedCrossRef Morcuende JA, Abbasi D, Dolan LA, Ponseti IV. Results of an accelerated Ponseti protocol for clubfoot. J Pediatr Orthop. 2005;25:623–626.PubMedCrossRef
49.
Zurück zum Zitat Morcuende JA, Dolan LA, Dietz FR, Ponseti IV. Radical reduction in the rate of extensive corrective surgery for clubfoot using the Ponseti method. Pediatrics. 2004;113:376–380.PubMedCrossRef Morcuende JA, Dolan LA, Dietz FR, Ponseti IV. Radical reduction in the rate of extensive corrective surgery for clubfoot using the Ponseti method. Pediatrics. 2004;113:376–380.PubMedCrossRef
50.
Zurück zum Zitat Phelps AM. The present status of the open incision method for talipes equinovarus. New Engl. Med. Mon. 1891;10:217. Phelps AM. The present status of the open incision method for talipes equinovarus. New Engl. Med. Mon. 1891;10:217.
51.
Zurück zum Zitat Philip J, Silver RK, Wilson RD, Thom EA, Zachary JM, Mohide P, Mahoney MJ, Simpson JL, Platt LD, Pergament E, Hershey D, Filkins K, Johnson A, Shulman LP, Bang J, MacGregor S, Smith JR, Shaw D, Wapner RJ, Jackson LG. Late first-trimester invasive prenatal diagnosis: results of an international randomized trial. Obstet Gynecol. 2004;103:1164–1173.PubMed Philip J, Silver RK, Wilson RD, Thom EA, Zachary JM, Mohide P, Mahoney MJ, Simpson JL, Platt LD, Pergament E, Hershey D, Filkins K, Johnson A, Shulman LP, Bang J, MacGregor S, Smith JR, Shaw D, Wapner RJ, Jackson LG. Late first-trimester invasive prenatal diagnosis: results of an international randomized trial. Obstet Gynecol. 2004;103:1164–1173.PubMed
52.
Zurück zum Zitat Pirani S. A reliable and valid method of assessing the amount of deformity in the congenital clubfoot. St Louis, MO: Pediatric Orthopaedic Society of North America; 2004. Pirani S. A reliable and valid method of assessing the amount of deformity in the congenital clubfoot. St Louis, MO: Pediatric Orthopaedic Society of North America; 2004.
53.
Zurück zum Zitat Pittner DE, Klingele KE, Beebe AC. Treatment of clubfoot with the Ponseti method: a comparison of casting materials. J Pediatr Orthop. 2008;28:250–253.PubMed Pittner DE, Klingele KE, Beebe AC. Treatment of clubfoot with the Ponseti method: a comparison of casting materials. J Pediatr Orthop. 2008;28:250–253.PubMed
54.
Zurück zum Zitat Ponseti IV. Treatment of congenital club foot. J Bone Joint Surg Am. 1992;74:448–454.PubMed Ponseti IV. Treatment of congenital club foot. J Bone Joint Surg Am. 1992;74:448–454.PubMed
55.
Zurück zum Zitat Ponseti IV, Zhivkov M, Davis N, Sinclair M, Dobbs MB, Morcuende JA. Treatment of the complex idiopathic clubfoot. Clin Orthop Relat Res. 2006;451:171–176.PubMedCrossRef Ponseti IV, Zhivkov M, Davis N, Sinclair M, Dobbs MB, Morcuende JA. Treatment of the complex idiopathic clubfoot. Clin Orthop Relat Res. 2006;451:171–176.PubMedCrossRef
56.
Zurück zum Zitat Rebbeck TR, Dietz FR, Murray JC, Buetow KH. A single-gene explanation for the probability of having idiopathic talipes equinovarus. Am J Hum Genet. 1993;53:1051–1063.PubMed Rebbeck TR, Dietz FR, Murray JC, Buetow KH. A single-gene explanation for the probability of having idiopathic talipes equinovarus. Am J Hum Genet. 1993;53:1051–1063.PubMed
57.
Zurück zum Zitat Richards BS, Faulks S, Rathjen KE, Karol LA, Johnston CE, Jones SA. A comparison of two nonoperative methods of idiopathic clubfoot correction: the Ponseti method and the French functional (physiotherapy) method. J Bone Joint Surg Am. 2008;90:2313–2321.PubMedCrossRef Richards BS, Faulks S, Rathjen KE, Karol LA, Johnston CE, Jones SA. A comparison of two nonoperative methods of idiopathic clubfoot correction: the Ponseti method and the French functional (physiotherapy) method. J Bone Joint Surg Am. 2008;90:2313–2321.PubMedCrossRef
58.
Zurück zum Zitat Shapiro MD, Marks ME, Peichel CL, Blackman BK, Nereng KS, Jonsson B, Schluter D, Kingsley DM. Genetic and developmental basis of evolutionary pelvic reduction in threespine sticklebacks. Nature. 2004;428:717–723.PubMedCrossRef Shapiro MD, Marks ME, Peichel CL, Blackman BK, Nereng KS, Jonsson B, Schluter D, Kingsley DM. Genetic and developmental basis of evolutionary pelvic reduction in threespine sticklebacks. Nature. 2004;428:717–723.PubMedCrossRef
