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Erschienen in: Head and Neck Pathology 1/2016

01.03.2016 | Special Issue: Sinonasal Tract Pathology. Guest Editors: Justin Bishop, MD and Alessandro Franchi, MD

Update on Select Benign Mesenchymal and Meningothelial Sinonasal Tract Lesions

verfasst von: Lester D. R. Thompson, Julie C. Fanburg-Smith

Erschienen in: Head and Neck Pathology | Ausgabe 1/2016

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Abstract

Several benign and malignant mesenchymal and meningothelial lesions may preferentially affect or extend into the sinonasal tract. Glomangiopericytoma (GPC, formerly sinonasal-type hemangiopericytoma) is a specific tumor with a predilection to the sinonasal tract. Sinonasal tract polyps with stromal atypia (antrochoanal polyp) demonstrate unique histologic findings in the sinonasal tract. Juvenile nasopharyngeal angiofibroma (JNA) arises from specialized tissue in this location. Meningioma may develop as direct extension from its intracranial counterpart or as an ectopic tumor. Selected benign mesenchymal tumors may arise in the sinonasal tract and pose a unique differential diagnostic consideration, such as solitary fibrous tumor and GPC or lobular capillary hemangioma and JNA. Although benign and malignant vascular, fibrous, fatty, skeletal muscle, and nerve sheath tumors may occur in this location, this paper focuses on a highly select group of rare benign sinonasal tract tumors with their clinicopathological and molecular findings, and differential diagnosis.
Literatur
2.
Zurück zum Zitat Gold JS, Antonescu CR, Hajdu C, et al. Clinicopathologic correlates of solitary fibrous tumors. Cancer. 2002;94:1057–68.CrossRefPubMed Gold JS, Antonescu CR, Hajdu C, et al. Clinicopathologic correlates of solitary fibrous tumors. Cancer. 2002;94:1057–68.CrossRefPubMed
3.
Zurück zum Zitat Suster S, Nascimento AG, Miettinen M, et al. Solitary fibrous tumors of soft tissue. A clinicopathologic and immunohistochemical study of 12 cases. Am J Surg Pathol. 1995;19:1257–66.CrossRefPubMed Suster S, Nascimento AG, Miettinen M, et al. Solitary fibrous tumors of soft tissue. A clinicopathologic and immunohistochemical study of 12 cases. Am J Surg Pathol. 1995;19:1257–66.CrossRefPubMed
4.
Zurück zum Zitat Miettinen M, Sarlomo-Rikala M, Kovatich AJ. Cell-type- and tumour-type-related patterns of bcl-2 reactivity in mesenchymal cells and soft tissue tumours. Virchows Arch. 1998;433:255–60.CrossRefPubMed Miettinen M, Sarlomo-Rikala M, Kovatich AJ. Cell-type- and tumour-type-related patterns of bcl-2 reactivity in mesenchymal cells and soft tissue tumours. Virchows Arch. 1998;433:255–60.CrossRefPubMed
5.
Zurück zum Zitat Miettinen M, Paal E, Lasota J, et al. Gastrointestinal glomus tumors: a clinicopathologic, immunohistochemical, and molecular genetic study of 32 cases. Am J Surg Pathol. 2002;26:301–11.CrossRefPubMed Miettinen M, Paal E, Lasota J, et al. Gastrointestinal glomus tumors: a clinicopathologic, immunohistochemical, and molecular genetic study of 32 cases. Am J Surg Pathol. 2002;26:301–11.CrossRefPubMed
6.
Zurück zum Zitat Thompson LD, Miettinen M, Wenig BM. Sinonasal-type hemangiopericytoma: a clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. Am J Surg Pathol. 2003;27:737–49.CrossRefPubMed Thompson LD, Miettinen M, Wenig BM. Sinonasal-type hemangiopericytoma: a clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. Am J Surg Pathol. 2003;27:737–49.CrossRefPubMed
7.
Zurück zum Zitat Haller F, Bieg M, Moskalev EA, et al. Recurrent mutations within the amino-terminal region of beta-catenin are probable key molecular driver events in sinonasal hemangiopericytoma. Am J Pathol. 2015;185:563–71.CrossRefPubMed Haller F, Bieg M, Moskalev EA, et al. Recurrent mutations within the amino-terminal region of beta-catenin are probable key molecular driver events in sinonasal hemangiopericytoma. Am J Pathol. 2015;185:563–71.CrossRefPubMed
8.
