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Erschienen in: Clinical Orthopaedics and Related Research® 9/2012

01.09.2012 | Symposium: Legg-Calvé-Perthes Disease: Where Do We Stand After 100 Years?

Do Femoral or Salter Innominate Osteotomies Improve Femoral Head Sphericity in Legg-Calvé-Perthes Disease? A Meta-analysis

verfasst von: Neil Saran, MD, MHSc, FRCSC, Renjit Varghese, MBBS, MS (Orth), MHSc, Kishore Mulpuri, MBBS, MS (Orth), MHSc

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 9/2012

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Abstract

Background

Recently, the authors of two prospective multicenter observational studies recommended surgery to improve head sphericity in older children, whereas large retrospective observational studies suggest that surgery does not improve head sphericity in older children. Thus, the treatment for Legg-Calvé-Perthes disease (LCPD) remains controversial.

Questions/purposes

Using a meta-analysis we asked whether femoral varus osteotomy (FVO) or Salter innominate osteotomy (SIO) resulted in better radiographic head sphericity at the end of the disease process as compared with nonsurgical modalities.

Methods

We systematically searched the literature using the key concepts LCPD, operative treatment, and nonoperative treatment. Of 160 abstracts, 57 full-text studies were reviewed and 14 papers chosen for meta-analysis. Subgroup analyses were performed to assess the impact of age and stage of disease. The odds of a spherical head after operative compared with nonoperative treatment were calculated to measure effect size for each study and a pooled odds ratio (OR) calculated.

Results

Head sphericity improved (OR, 1.29; 95% CI, 1.05–1.60) by FVO or SIO as compared with patients treated nonoperatively. In children younger than 6 years, it did not alter femoral head sphericity (OR, 1.02; 95% CI, 0.45–2.36); children 6 years of age and older were more likely to have better femoral head sphericity from surgical treatment than nonoperative treatment (OR, 2.05; 95% CI, 1.28–3.26).

Conclusions

The data suggest FVO or SIO in patients with LCPD disease who are older than 6 years of age during or before the fragmentation phase should be considered.

Level of Evidence

Level III, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
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Metadaten
Titel
Do Femoral or Salter Innominate Osteotomies Improve Femoral Head Sphericity in Legg-Calvé-Perthes Disease? A Meta-analysis
verfasst von
Neil Saran, MD, MHSc, FRCSC
Renjit Varghese, MBBS, MS (Orth), MHSc
Kishore Mulpuri, MBBS, MS (Orth), MHSc
Publikationsdatum
01.09.2012
Verlag
Springer-Verlag
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 9/2012
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-012-2326-3

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