59.
Zurück zum Zitat Sharp L, Miedzybrodzka Z, Cardy AH, Inglis J, Madrigal L, Barker S, Chesney D, Clark C, Maffulli N. The C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR), maternal use of folic acid supplements, and risk of isolated clubfoot: a case-parent-triad analysis. Am J Epidemiol. 2006;164:852–861.PubMedCrossRef Sharp L, Miedzybrodzka Z, Cardy AH, Inglis J, Madrigal L, Barker S, Chesney D, Clark C, Maffulli N. The C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR), maternal use of folic acid supplements, and risk of isolated clubfoot: a case-parent-triad analysis. Am J Epidemiol. 2006;164:852–861.PubMedCrossRef
60.
Zurück zum Zitat Simons GW. Complete subtalar release in club feet. Part II–Comparison with less extensive procedures. J Bone Joint Surg Am. 1985;67(7):1056–1065.PubMed Simons GW. Complete subtalar release in club feet. Part II–Comparison with less extensive procedures. J Bone Joint Surg Am. 1985;67(7):1056–1065.PubMed
61.
Zurück zum Zitat Spiegel DA, Shrestha OP, Sitoula P, Rajbhandary T, Bijukachhe B, Banskota AK. Ponseti method for untreated idiopathic clubfeet in Nepalese patients from 1 to 6 years of age. Clin Orthop Relat Res. 2008 Nov 6 [Epub ahead of print]. Spiegel DA, Shrestha OP, Sitoula P, Rajbhandary T, Bijukachhe B, Banskota AK. Ponseti method for untreated idiopathic clubfeet in Nepalese patients from 1 to 6 years of age. Clin Orthop Relat Res. 2008 Nov 6 [Epub ahead of print].
62.
Zurück zum Zitat Sung SS, Brassington AM, Grannatt K, Rutherford A, Whitby FG, Krakowiak PA, Jorde LB, Carey JC, Bamshad M. Mutations in genes encoding fast-twitch contractile proteins cause distal arthrogryposis syndromes. Am J Hum Genet. 2003;72:681–690.PubMedCrossRef Sung SS, Brassington AM, Grannatt K, Rutherford A, Whitby FG, Krakowiak PA, Jorde LB, Carey JC, Bamshad M. Mutations in genes encoding fast-twitch contractile proteins cause distal arthrogryposis syndromes. Am J Hum Genet. 2003;72:681–690.PubMedCrossRef
63.
Zurück zum Zitat Sung SS, Brassington AM, Krakowiak PA, Carey JC, Jorde LB, Bamshad M. Mutations in TNNT3 cause multiple congenital contractures: a second locus for distal arthrogryposis type 2B. Am J Hum Genet. 2003;73:212–214.PubMedCrossRef Sung SS, Brassington AM, Krakowiak PA, Carey JC, Jorde LB, Bamshad M. Mutations in TNNT3 cause multiple congenital contractures: a second locus for distal arthrogryposis type 2B. Am J Hum Genet. 2003;73:212–214.PubMedCrossRef
64.
Zurück zum Zitat Tindall AJ, Steinlechner CW, Lavy CB, Mannion S, Mkandawire N. Results of manipulation of idiopathic clubfoot deformity in Malawi by orthopaedic clinical officers using the Ponseti method: a realistic alternative for the developing world? J Pediatr Orthop. 2005;25:627–629.PubMedCrossRef Tindall AJ, Steinlechner CW, Lavy CB, Mannion S, Mkandawire N. Results of manipulation of idiopathic clubfoot deformity in Malawi by orthopaedic clinical officers using the Ponseti method: a realistic alternative for the developing world? J Pediatr Orthop. 2005;25:627–629.PubMedCrossRef
65.
Zurück zum Zitat Toydemir RM, Rutherford A, Whitby FG, Jorde LB, Carey JC, Bamshad MJ. Mutations in embryonic myosin heavy chain (MYH3) cause Freeman-Sheldon syndrome and Sheldon-Hall syndrome. Nat Genet. 2006;38:561–565.PubMedCrossRef Toydemir RM, Rutherford A, Whitby FG, Jorde LB, Carey JC, Bamshad MJ. Mutations in embryonic myosin heavy chain (MYH3) cause Freeman-Sheldon syndrome and Sheldon-Hall syndrome. Nat Genet. 2006;38:561–565.PubMedCrossRef
66.
Zurück zum Zitat Tredwell SJ, Wilson D, Wilmink MA. Review of the effect of early amniocentesis on foot deformity in the neonate. J Pediatr Orthop. 2001;21:636–641.PubMedCrossRef Tredwell SJ, Wilson D, Wilmink MA. Review of the effect of early amniocentesis on foot deformity in the neonate. J Pediatr Orthop. 2001;21:636–641.PubMedCrossRef
67.