Zurück zum Zitat Lasota J, Felisiak-Golabek A, Aly FZ, et al. Nuclear expression and gain-of-function beta-catenin mutation in glomangiopericytoma (sinonasal-type hemangiopericytoma): insight into pathogenesis and a diagnostic marker. Mod Pathol. 2015;28:715–20.CrossRefPubMed Lasota J, Felisiak-Golabek A, Aly FZ, et al. Nuclear expression and gain-of-function beta-catenin mutation in glomangiopericytoma (sinonasal-type hemangiopericytoma): insight into pathogenesis and a diagnostic marker. Mod Pathol. 2015;28:715–20.CrossRefPubMed
9.
Zurück zum Zitat Fletcher CD. Hemangiopericytoma–a dying breed? Reappraisal of an “entity” and its variant. A hypothesis. Curr Diagn Pathol. 1994;1:19–23.CrossRef Fletcher CD. Hemangiopericytoma–a dying breed? Reappraisal of an “entity” and its variant. A hypothesis. Curr Diagn Pathol. 1994;1:19–23.CrossRef
10.
Zurück zum Zitat Granter SR, Badizadegan K, Fletcher CD. Myofibromatosis in adults, glomangiopericytoma, and myopericytoma: a spectrum of tumors showing perivascular myoid differentiation. Am J Surg Pathol. 1998;22:513–25.CrossRefPubMed Granter SR, Badizadegan K, Fletcher CD. Myofibromatosis in adults, glomangiopericytoma, and myopericytoma: a spectrum of tumors showing perivascular myoid differentiation. Am J Surg Pathol. 1998;22:513–25.CrossRefPubMed
11.
Zurück zum Zitat Catalano PJ, Brandwein M, Shah DK, et al. Sinonasal hemangiopericytomas: a clinicopathologic and immunohistochemical study of seven cases. Head Neck. 1996;18:42–53.CrossRefPubMed Catalano PJ, Brandwein M, Shah DK, et al. Sinonasal hemangiopericytomas: a clinicopathologic and immunohistochemical study of seven cases. Head Neck. 1996;18:42–53.CrossRefPubMed
12.
Zurück zum Zitat Compagno J, Hyams VJ. Hemangiopericytoma-like intranasal tumors. A clinicopathologic study of 23 cases. Am J Clin Pathol. 1976;66:672–83.PubMed Compagno J, Hyams VJ. Hemangiopericytoma-like intranasal tumors. A clinicopathologic study of 23 cases. Am J Clin Pathol. 1976;66:672–83.PubMed
13.
Zurück zum Zitat Billings KR, Fu YS, Calcaterra TC, et al. Hemangiopericytoma of the head and neck. Am J Otolaryngol. 2000;21:238–43.CrossRefPubMed Billings KR, Fu YS, Calcaterra TC, et al. Hemangiopericytoma of the head and neck. Am J Otolaryngol. 2000;21:238–43.CrossRefPubMed
14.
Zurück zum Zitat el Naggar AK, Batsakis JG, Garcia GM, et al. Sinonasal hemangiopericytomas. A clinicopathologic and DNA content study. Arch Otolaryngol Head Neck Surg. 1992;118:134–7.CrossRefPubMed el Naggar AK, Batsakis JG, Garcia GM, et al. Sinonasal hemangiopericytomas. A clinicopathologic and DNA content study. Arch Otolaryngol Head Neck Surg. 1992;118:134–7.CrossRefPubMed
15.
Zurück zum Zitat Brandwein-Gensler M, Siegal GP. Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia. Head Neck Pathol. 2012;6:64–74.PubMedCentralCrossRefPubMed Brandwein-Gensler M, Siegal GP. Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia. Head Neck Pathol. 2012;6:64–74.PubMedCentralCrossRefPubMed
16.
Zurück zum Zitat Marianowski R, Wassef M, Herman P, et al. Nasal haemangiopericytoma: report of two cases with literature review. J Laryngol Otol. 1999;113:199–206.PubMed Marianowski R, Wassef M, Herman P, et al. Nasal haemangiopericytoma: report of two cases with literature review. J Laryngol Otol. 1999;113:199–206.PubMed
17.
