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Head and Neck Pathology

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01.06.2010 | Case Report

Extraneural Sclerosing Perineurioma of the Buccal Mucosa: A Case Report and Clinicopathologic Review

verfasst von: Vikki L. Noonan, David J. Greene, Gilbert Brodsky, Sadru P. Kabani

Erschienen in: Head and Neck Pathology | Ausgabe 2/2010

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Abstract

The perineurioma is an infrequently encountered benign peripheral nerve sheath tumor composed of a clonal proliferation of perineurial cells. Rare cases of perineurioma have been reported in the oral cavity. An extraneural sclerosing perineurioma arising in the buccal mucosa of a 17-year-old male is presented. Histopathologically, the tumor is composed of a well circumscribed nodular proliferation of spindle cells arranged in a storiform growth pattern, in some areas subtly arranged around vascular channels. The tumor cells reveal positive immunostaining for epithelial membrane antigen (EMA), collagen type IV and vimentin, and negative immunostaining for S-100 protein, consistent with a perineurial origin. To the best of our knowledge, this case represents the first report of an extraneural sclerosing perineurioma involving the oral cavity.

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Titel: Extraneural Sclerosing Perineurioma of the Buccal Mucosa: A Case Report and Clinicopathologic Review
verfasst von: Vikki L. Noonan
David J. Greene
Gilbert Brodsky
Sadru P. Kabani
Publikationsdatum: 01.06.2010
Verlag: Humana Press Inc
Erschienen in: Head and Neck Pathology / Ausgabe 2/2010
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-010-0175-5

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