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Erschienen in: Clinical and Translational Oncology 2/2015

01.02.2015 | Research Article

Impact of initial FDG PET/CT in the management plan of patients with locally advanced head and neck cancer

verfasst von: F. Arias, V. Chicata, M. J. García-Velloso, G. Asín, M. Uzcanga, C. Eito, I. Quilez, A. Viudez, J. Saenz, I. Hernández, C. Caicedo, M. Errasti, M. Barrado, F. García-Bragado

Erschienen in: Clinical and Translational Oncology | Ausgabe 2/2015

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Abstract

Objective

To determine the impact of initial FDG PET/CT staging on clinical stage and the management plan in patients with locally advanced head and neck cancer (LAHNC).

Materials and methods

We retrospectively reviewed the records of 72 consecutive patients (2007–2010) staged with PET/CT and conventional CT with tumours of hypopharynx/larynx (26 patients, 36 %), oral cavity (17 patients, 24 %), oropharynx (16 patients, 22 %), nasopharynx (12 patients, 17 %), and others (2 %). The impact of PET/CT on management plans was considered high when PET/CT changed the planned treatment modality or treatment intent, and intramodality changes were considered as minor changes with low impact.

Results

FDG PET/CT changed the stage in 27 patients and had high impact on the management plan in 12 % of patients (detection of distant metastases in 6 patients and stage II in 2 patients). Intramodality changes were more frequent: FDG PET/CT altered the TNM stage in 18/72 (25 %) of patients, upstaging N stage in 90 % of patients with low impact.

Conclusions

Initial FDG PET/CT staging not only improves stage but also affects the management plan in LAHNC patients.
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Metadaten
Titel
Impact of initial FDG PET/CT in the management plan of patients with locally advanced head and neck cancer
verfasst von
F. Arias
V. Chicata
M. J. García-Velloso
G. Asín
M. Uzcanga
C. Eito
I. Quilez
A. Viudez
J. Saenz
I. Hernández
C. Caicedo
M. Errasti
M. Barrado
F. García-Bragado
Publikationsdatum
01.02.2015
Verlag
Springer Milan
Erschienen in
Clinical and Translational Oncology / Ausgabe 2/2015
Print ISSN: 1699-048X
Elektronische ISSN: 1699-3055
DOI
https://doi.org/10.1007/s12094-014-1204-8

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