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Forensic Science, Medicine and Pathology

Erschienen in:

01.03.2011 | Review

Gene variants predisposing to SIDS: current knowledge

verfasst von: Siri H. Opdal, Torleiv O. Rognum

Erschienen in: Forensic Science, Medicine and Pathology | Ausgabe 1/2011

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Abstract

Genetic risk factors play a role in sudden unexpected infant death; either as a cause of death, such as in cases with medium-chain acyl-coenzyme A dehydrogenase deficiency and cardiac arrest due to long QT syndrome, or as predisposing factors for sudden infant death syndrome (SIDS). Most likely genetic predisposition to SIDS represent a polygenic inheritance pattern leading to sudden death when combined with other risk factors, such as a vulnerable developmental stage of the central nervous system and/or the immune system, in addition to environmental risk factors, such as a common cold or prone sleeping position. Genes involved in the regulation of the immune system, cardiac function, the serotonergic network and brain function and development have so far emerged as the most important with respect to SIDS. The purpose of the present paper is to survey current knowledge on SIDS and possible genetic contributions.

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Titel: Gene variants predisposing to SIDS: current knowledge
verfasst von: Siri H. Opdal
Torleiv O. Rognum
Publikationsdatum: 01.03.2011
Verlag: Springer US
Erschienen in: Forensic Science, Medicine and Pathology / Ausgabe 1/2011
Print ISSN: 1547-769X
Elektronische ISSN: 1556-2891
DOI: https://doi.org/10.1007/s12024-010-9182-9

Neu im Fachgebiet Pathologie

01.04.2024 | Forensische Traumatologie | CME

Springer Medizin

Gene variants predisposing to SIDS: current knowledge

Abstract

Neu im Fachgebiet Pathologie

Theoretische Grundlagen von Explosionen und Explosionsverletzungen

Auswirkungen vorgeschalteter Laborprozesse auf die Digitalisierung histologischer Schnittpräparate

Knochenmarkhistologie bei Zytopenien

Herausforderungen der Automation bei der quantitativen Auswertung von Leberbiopsien

Springer Medizin

Abstract

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