Skip to main content
Erschienen in: Clinical Orthopaedics and Related Research® 12/2012

01.12.2012 | Clinical Research

Reliability of Lower-limb Alignment Measurements in Patients With Multiple Epiphyseal Dysplasia

verfasst von: Bekhzad Akhmedov, MD, Ki Hyuk Sung, MD, Chin Youb Chung, MD, Kyoung Min Lee, MD, Moon Seok Park, MD

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 12/2012

Einloggen, um Zugang zu erhalten

Abstract

Background

Although radiographic measurements are used in multiple epiphyseal dysplasia (MED) during correction of lower-limb alignment, the reliabilities of the measurements are unclear.

Questions/Purposes

We determined interobserver and intraobserver reliabilities of the measurement methods used in evaluation of lower-limb alignment in MED.

Methods

After consensus building, we included 10 radiographic measurement methods widely used to evaluate lower-limb alignment: mechanical tibiofemoral angle, anatomic tibiofemoral angle, mechanical axis deviation, joint line convergence angle, mechanical lateral distal femoral angle, anatomic lateral distal femoral angle, mechanical medial proximal tibial angle, anatomic medial proximal tibial angle, epimetaphyseal angle, and tibial metadiaphyseal angle. A study group consisting of 30 patients with MED was compared with a control group consisting of 30 sex- and age-matched patients with genu varum and genu valgum. Mean age in both groups was 11 years (study group: SD, 2 years; range, 6–16 years; control group: SD, 2 years; range, 6–15 years). Interobserver and intraobserver reliabilities of all radiographic measurement methods were obtained and expressed by intraclass correlation coefficients (ICCs).

Results

Mechanical tibiofemoral angle, anatomic tibiofemoral angle, and mechanical axis deviation were associated with high interobserver reliability (ICCs, 0.987, 0.985 and 0.982, respectively). Epimetaphyseal angle had the lowest reliability (ICC, 0.280). Intraobserver reliability exhibited similar trends, with mechanical axis deviation and mechanical tibiofemoral angle having the highest ICCs and epimetaphyseal angle the lowest.

Conclusions

Mechanical tibiofemoral angle, anatomic tibiofemoral angle, and mechanical axis deviation are reasonably reliable measures of alignment in MED. The lateral distal femoral angle and medial proximal tibial angle (mechanical and anatomic) can be used as complementary measurement methods.

