Erschienen in:
01.05.2011
On the logic of restrictive recognition of peptide by the T-cell antigen receptor
verfasst von:
Melvin Cohn
Erschienen in:
Immunologic Research
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Ausgabe 1/2011
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Abstract
This essay provides an analysis of the inadequacy of the current view of restrictive recognition of peptide by the T-cell antigen receptor. A competing model is developed, and the experimental evidence for the prevailing model is reinterpreted in the new framework. The goal is to contrast the two models with respect to their consistency, coverage of the data, explanatory power, and predictability.