Zurück zum Zitat Eichhorn JH, Dickersin GR, Bhan AK, et al. Sinonasal hemangiopericytoma. A reassessment with electron microscopy, immunohistochemistry, and long-term follow-up. Am J Surg Pathol. 1990;14:856–66.CrossRefPubMed Eichhorn JH, Dickersin GR, Bhan AK, et al. Sinonasal hemangiopericytoma. A reassessment with electron microscopy, immunohistochemistry, and long-term follow-up. Am J Surg Pathol. 1990;14:856–66.CrossRefPubMed
18.
Zurück zum Zitat Kowalski PJ, Paulino AF. Proliferation index as a prognostic marker in hemangiopericytoma of the head and neck. Head Neck. 2001;23:492–6.CrossRefPubMed Kowalski PJ, Paulino AF. Proliferation index as a prognostic marker in hemangiopericytoma of the head and neck. Head Neck. 2001;23:492–6.CrossRefPubMed
19.
Zurück zum Zitat Enzinger FM, Smith BH. Hemangiopericytoma. An analysis of 106 cases. Hum Pathol. 1976;7:61–82.CrossRefPubMed Enzinger FM, Smith BH. Hemangiopericytoma. An analysis of 106 cases. Hum Pathol. 1976;7:61–82.CrossRefPubMed
20.
Zurück zum Zitat Folpe AL, Devaney K, Weiss SW. Lipomatous hemangiopericytoma: a rare variant of hemangiopericytoma that may be confused with liposarcoma. Am J Surg Pathol. 1999;23:1201–7.CrossRefPubMed Folpe AL, Devaney K, Weiss SW. Lipomatous hemangiopericytoma: a rare variant of hemangiopericytoma that may be confused with liposarcoma. Am J Surg Pathol. 1999;23:1201–7.CrossRefPubMed
21.
Zurück zum Zitat Nielsen GP, Dickersin GR, Provenzal JM, et al. Lipomatous hemangiopericytoma. A histologic, ultrastructural and immunohistochemical study of a unique variant of hemangiopericytoma. Am J Surg Pathol. 1995;19:748–56.CrossRefPubMed Nielsen GP, Dickersin GR, Provenzal JM, et al. Lipomatous hemangiopericytoma. A histologic, ultrastructural and immunohistochemical study of a unique variant of hemangiopericytoma. Am J Surg Pathol. 1995;19:748–56.CrossRefPubMed
22.
Zurück zum Zitat Guillou L, Gebhard S, Coindre JM. Lipomatous hemangiopericytoma: a fat-containing variant of solitary fibrous tumor? Clinicopathologic, immunohistochemical, and ultrastructural analysis of a series in favor of a unifying concept. Hum Pathol. 2000;31:1108–15.CrossRefPubMed Guillou L, Gebhard S, Coindre JM. Lipomatous hemangiopericytoma: a fat-containing variant of solitary fibrous tumor? Clinicopathologic, immunohistochemical, and ultrastructural analysis of a series in favor of a unifying concept. Hum Pathol. 2000;31:1108–15.CrossRefPubMed
23.
Zurück zum Zitat Agaimy A, Barthelmeß S, Boltze C, et al. Phenotypical and molecular distinctness of sinonasal haemangiopericytoma compared to solitary fibrous tumour of the sinonasal tract. Histopathology. 2014;65:667–73.CrossRefPubMed Agaimy A, Barthelmeß S, Boltze C, et al. Phenotypical and molecular distinctness of sinonasal haemangiopericytoma compared to solitary fibrous tumour of the sinonasal tract. Histopathology. 2014;65:667–73.CrossRefPubMed
24.
Zurück zum Zitat Gengler C, Guillou L. Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology. 2006;48:63–74.CrossRefPubMed Gengler C, Guillou L. Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology. 2006;48:63–74.CrossRefPubMed
25.
Zurück zum Zitat Nappi O, Ritter JH, Pettinato G, et al. Hemangiopericytoma: histopathological pattern or clinicopathologic entity? Semin Diagn Pathol. 1995;12:221–32.PubMed Nappi O, Ritter JH, Pettinato G, et al. Hemangiopericytoma: histopathological pattern or clinicopathologic entity? Semin Diagn Pathol. 1995;12:221–32.PubMed
26.
Zurück zum Zitat Porter PL, Bigler SA, McNutt M, et al. The immunophenotype of hemangiopericytomas and glomus tumors, with special reference to muscle protein expression: an immunohistochemical study and review of the literature. Mod Pathol. 1991;4:46–52.PubMed Porter PL, Bigler SA, McNutt M, et al. The immunophenotype of hemangiopericytomas and glomus tumors, with special reference to muscle protein expression: an immunohistochemical study and review of the literature. Mod Pathol. 1991;4:46–52.PubMed
27.
