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01.04.2016 | Research Letter

Elevated 1-hour plasma glucose levels are associated with dysglycemia, impaired beta-cell function, and insulin sensitivity: a pilot study from a real world health care setting

verfasst von: Ram Jagannathan, Mary Ann Sevick, Huilin Li, Dorothy Fink, Rachel Dankner, Angela Chetrit, Jesse Roth, Michael Bergman

Erschienen in: Endocrine | Ausgabe 1/2016

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Individuals with prediabetes, namely impaired glucose tolerance (IGT) and/or impaired fasting glucose (IFG), are at increased risk of developing type 2 diabetes mellitus (T2DM) and cardiovascular disease. However, only 30–40 % of those with IFG/IGT eventually develop T2DM [1‐3]. In fact, about 40 % of individuals who develop T2DM after 10 years have Normal Glucose Tolerance (NGT) at baseline [3], indicating that the conventional fasting and 2-h oral glucose tolerance test (OGTT) do not recognize most high-risk individuals. …

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T.V. Fiorentino, M.A. Marini, F. Andreozzi, F. Arturi, E. Succurro, M. Perticone, A. Sciacqua, M. Letizia Hribal, F. Perticone, G. Sesti, One-hour post-load hyperglycemia is a stronger predictor of type 2 diabetes than impaired fasting glucose. J. Clin. Endocrinol. Metab. (2015). doi:10.1210/jc.2015-2573 PubMed

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Titel: Elevated 1-hour plasma glucose levels are associated with dysglycemia, impaired beta-cell function, and insulin sensitivity: a pilot study from a real world health care setting
verfasst von: Ram Jagannathan
Mary Ann Sevick
Huilin Li
Dorothy Fink
Rachel Dankner
Angela Chetrit
Jesse Roth
Michael Bergman
Publikationsdatum: 01.04.2016
Verlag: Springer US
Erschienen in: Endocrine / Ausgabe 1/2016
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-015-0746-z

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Elevated 1-hour plasma glucose levels are associated with dysglycemia, impaired beta-cell function, and insulin sensitivity: a pilot study from a real world health care setting

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