Skip to main content
Erschienen in: Clinical Orthopaedics and Related Research® 4/2011

01.04.2011 | Symposium: Controversies in Orthopaedics

Is the Etiology of Pretibial Cyst Formation After Absorbable Interference Screw Use Related to a Foreign Body Reaction?

verfasst von: Guillem Gonzalez-Lomas, MD, Ryan T. Cassilly, BS, Fabrizio Remotti, MD, William N. Levine, MD

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 4/2011

Einloggen, um Zugang zu erhalten

Abstract

Background

Arthroscopically assisted anterior cruciate ligament reconstruction using a bioabsorbable tibial fixation screw is occasionally complicated by pretibial cyst formation. The few case reports describing pretibial cyst formation noted several graft types and fixation techniques, making it difficult to establish one etiology. Some literature suggests cysts form from communication between the joint and pretibial area leading to extravasation of joint fluid, maturing into a cyst. We propose the development of cysts after PLLA screw use may be related to a foreign body reaction.

Questions/purposes

We propose this foreign body reaction (1) relates to the biochemical breakdown of bioabsorbable materials; and (2) differs from cystic formations resulting from joint communication.

Methods

We retrospectively reviewed seven patients who developed pretibial cysts at least 2 years after original primary ACL reconstruction surgery. MRI was used to visualize the extent of cystic formation. Cysts were treated by débridement with specimens sent for histologic analysis. Cyst appearance had a 3-year incidence of 5%.

Results

No cyst had an infectious etiology. In all cases, the tibial screw outline was present on MRI, although intraoperatively, the screw was substantially decomposed. Grafts were well incorporated and none of the knees demonstrated anterior laxity. Histologically, cyst material contained fragments of PLLA surrounded by foamy histiocytes, suggesting a foreign body reaction. No cysts recurred.

Conclusions

Tibial cysts occur in a subset of patients undergoing ACL reconstruction using a bioabsorbable PLLA interference screw. We suspect they arise from a foreign body response to the screw breakdown. Removal is well tolerated.