28.
Zurück zum Zitat Klaus A, Birchmeier W. Wnt signalling and its impact on development and cancer. Nat Rev Cancer. 2008;8:387–98.CrossRefPubMed Klaus A, Birchmeier W. Wnt signalling and its impact on development and cancer. Nat Rev Cancer. 2008;8:387–98.CrossRefPubMed
29.
Zurück zum Zitat Huss S, Nehles J, Binot E. β-catenin (CTNNB1) mutations and clinicopathological features of mesenteric desmoid-type fibromatosis. Histopathology. 2013;62:294–304.CrossRefPubMed Huss S, Nehles J, Binot E. β-catenin (CTNNB1) mutations and clinicopathological features of mesenteric desmoid-type fibromatosis. Histopathology. 2013;62:294–304.CrossRefPubMed
30.
Zurück zum Zitat Fukunaga M, Ushigome S, Nomura K, et al. Solitary fibrous tumor of the nasal cavity and orbit. Pathol Int. 1995;45:952–7.CrossRefPubMed Fukunaga M, Ushigome S, Nomura K, et al. Solitary fibrous tumor of the nasal cavity and orbit. Pathol Int. 1995;45:952–7.CrossRefPubMed
31.
Zurück zum Zitat Witkin GB, Rosai J. Solitary fibrous tumor of the upper respiratory tract. A report of six cases. Am J Surg Pathol. 1991;15:842–8.CrossRefPubMed Witkin GB, Rosai J. Solitary fibrous tumor of the upper respiratory tract. A report of six cases. Am J Surg Pathol. 1991;15:842–8.CrossRefPubMed
32.
Zurück zum Zitat Zukerberg LR, Rosenberg AE, Randolph G, et al. Solitary fibrous tumor of the nasal cavity and paranasal sinuses. Am J Surg Pathol. 1991;15:126–30.CrossRefPubMed Zukerberg LR, Rosenberg AE, Randolph G, et al. Solitary fibrous tumor of the nasal cavity and paranasal sinuses. Am J Surg Pathol. 1991;15:126–30.CrossRefPubMed
33.
Zurück zum Zitat Kempson RL, Fletcher CDM, Evans HL, et al. Fibrous and myofibroblastic tumors. In: Kempson RL, Fletcher CDM, Evans HL, Hendrickson MR, Sibley RK, editors. Atlas of tumor pathology: tumors of the soft tissues. Bethesda: Armed Forces Institute of Pathology; 2001. p. 23–112. Kempson RL, Fletcher CDM, Evans HL, et al. Fibrous and myofibroblastic tumors. In: Kempson RL, Fletcher CDM, Evans HL, Hendrickson MR, Sibley RK, editors. Atlas of tumor pathology: tumors of the soft tissues. Bethesda: Armed Forces Institute of Pathology; 2001. p. 23–112.
34.
Zurück zum Zitat Cox DP, Daniels T, Jordan RC. Solitary fibrous tumor of the head and neck. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:79–84.CrossRefPubMed Cox DP, Daniels T, Jordan RC. Solitary fibrous tumor of the head and neck. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:79–84.CrossRefPubMed
35.
Zurück zum Zitat Rakheja D, Molberg KH, Roberts CA. Immunohistochemical expression of beta-catenin in solitary fibrous tumors. Arch Pathol Lab Med. 2005;129:776–9.PubMed Rakheja D, Molberg KH, Roberts CA. Immunohistochemical expression of beta-catenin in solitary fibrous tumors. Arch Pathol Lab Med. 2005;129:776–9.PubMed
36.
Zurück zum Zitat Chmielecki J, Crago AM, Rosenberg M. Whole exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors. Nat Genet. 2013;45:131–2.PubMedCentralCrossRefPubMed Chmielecki J, Crago AM, Rosenberg M. Whole exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors. Nat Genet. 2013;45:131–2.PubMedCentralCrossRefPubMed
37.