Level of Evidence

Level II, diagnostic study. See Instructions for Authors for a complete description of levels of evidence.
Literatur
1.
Zurück zum Zitat Andersen PE Jr, Hauge M. Congenital generalised bone dysplasias: a clinical, radiological, and epidemiological survey. J Med Genet. 1989;26:37–44.PubMedCrossRef Andersen PE Jr, Hauge M. Congenital generalised bone dysplasias: a clinical, radiological, and epidemiological survey. J Med Genet. 1989;26:37–44.PubMedCrossRef
2.
Zurück zum Zitat Bonett DG. Sample size requirements for estimating intraclass correlations with desired precision. Stat Med. 2002;21:1331–1335.PubMedCrossRef Bonett DG. Sample size requirements for estimating intraclass correlations with desired precision. Stat Med. 2002;21:1331–1335.PubMedCrossRef
3.
Zurück zum Zitat Cho TJ, Choi IH, Chung CY, Yoo WJ, Park MS, Lee DY. Hemiepiphyseal stapling for angular deformity correction around the knee joint in children with multiple epiphyseal dysplasia. J Pediatr Orthop. 2009;29:52–56.PubMedCrossRef Cho TJ, Choi IH, Chung CY, Yoo WJ, Park MS, Lee DY. Hemiepiphyseal stapling for angular deformity correction around the knee joint in children with multiple epiphyseal dysplasia. J Pediatr Orthop. 2009;29:52–56.PubMedCrossRef
4.
Zurück zum Zitat Davids JR, Blackhurst DW, Allen BL Jr. Radiographic evaluation of bowed legs in children. J Pediatr Orthop. 2001;21:257–263.PubMedCrossRef Davids JR, Blackhurst DW, Allen BL Jr. Radiographic evaluation of bowed legs in children. J Pediatr Orthop. 2001;21:257–263.PubMedCrossRef
5.
Zurück zum Zitat Feldman DS, Henderson ER, Levine HB, Schrank PL, Koval KJ, Patel RJ, Spencer DB, Sala DA, Egol KA. Interobserver and intraobserver reliability in lower-limb deformity correction measurements. J Pediatr Orthop. 2007;27:204–208.PubMedCrossRef Feldman DS, Henderson ER, Levine HB, Schrank PL, Koval KJ, Patel RJ, Spencer DB, Sala DA, Egol KA. Interobserver and intraobserver reliability in lower-limb deformity correction measurements. J Pediatr Orthop. 2007;27:204–208.PubMedCrossRef
6.
Zurück zum Zitat Fleiss JL, Levin B, Paik MC. The measurement of interrater agreement. Statistical Methods for Rates and Proportions. Hoboken, NJ: John Wiley & Sons, Inc; 2004:598–626. Fleiss JL, Levin B, Paik MC. The measurement of interrater agreement. Statistical Methods for Rates and Proportions. Hoboken, NJ: John Wiley & Sons, Inc; 2004:598–626.
7.
Zurück zum Zitat Fraser RK, Dickens DR, Cole WG. Medial physeal stapling for primary and secondary genu valgum in late childhood and adolescence. J Bone Joint Surg Br. 1995;77:733–735.PubMed Fraser RK, Dickens DR, Cole WG. Medial physeal stapling for primary and secondary genu valgum in late childhood and adolescence. J Bone Joint Surg Br. 1995;77:733–735.PubMed
8.
Zurück zum Zitat Gordon JE, Chen RC, Dobbs MB, Luhmann SJ, Rich MM, Schoenecker PL. Interobserver and intraobserver reliability in the evaluation of mechanical axis deviation. J Pediatr Orthop. 2009;29:281–284.PubMedCrossRef Gordon JE, Chen RC, Dobbs MB, Luhmann SJ, Rich MM, Schoenecker PL. Interobserver and intraobserver reliability in the evaluation of mechanical axis deviation. J Pediatr Orthop. 2009;29:281–284.PubMedCrossRef
9.
Zurück zum Zitat Inan M, Jeong C, Chan G, Mackenzie WG, Glutting J. Analysis of lower extremity alignment in achondroplasia: interobserver reliability and intraobserver reproducibility. J Pediatr Orthop. 2006;26:75–78.PubMedCrossRef Inan M, Jeong C, Chan G, Mackenzie WG, Glutting J. Analysis of lower extremity alignment in achondroplasia: interobserver reliability and intraobserver reproducibility. J Pediatr Orthop. 2006;26:75–78.PubMedCrossRef
10.
Zurück zum Zitat Karanicolas PJ, Bhandari M, Kreder H, Moroni A, Richardson M, Walter SD, Norman GR, Guyatt GH; Collaboration for Outcome Assessment in Surgical Trials (COAST) Musculoskeletal Group. Evaluating agreement: conducting a reliability study. J Bone Joint Surg Am. 2009;91(suppl 3):99–106.PubMedCrossRef Karanicolas PJ, Bhandari M, Kreder H, Moroni A, Richardson M, Walter SD, Norman GR, Guyatt GH; Collaboration for Outcome Assessment in Surgical Trials (COAST) Musculoskeletal Group. Evaluating agreement: conducting a reliability study. J Bone Joint Surg Am. 2009;91(suppl 3):99–106.PubMedCrossRef