Zurück zum Zitat Turco VJ. Surgical correction of the resistant club foot. One-stage posteromedial release with internal fixation: a preliminary report. J Bone Joint Surg Am. 1971;53:477–497.PubMed Turco VJ. Surgical correction of the resistant club foot. One-stage posteromedial release with internal fixation: a preliminary report. J Bone Joint Surg Am. 1971;53:477–497.PubMed
68.
Zurück zum Zitat Turco VJ. Resistant congenital club foot-one-stage posteromedial release with internal fixation. A follow-up report of a fifteen-year experience. J Bone Joint Surg Am. 1979;61:805–814.PubMed Turco VJ. Resistant congenital club foot-one-stage posteromedial release with internal fixation. A follow-up report of a fifteen-year experience. J Bone Joint Surg Am. 1979;61:805–814.PubMed
69.
Zurück zum Zitat Van Campenhout A, Molenaers G, Moens P, Fabry G. Does functional treatment of idiopathic clubfoot reduce the indication for surgery? Call for a widely accepted rating system. J Pediatr Orthop B. 2001;10:315–318.PubMedCrossRef Van Campenhout A, Molenaers G, Moens P, Fabry G. Does functional treatment of idiopathic clubfoot reduce the indication for surgery? Call for a widely accepted rating system. J Pediatr Orthop B. 2001;10:315–318.PubMedCrossRef
70.
Zurück zum Zitat Veugelers M, Bressan M, McDermott DA, Weremowicz S, Morton CC, Mabry CC, Lefaivre JF, Zunamon A, Destree A, Chaudron JM, Basson CT. Mutation of perinatal myosin heavy chain associated with a Carney complex variant. N Engl J Med. 2004;351:460–469.PubMedCrossRef Veugelers M, Bressan M, McDermott DA, Weremowicz S, Morton CC, Mabry CC, Lefaivre JF, Zunamon A, Destree A, Chaudron JM, Basson CT. Mutation of perinatal myosin heavy chain associated with a Carney complex variant. N Engl J Med. 2004;351:460–469.PubMedCrossRef
71.
Zurück zum Zitat Wang JH, Palmer RM, Chung CS. The role of major gene in clubfoot. Am J Hum Genet. 1988;42:772–776.PubMed Wang JH, Palmer RM, Chung CS. The role of major gene in clubfoot. Am J Hum Genet. 1988;42:772–776.PubMed
72.
Zurück zum Zitat Wang LL, Fu WN, Li-Ling J, Li ZG, Li LY, Sun KL. HOXD13 may play a role in idiopathic congenital clubfoot by regulating the expression of FHL1. Cytogenet Genome Res. 2008;121:189–195.PubMedCrossRef Wang LL, Fu WN, Li-Ling J, Li ZG, Li LY, Sun KL. HOXD13 may play a role in idiopathic congenital clubfoot by regulating the expression of FHL1. Cytogenet Genome Res. 2008;121:189–195.PubMedCrossRef
73.
Zurück zum Zitat Weseley MS, Barenfeld PA, Barrett N. Complications of the treatment of clubfoot. Clin Orthop Relat Res. 1972;84:93–96.PubMedCrossRef Weseley MS, Barenfeld PA, Barrett N. Complications of the treatment of clubfoot. Clin Orthop Relat Res. 1972;84:93–96.PubMedCrossRef
74.
Zurück zum Zitat Wynne-Davies R. Family studies and the cause of congenital club foot, talipes equinovarus, talipes calcaneo-valgus and metatarsus varus. J Bone Joint Surg Br. 1964;46:445–463.PubMed Wynne-Davies R. Family studies and the cause of congenital club foot, talipes equinovarus, talipes calcaneo-valgus and metatarsus varus. J Bone Joint Surg Br. 1964;46:445–463.PubMed
75.
Zurück zum Zitat Wynne-Davies R. Genetic and environmental factors in the etiology of talipes equinovarus. Clin Orthop Relat Res. 1972;84:9–13.PubMedCrossRef Wynne-Davies R. Genetic and environmental factors in the etiology of talipes equinovarus. Clin Orthop Relat Res. 1972;84:9–13.PubMedCrossRef
Metadaten
Titel
Update on Clubfoot: Etiology and Treatment
verfasst von
Matthew B. Dobbs, MD
Christina A. Gurnett, MD, PhD
Publikationsdatum
01.05.2009
Verlag
Springer-Verlag
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 5/2009
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-009-0734-9

Weitere Artikel der Ausgabe 5/2009

Clinical Orthopaedics and Related Research® 5/2009 Zur Ausgabe

Symposium: Clubfoot: Etiology and Treatment

Correcting Residual Deformity Following Clubfoot Releases

Symposium: Clubfoot: Etiology and Treatment

Clubfoot: Etiology and Treatment: Editorial Comment

Symposium: Clubfoot: Etiology and Treatment

Tibialis Anterior Tendon Transfer after Clubfoot Surgery

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.