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Clinical and Translational Oncology

Erschienen in:

11.01.2022 | Review Article

Ytrrium-90 transarterial radioembolization in patients with gastrointestinal malignancies

verfasst von: D. Viñal, A. Minaya-Bravo, I. Prieto, J. Feliu, N. Rodriguez-Salas

Erschienen in: Clinical and Translational Oncology | Ausgabe 5/2022

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Abstract

Transarterial radioembolization (TARE) with yttrium-90 (Y90) is a promising alternative strategy to treat liver tumors and liver metastasis from colorectal cancer (CRC), as it selectively delivers radioactive isotopes to the tumor via the hepatic artery, sparring surrounding liver tissue. The landscape of TARE indications is constantly evolving. This strategy is considered for patients with hepatocellular carcinoma (HCC) with liver-confined disease and preserved liver function in whom neither TACE nor systemic therapy is possible. In patients with liver metastases from CRC, TARE is advised when other chemotherapeutic options have failed. Recent phase III trials have not succeeded to prove benefit in overall survival; however, it has helped to better understand the patients that may benefit from TARE based on subgroup analysis. New strategies and treatment combinations are being investigated in ongoing clinical trials. The aim of this review is to summarize the clinical applications of TARE in patients with gastrointestinal malignancies.

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Titel: Ytrrium-90 transarterial radioembolization in patients with gastrointestinal malignancies
verfasst von: D. Viñal
A. Minaya-Bravo
I. Prieto
J. Feliu
N. Rodriguez-Salas
Publikationsdatum: 11.01.2022
Verlag: Springer International Publishing
Erschienen in: Clinical and Translational Oncology / Ausgabe 5/2022
Print ISSN: 1699-048X
Elektronische ISSN: 1699-3055
DOI: https://doi.org/10.1007/s12094-021-02745-z

Neu im Fachgebiet Onkologie

16.04.2024 | Maligne primäre ZNS-Tumoren | Nachrichten

Springer Medizin

Ytrrium-90 transarterial radioembolization in patients with gastrointestinal malignancies

Abstract

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Springer Medizin

Abstract

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