Level of Evidence

Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
Literatur
1.
Zurück zum Zitat Benedetto KP, Fellinger M, Lim TE, Passler JM, Schoen JL, Willems WJ. A new bioabsorbable interference screw: preliminary results of a prospective, multicenter, randomized clinical trial. Arthroscopy. 2000;16:41−48.PubMedCrossRef Benedetto KP, Fellinger M, Lim TE, Passler JM, Schoen JL, Willems WJ. A new bioabsorbable interference screw: preliminary results of a prospective, multicenter, randomized clinical trial. Arthroscopy. 2000;16:41−48.PubMedCrossRef
2.
Zurück zum Zitat Bostman OM. Intense granulomatous inflammatory lesions associated with absorbable internal fixation devices made of polyglycolide in ankle fractures. Clin Orthop Relat Res. 1992;278:193−199.PubMed Bostman OM. Intense granulomatous inflammatory lesions associated with absorbable internal fixation devices made of polyglycolide in ankle fractures. Clin Orthop Relat Res. 1992;278:193−199.PubMed
3.
Zurück zum Zitat Bostman OM, Pihlajamaki HK. Adverse tissue reactions to bioabsorbable fixation devices. Clin Orthop Relat Res. 2000;371:216−227.PubMedCrossRef Bostman OM, Pihlajamaki HK. Adverse tissue reactions to bioabsorbable fixation devices. Clin Orthop Relat Res. 2000;371:216−227.PubMedCrossRef
4.
Zurück zum Zitat Deie M, Sumen Y, Ochi M, Murakami Y, Fujimoto E, Ikuta Y. Pretibial cyst formation after anterior cruciate ligament reconstruction using auto hamstring grafts: two case reports in a prospective study of 89 cases. Magn Reson Imaging. 2000;18:973−977.PubMedCrossRef Deie M, Sumen Y, Ochi M, Murakami Y, Fujimoto E, Ikuta Y. Pretibial cyst formation after anterior cruciate ligament reconstruction using auto hamstring grafts: two case reports in a prospective study of 89 cases. Magn Reson Imaging. 2000;18:973−977.PubMedCrossRef
5.
Zurück zum Zitat Feldmann DD, Fanelli GC. Development of a synovial cyst following anterior cruciate ligament reconstruction. Arthroscopy. 2001;17:200−202.PubMedCrossRef Feldmann DD, Fanelli GC. Development of a synovial cyst following anterior cruciate ligament reconstruction. Arthroscopy. 2001;17:200−202.PubMedCrossRef
6.
Zurück zum Zitat Ilahi OA, Younas SA, Sahni IK. Pretibial cyst formation after arthroscopic anterior cruciate ligament reconstruction. Arthroscopy. 2003;19:E5.PubMedCrossRef Ilahi OA, Younas SA, Sahni IK. Pretibial cyst formation after arthroscopic anterior cruciate ligament reconstruction. Arthroscopy. 2003;19:E5.PubMedCrossRef
7.
Zurück zum Zitat Lind M, Feller J, Webster KE. Tibial bone tunnel widening is reduced by polylactate/hydroxyapatite interference screws compared to metal screws after ACL reconstruction with hamstring grafts. Knee. 2009;16:447−451.PubMedCrossRef Lind M, Feller J, Webster KE. Tibial bone tunnel widening is reduced by polylactate/hydroxyapatite interference screws compared to metal screws after ACL reconstruction with hamstring grafts. Knee. 2009;16:447−451.PubMedCrossRef
8.
Zurück zum Zitat Malhan K, Kumar A, Rees D. Tibial cyst formation after anterior cruciate ligament reconstruction using a new bioabsorbable screw. Knee. 2002;9:73−75.PubMedCrossRef Malhan K, Kumar A, Rees D. Tibial cyst formation after anterior cruciate ligament reconstruction using a new bioabsorbable screw. Knee. 2002;9:73−75.PubMedCrossRef
9.
Zurück zum Zitat Martinek V, Friederich NF. Tibial and pretibial cyst formation after anterior cruciate ligament reconstruction with bioabsorbable interference screw fixation. Arthroscopy. 1999;15:317−320.PubMedCrossRef Martinek V, Friederich NF. Tibial and pretibial cyst formation after anterior cruciate ligament reconstruction with bioabsorbable interference screw fixation. Arthroscopy. 1999;15:317−320.PubMedCrossRef
10.
Zurück zum Zitat McGuire DA, Barber FA, Elrod BF, Paulos LE. Bioabsorbable interference screws for graft fixation in anterior cruciate ligament reconstruction. Arthroscopy. 1999;15:463−473.PubMedCrossRef McGuire DA, Barber FA, Elrod BF, Paulos LE. Bioabsorbable interference screws for graft fixation in anterior cruciate ligament reconstruction. Arthroscopy. 1999;15:463−473.PubMedCrossRef
