Skip to main content

Advertisement

Log in

The Use of Enucleation and Chemical Cauterization (Carnoy’s) in the Management of Odontogenic Keratocyst of the Jaws

  • Original Article
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

The purpose of this study was to evaluate the use of enucleation and chemical cauterization in the management of odontogenic keratocyst (OKC) of the jaw. This study involves the retrospective review of 32 patients (20 males and 12 females) with 34 biopsy proven odontogenic keratocysts. All patients received a combination of enucleation and chemical cauterization with every time freshly prepared Carnoy’s solution (absolute alcohol 6 mL, chloroform 3 mL, glacial acetic acid 1 mL, ferric chloride 0.1 gm/mL). None of these patients were diagnosed with basal cell nevus syndrome. Four of these patients did not give the follow up and were not included in the study. A total of 30 biopsy proven OKC were resolved with this treatment method. Post-operative follow up consists of clinical and radiographic examination. Follow up time ranged from a minimum of 2 years to a maximum of 5 years. Mean follow up was of 2.8 years. Recurrence rate of 5.8% was observed. Hence, concluded that the combination of enucleation and chemical cauterization may offer patients improved therapy in the management of odontogenic keratocysts of the jaws.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Philipsen HP (1956) On keratocysts in the jaw. Tandlaegebladet 60:963

    Google Scholar 

  2. Pindborg JJ, Hansen J (1963) Studies on odontogenic cyst epithelium, II: Clinical and roentgenologic aspects of odontogenic keratocysts. Acta Pathol Microbiol Scand 58:283

    Article  CAS  PubMed  Google Scholar 

  3. Thawley SE, Panje WR, Batsakis JG et al (1999) Comprehensive management of head and neck tumors, vol 2, 2nd edn. WB Saunders, Philadelphia, p 1556

    Google Scholar 

  4. Zachariades N, Papanicolaou S, Triantafyllou D (1985) Odontogenic keratocyst: review of the literature and report of sixteen cases. J Oral Maxillofac Surg 43:177–182

    Article  CAS  PubMed  Google Scholar 

  5. Irvine GH, Bowerman JE (1985) Mandibular keratocysts: surgical management. Br J Oral Maxillofac Surg 23:204

    Article  CAS  PubMed  Google Scholar 

  6. Schmidt BL, Pogrel MA (2001) The use of enucleation and liquid nitrogen cryotherapy in the management of odontogenic keratocysts. J Oral Maxillofac Surg 59:720

    Article  CAS  PubMed  Google Scholar 

  7. Stoelinga PJ (2001) Long-term follow-up on keratocysts treated according to a defined protocol. Int J Oral Maxillofac Surg 30:14

    Article  CAS  PubMed  Google Scholar 

  8. Bramley P (1974) The odontogenic keratocyst—an approach to treatment. Int J Oral Surg 3:337

    Article  CAS  PubMed  Google Scholar 

  9. Bataineh AB, al Qudah M (1998) Treatment of mandibular odontogenic keratocysts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86:42

    Article  CAS  PubMed  Google Scholar 

  10. Ahlfors E, Larsson A, Sjogren S (1984) The odontogenic keratocyst: a benign cystic tumor? J Oral Maxillofac Surg 42:10

    Article  CAS  PubMed  Google Scholar 

  11. Shear M (2002) The aggressive nature of the odontogenic keratocyst: Is it a benign cystic neoplasm? Part 1. Clinical and early experimental evidence of aggressive behavior. Oral Oncol 38:219

    Article  PubMed  Google Scholar 

  12. Shear M (2002) The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 2 Proliferation and genetic studies. Oral Oncol 38:323

    Article  CAS  PubMed  Google Scholar 

  13. Shear M (2002) The aggressive nature of the odontogenic keratocyst: Is it a benign cystic neoplasm? Part 3. Immunocytochemistry of cytokeratin and other epithelial cell markers. Oral Oncol 38:07

    Google Scholar 

  14. Voorsmit RACA (1985) The incredible keratocyst: a new approach to treatment. Dtsch Zahnlrztl Z 40:641

    CAS  Google Scholar 

  15. Stoelinga PJW, Bronkhorst FB (1988) The incidence, multiple presentation and recurrence of aggressive cysts of the jaws. J Craniomaxillofac Surg 16:184

    Article  CAS  PubMed  Google Scholar 

  16. Frerich B, Cornelius CP, Wlethijlter H (1994) Critical time of exposure of the rabbit inferior aiveoiar nerve to Carnoy’s solution. J Oral Maxillofac Surg 52:599–606

    Article  CAS  PubMed  Google Scholar 

  17. Browne RM (1971) The odontogenic keratocyst: histological features and their correlation with clinical behavior. Br Dent J 131:249

    Article  CAS  PubMed  Google Scholar 

  18. Brannon RB (1976) The odontogenic keratocyst—a clinicopathologic study of 312 cases. Part I. Clinical features. Oral Surg 42:54

    Article  CAS  PubMed  Google Scholar 

  19. Voorsmit RA, Stoelinga PJ, van Haelst VJ (1981) The management of keratocysts. J Maxillofac Surg 9:228

    Article  CAS  PubMed  Google Scholar 

  20. Brondum N, Jensen VJ (1991) Recurrence and decompression treatment: a long-term follow-up of forty-four cases. Oral Surg Oral Med Oral Pathol 72:265

    Article  CAS  PubMed  Google Scholar 

  21. Williams TP, Connor FA (1994) Surgical management of the odontogenic keratocyst: aggressive approach. J Oral Maxillofac Surg 52:964

    Article  CAS  PubMed  Google Scholar 

  22. Voorsmit RACA (1984) The incredible keratocyst (thesis). University of Nijmegen, The Netherlands

    Google Scholar 

  23. Pogrel MA, Regezi J, Fong B et al (1998) Liquid nitrogen cryotherapy and immediate bone grafting: an animal model. J Oral Maxillofac Surg 56(suppl):53

    Google Scholar 

  24. Vedtofte P, Praetorius F (1979) Recurrence of the odontogenic keratocyst in relation to clinical and histologic features. Int J Oral Surg 8:412

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kiran Rao.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rao, K., Kumar, S. The Use of Enucleation and Chemical Cauterization (Carnoy’s) in the Management of Odontogenic Keratocyst of the Jaws. Indian J Otolaryngol Head Neck Surg 66, 8–12 (2014). https://doi.org/10.1007/s12070-012-0523-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-012-0523-8

Keywords

Navigation