11.
Zurück zum Zitat Kim OH, Park H, Seong MW, Cho TJ, Nishimura G, Superti-Furga A, Unger S, Ikegawa S, Choi IH, Song HR, Kim HW, Yoo WJ, Shim JS, Chung CY, Oh CW, Jeong C, Song KS, Seo SG, Cho SI, Yeo IK, Kim SY, Park S, Park SS. Revisit of multiple epiphyseal dysplasia: ethnic difference in genotypes and comparison of radiographic features linked to the COMP and MATN3 genes. Am J Med Genet A. 2011;155A:2669–2680.PubMed Kim OH, Park H, Seong MW, Cho TJ, Nishimura G, Superti-Furga A, Unger S, Ikegawa S, Choi IH, Song HR, Kim HW, Yoo WJ, Shim JS, Chung CY, Oh CW, Jeong C, Song KS, Seo SG, Cho SI, Yeo IK, Kim SY, Park S, Park SS. Revisit of multiple epiphyseal dysplasia: ethnic difference in genotypes and comparison of radiographic features linked to the COMP and MATN3 genes. Am J Med Genet A. 2011;155A:2669–2680.PubMed
12.
Zurück zum Zitat Lavelle WF, Shovlin J, Drvaric DM. Reliability of the metaphyseal-diaphyseal angle in tibia vara as measured on digital images by pediatric orthopaedic surgeons. J Pediatr Orthop. 2008;28:695–698.PubMedCrossRef Lavelle WF, Shovlin J, Drvaric DM. Reliability of the metaphyseal-diaphyseal angle in tibia vara as measured on digital images by pediatric orthopaedic surgeons. J Pediatr Orthop. 2008;28:695–698.PubMedCrossRef
13.
Zurück zum Zitat Levine AM, Drennan JC. Physiological bowing and tibia vara: the metaphyseal-diaphyseal angle in the measurement of bowleg deformities. J Bone Joint Surg Am. 1982;64:1158–1163.PubMed Levine AM, Drennan JC. Physiological bowing and tibia vara: the metaphyseal-diaphyseal angle in the measurement of bowleg deformities. J Bone Joint Surg Am. 1982;64:1158–1163.PubMed
14.
Zurück zum Zitat Manner HM, Radler C, Ganger R, Grill F. Knee deformity in congenital longitudinal deficiencies of the lower extremity. Clin Orthop Relat Res. 2006;448:185–192.PubMedCrossRef Manner HM, Radler C, Ganger R, Grill F. Knee deformity in congenital longitudinal deficiencies of the lower extremity. Clin Orthop Relat Res. 2006;448:185–192.PubMedCrossRef
15.
Zurück zum Zitat Marx RG, Grimm P, Lillemoe KA, Robertson CM, Ayeni OR, Lyman S, Bogner EA, Pavlov H. Reliability of lower extremity alignment measurement using radiographs and PACS. Knee Surg Sports Traumatol Arthrosc. 2011;19:1693–1698.PubMedCrossRef Marx RG, Grimm P, Lillemoe KA, Robertson CM, Ayeni OR, Lyman S, Bogner EA, Pavlov H. Reliability of lower extremity alignment measurement using radiographs and PACS. Knee Surg Sports Traumatol Arthrosc. 2011;19:1693–1698.PubMedCrossRef
16.
Zurück zum Zitat Paley D. Principles of Deformity Correction. 2nd ed. Berlin, Germany: Springer-Verlag; 2002:1–18. Paley D. Principles of Deformity Correction. 2nd ed. Berlin, Germany: Springer-Verlag; 2002:1–18.
17.
Zurück zum Zitat Park MS, Kim SJ, Chung CY, Choi IH, Lee SH, Lee KM. Statistical consideration for bilateral cases in orthopaedic research. J Bone Joint Surg Am. 2010;92:1732–1737.PubMedCrossRef Park MS, Kim SJ, Chung CY, Choi IH, Lee SH, Lee KM. Statistical consideration for bilateral cases in orthopaedic research. J Bone Joint Surg Am. 2010;92:1732–1737.PubMedCrossRef
18.
Zurück zum Zitat Raab P, Wild A, Seller K, Krauspe R. Correction of length discrepancies and angular deformities of the leg by Blount’s epiphyseal stapling. Eur J Pediatr. 2001;160:668–674.PubMed Raab P, Wild A, Seller K, Krauspe R. Correction of length discrepancies and angular deformities of the leg by Blount’s epiphyseal stapling. Eur J Pediatr. 2001;160:668–674.PubMed
19.
Zurück zum Zitat Sabharwal S, Green S, McCarthy J, Hamdy RC. What’s new in limb lengthening and deformity correction. J Bone Joint Surg Am. 2011;93:213–221.PubMedCrossRef Sabharwal S, Green S, McCarthy J, Hamdy RC. What’s new in limb lengthening and deformity correction. J Bone Joint Surg Am. 2011;93:213–221.PubMedCrossRef
20.
Zurück zum Zitat Sabharwal S, Zhao C. The hip-knee-ankle angle in children: reference values based on a full-leg standing radiograph. J Bone Joint Surg Am. 2009;91:2461–2468.PubMedCrossRef Sabharwal S, Zhao C. The hip-knee-ankle angle in children: reference values based on a full-leg standing radiograph. J Bone Joint Surg Am. 2009;91:2461–2468.PubMedCrossRef
21.