Zurück zum Zitat Furusato E, Valenzuela IA, Fanburg-Smith JC, et al. Orbital solitary fibrous tumor: encompassing terminology for hemangiopericytoma, giant cell angiofibroma, and fibrous histiocytoma of the orbit: reappraisal of 41 cases. Hum Pathol. 2011;42:120–8.CrossRefPubMed Furusato E, Valenzuela IA, Fanburg-Smith JC, et al. Orbital solitary fibrous tumor: encompassing terminology for hemangiopericytoma, giant cell angiofibroma, and fibrous histiocytoma of the orbit: reappraisal of 41 cases. Hum Pathol. 2011;42:120–8.CrossRefPubMed
38.
Zurück zum Zitat Li Z, Wang J, Zhu Q, et al. Huge solitary fibrous tumor of the pleura with hypoglycemia and hypokalemia: a case report. Ann Thorac Cardiovasc Surg. 2014;20:165–8.CrossRefPubMed Li Z, Wang J, Zhu Q, et al. Huge solitary fibrous tumor of the pleura with hypoglycemia and hypokalemia: a case report. Ann Thorac Cardiovasc Surg. 2014;20:165–8.CrossRefPubMed
39.
Zurück zum Zitat Baldi GG, Stacchiotti S, Mauro V, et al. Solitary fibrous tumor of all sites: outcome of late recurrences in 14 patients. Clin Sarcoma Res. 2013;3:4.PubMedCentralCrossRefPubMed Baldi GG, Stacchiotti S, Mauro V, et al. Solitary fibrous tumor of all sites: outcome of late recurrences in 14 patients. Clin Sarcoma Res. 2013;3:4.PubMedCentralCrossRefPubMed
40.
Zurück zum Zitat Xue Y, Chai G, Xiao F, et al. Post-operative radiotherapy for the treatment of malignant solitary fibrous tumor of the nasal and paranasal area. Jpn J Clin Oncol. 2014;44:926–31.CrossRefPubMed Xue Y, Chai G, Xiao F, et al. Post-operative radiotherapy for the treatment of malignant solitary fibrous tumor of the nasal and paranasal area. Jpn J Clin Oncol. 2014;44:926–31.CrossRefPubMed
41.
42.
Zurück zum Zitat Demicco EG, Park MS, Araujo DM, et al. Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model. Mod Pathol. 2012;25:1298–306.CrossRefPubMed Demicco EG, Park MS, Araujo DM, et al. Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model. Mod Pathol. 2012;25:1298–306.CrossRefPubMed
44.
Zurück zum Zitat Stacchiotti S, Tortoreto M, Baldi GG, et al. Preclinical and clinical evidence of activity of pazopanib in solitary fibrous tumour. Eur J Cancer. 2014;50:3021–8.CrossRefPubMed Stacchiotti S, Tortoreto M, Baldi GG, et al. Preclinical and clinical evidence of activity of pazopanib in solitary fibrous tumour. Eur J Cancer. 2014;50:3021–8.CrossRefPubMed
45.
Zurück zum Zitat Tazzari M, Negri T, Rini F, et al. Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy. Br J Cancer. 2014;111:1350–62.PubMedCentralCrossRefPubMed Tazzari M, Negri T, Rini F, et al. Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy. Br J Cancer. 2014;111:1350–62.PubMedCentralCrossRefPubMed
46.
Zurück zum Zitat Yamada Y, Kohashi K, Fushimi F, et al. Activation of the Akt-mTOR pathway and receptor tyrosine kinase in patients with solitary fibrous tumors. Cancer. 2014;120:864–76.CrossRefPubMed Yamada Y, Kohashi K, Fushimi F, et al. Activation of the Akt-mTOR pathway and receptor tyrosine kinase in patients with solitary fibrous tumors. Cancer. 2014;120:864–76.CrossRefPubMed
47.
Zurück zum Zitat Mosquera JM, Fletcher CD. Expanding the spectrum of malignant progression in solitary fibrous tumors: a study of 8 cases with a discrete anaplastic component–is this dedifferentiated SFT? Am J Surg Pathol. 2009;33:1314–21.CrossRefPubMed Mosquera JM, Fletcher CD. Expanding the spectrum of malignant progression in solitary fibrous tumors: a study of 8 cases with a discrete anaplastic component–is this dedifferentiated SFT? Am J Surg Pathol. 2009;33:1314–21.CrossRefPubMed
48.
Zurück zum Zitat Doyle LA, Vivero M, Fletcher CD, et al. Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics. Mod Pathol. 2014;27:390–5.CrossRefPubMed Doyle LA, Vivero M, Fletcher CD, et al. Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics. Mod Pathol. 2014;27:390–5.CrossRefPubMed
49.