11.
Zurück zum Zitat Pihlajamaki H, Bostman O, Tynninen O, Laitinen O. Long-term tissue response to bioabsorbable poly-l-lactide and metallic screws: an experimental study. Bone. 2006;39:932−937.PubMedCrossRef Pihlajamaki H, Bostman O, Tynninen O, Laitinen O. Long-term tissue response to bioabsorbable poly-l-lactide and metallic screws: an experimental study. Bone. 2006;39:932−937.PubMedCrossRef
12.
Zurück zum Zitat Radford MJ, Noakes J, Read J, Wood DG. The natural history of a bioabsorbable interference screw used for anterior cruciate ligament reconstruction with a 4-strand hamstring technique. Arthroscopy. 2005;21:707−710.PubMedCrossRef Radford MJ, Noakes J, Read J, Wood DG. The natural history of a bioabsorbable interference screw used for anterior cruciate ligament reconstruction with a 4-strand hamstring technique. Arthroscopy. 2005;21:707−710.PubMedCrossRef
13.
Zurück zum Zitat Sanders TG, Tall MA, Mulloy JP, Leis HT. Fluid collections in the osseous tunnel during the first year after anterior cruciate ligament repair using an autologous hamstring graft: natural history and clinical correlation. J Comput Assist Tomogr. 2002;26:617−621.PubMedCrossRef Sanders TG, Tall MA, Mulloy JP, Leis HT. Fluid collections in the osseous tunnel during the first year after anterior cruciate ligament repair using an autologous hamstring graft: natural history and clinical correlation. J Comput Assist Tomogr. 2002;26:617−621.PubMedCrossRef
14.
Zurück zum Zitat Simonian PT, Wickiewicz TL, O’Brien SJ, Dines JS, Schatz JA, Warren RF. Pretibial cyst formation after anterior cruciate ligament surgery with soft tissue autografts. Arthroscopy. 1998;14:215−220.PubMedCrossRef Simonian PT, Wickiewicz TL, O’Brien SJ, Dines JS, Schatz JA, Warren RF. Pretibial cyst formation after anterior cruciate ligament surgery with soft tissue autografts. Arthroscopy. 1998;14:215−220.PubMedCrossRef
15.
Zurück zum Zitat Tsuda E, Ishibashi Y, Tazawa K, Sato H, Kusumi T, Toh S. Pretibial cyst formation after anterior cruciate ligament reconstruction with a hamstring tendon autograft. Arthroscopy. 2006;22:691.e1−6. Tsuda E, Ishibashi Y, Tazawa K, Sato H, Kusumi T, Toh S. Pretibial cyst formation after anterior cruciate ligament reconstruction with a hamstring tendon autograft. Arthroscopy. 2006;22:691.e1−6.
16.
Zurück zum Zitat Victoroff BN, Paulos L, Beck C, Goodfellow DB. Subcutaneous pretibial cyst formation associated with anterior cruciate ligament allografts: a report of four cases and literature review. Arthroscopy. 1995;11:486−494.PubMedCrossRef Victoroff BN, Paulos L, Beck C, Goodfellow DB. Subcutaneous pretibial cyst formation associated with anterior cruciate ligament allografts: a report of four cases and literature review. Arthroscopy. 1995;11:486−494.PubMedCrossRef
17.
Zurück zum Zitat Weiler A, Hoffmann RF, Stahelin AC, Helling HJ, Sudkamp NP. Biodegradable implants in sports medicine: the biological base. Arthroscopy. 2000;16:305−321.PubMedCrossRef Weiler A, Hoffmann RF, Stahelin AC, Helling HJ, Sudkamp NP. Biodegradable implants in sports medicine: the biological base. Arthroscopy. 2000;16:305−321.PubMedCrossRef
18.
Zurück zum Zitat Williams RJ. Controversies in Knee Surgery. New York, NY: Oxford University Press, Inc; 2004. Williams RJ. Controversies in Knee Surgery. New York, NY: Oxford University Press, Inc; 2004.
Metadaten
Titel
Is the Etiology of Pretibial Cyst Formation After Absorbable Interference Screw Use Related to a Foreign Body Reaction?
verfasst von
Guillem Gonzalez-Lomas, MD
Ryan T. Cassilly, BS
Fabrizio Remotti, MD
William N. Levine, MD
Publikationsdatum
01.04.2011
Verlag
Springer-Verlag
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 4/2011
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-010-1580-5

Weitere Artikel der Ausgabe 4/2011

Clinical Orthopaedics and Related Research® 4/2011 Zur Ausgabe

Symposium: Periprosthetic Joint Infection

Periprosthetic Joint Infection: Editorial Comment

Symposium: Periprosthetic Joint Infection

Biographical Sketch: William S. Baer (1872–1931)

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.