Zurück zum Zitat Sabharwal S, Zhao C, Edgar M. Lower limb alignment in children: reference values based on a full-leg standing radiograph. J Pediatr Orthop. 2008;28:740–746.PubMedCrossRef Sabharwal S, Zhao C, Edgar M. Lower limb alignment in children: reference values based on a full-leg standing radiograph. J Pediatr Orthop. 2008;28:740–746.PubMedCrossRef
22.
Zurück zum Zitat Segev E, Hemo Y, Wientroub S, Ovadia D, Fishkin M, Steinberg DM, Hayek S. Intra- and interobserver reliability analysis of digital radiographic measurements for pediatric orthopedic parameters using a novel PACS integrated computer software program. J Child Orthop. 2010;4:331–341.PubMedCrossRef Segev E, Hemo Y, Wientroub S, Ovadia D, Fishkin M, Steinberg DM, Hayek S. Intra- and interobserver reliability analysis of digital radiographic measurements for pediatric orthopedic parameters using a novel PACS integrated computer software program. J Child Orthop. 2010;4:331–341.PubMedCrossRef
23.
Zurück zum Zitat Sled EA, Sheehy LM, Felson DT, Costigan PA, Lam M, Cooke TD. Reliability of lower limb alignment measures using an established landmark-based method with a customized computer software program. Rheumatol Int. 2011;31:71–77.PubMedCrossRef Sled EA, Sheehy LM, Felson DT, Costigan PA, Lam M, Cooke TD. Reliability of lower limb alignment measures using an established landmark-based method with a customized computer software program. Rheumatol Int. 2011;31:71–77.PubMedCrossRef
24.
Zurück zum Zitat Specogna AV, Birmingham TB, DaSilva JJ, Milner JS, Kerr J, Hunt MA, Jones IC, Jenkyn TR, Fowler PJ, Giffin JR. Reliability of lower limb frontal plane alignment measurements using plain radiographs and digitized images. J Knee Surg. 2004;17:203–210.PubMed Specogna AV, Birmingham TB, DaSilva JJ, Milner JS, Kerr J, Hunt MA, Jones IC, Jenkyn TR, Fowler PJ, Giffin JR. Reliability of lower limb frontal plane alignment measurements using plain radiographs and digitized images. J Knee Surg. 2004;17:203–210.PubMed
25.
Zurück zum Zitat Spranger JW, Brill PW, Poznanski AK. Bone Dysplasias: An Atlas of Genetic Disorders of Skeletal Development. 2nd ed. New York, NY: Oxford University Press; 2002:141–142. Spranger JW, Brill PW, Poznanski AK. Bone Dysplasias: An Atlas of Genetic Disorders of Skeletal Development. 2nd ed. New York, NY: Oxford University Press; 2002:141–142.
26.
Zurück zum Zitat Stricker SJ, Faustgen JP. Radiographic measurement of bowleg deformity: variability due to method and limb rotation. J Pediatr Orthop. 1994;14:147–151.PubMedCrossRef Stricker SJ, Faustgen JP. Radiographic measurement of bowleg deformity: variability due to method and limb rotation. J Pediatr Orthop. 1994;14:147–151.PubMedCrossRef
27.
Zurück zum Zitat Unger S, Bonafe L, Superti-Furga A. Multiple epiphyseal dysplasia: clinical and radiographic features, differential diagnosis and molecular basis. Best Pract Res Clin Rheumatol. 2008;22:19–32.PubMedCrossRef Unger S, Bonafe L, Superti-Furga A. Multiple epiphyseal dysplasia: clinical and radiographic features, differential diagnosis and molecular basis. Best Pract Res Clin Rheumatol. 2008;22:19–32.PubMedCrossRef
28.
Zurück zum Zitat Zuege RC, Kempken TG, Blount WP. Epiphyseal stapling for angular deformity at the knee. J Bone Joint Surg Am. 1979;61:320–329.PubMed Zuege RC, Kempken TG, Blount WP. Epiphyseal stapling for angular deformity at the knee. J Bone Joint Surg Am. 1979;61:320–329.PubMed
Metadaten
Titel
Reliability of Lower-limb Alignment Measurements in Patients With Multiple Epiphyseal Dysplasia
verfasst von
Bekhzad Akhmedov, MD
Ki Hyuk Sung, MD
Chin Youb Chung, MD
Kyoung Min Lee, MD
Moon Seok Park, MD
Publikationsdatum
01.12.2012
Verlag
Springer-Verlag
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 12/2012
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-012-2548-4

Weitere Artikel der Ausgabe 12/2012

Clinical Orthopaedics and Related Research® 12/2012 Zur Ausgabe

Symposium: ABJS Carl T. Brighton Workshop on Hip Preservation Surgery

Coxa Profunda: Is the Deep Acetabulum Overcovered?

Symposium: ABJS Carl T. Brighton Workshop on Hip Preservation Surgery

ABJS Carl T. Brighton Workshop on Hip Preservation Surgery: Editorial Comment

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.