Zurück zum Zitat Yoshida A, Tsuta K, Ohno M, et al. STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors. Am J Surg Pathol. 2014;38:552–9.CrossRefPubMed Yoshida A, Tsuta K, Ohno M, et al. STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors. Am J Surg Pathol. 2014;38:552–9.CrossRefPubMed
50.
Zurück zum Zitat Demicco EG, Harms PW, Patel RM, et al. Extensive survey of STAT6 expression in a large series of mesenchymal tumors. Am J Clin Pathol. 2015;143:672–82.CrossRefPubMed Demicco EG, Harms PW, Patel RM, et al. Extensive survey of STAT6 expression in a large series of mesenchymal tumors. Am J Clin Pathol. 2015;143:672–82.CrossRefPubMed
51.
Zurück zum Zitat Mohajeri A, Tayebwa J, Collin A, et al. Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor. Genes Chromosomes Cancer. 2013;52:873–86.CrossRefPubMed Mohajeri A, Tayebwa J, Collin A, et al. Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor. Genes Chromosomes Cancer. 2013;52:873–86.CrossRefPubMed
52.
Zurück zum Zitat Demicco EG, Wani K, Fox PS, et al. Histologic variability in solitary fibrous tumors reflects angiogenic and growth factor signaling pathway alterations. Hum Pathol. 2015;46:1015–26.CrossRefPubMed Demicco EG, Wani K, Fox PS, et al. Histologic variability in solitary fibrous tumors reflects angiogenic and growth factor signaling pathway alterations. Hum Pathol. 2015;46:1015–26.CrossRefPubMed
53.
Zurück zum Zitat Akaike K, Kurisaki-Arakawa A, Hara K, et al. Distinct clinicopathological features of NAB2-STAT6 fusion gene variants in solitary fibrous tumor with emphasis on the acquisition of highly malignant potential. Hum Pathol. 2015;46:347–56.CrossRefPubMed Akaike K, Kurisaki-Arakawa A, Hara K, et al. Distinct clinicopathological features of NAB2-STAT6 fusion gene variants in solitary fibrous tumor with emphasis on the acquisition of highly malignant potential. Hum Pathol. 2015;46:347–56.CrossRefPubMed
55.
Zurück zum Zitat Balikci HH, Ozkul MH, Uvacin O, et al. Antrochoanal polyposis: analysis of 34 cases. Eur Arch Otorhinolaryngol. 2013;270:1651–4.CrossRefPubMed Balikci HH, Ozkul MH, Uvacin O, et al. Antrochoanal polyposis: analysis of 34 cases. Eur Arch Otorhinolaryngol. 2013;270:1651–4.CrossRefPubMed
56.
Zurück zum Zitat Frosini P, Picarella G, De CE. Antrochoanal polyp: analysis of 200 cases. Acta Otorhinolaryngol Ital. 2009;29:21–6.PubMedCentralPubMed Frosini P, Picarella G, De CE. Antrochoanal polyp: analysis of 200 cases. Acta Otorhinolaryngol Ital. 2009;29:21–6.PubMedCentralPubMed
57.
Zurück zum Zitat Ozcan C, Zeren H, Talas DU, et al. Antrochoanal polyp: a transmission electron and light microscopic study. Eur Arch Otorhinolaryngol. 2005;262:55–60.CrossRefPubMed Ozcan C, Zeren H, Talas DU, et al. Antrochoanal polyp: a transmission electron and light microscopic study. Eur Arch Otorhinolaryngol. 2005;262:55–60.CrossRefPubMed
58.
Zurück zum Zitat Mahfouz ME, Elsheikh MN, Ghoname NF. Molecular profile of the antrochoanal polyp: up-regulation of basic fibroblast growth factor and transforming growth factor beta in maxillary sinus mucosa. Am J Rhinol. 2006;20:466–70.CrossRefPubMed Mahfouz ME, Elsheikh MN, Ghoname NF. Molecular profile of the antrochoanal polyp: up-regulation of basic fibroblast growth factor and transforming growth factor beta in maxillary sinus mucosa. Am J Rhinol. 2006;20:466–70.CrossRefPubMed
59.
Zurück zum Zitat Montague ML, McGarry GW. Familial antrochoanal polyposis–a case report. Eur Arch Otorhinolaryngol. 2004;261:507–8.CrossRefPubMed Montague ML, McGarry GW. Familial antrochoanal polyposis–a case report. Eur Arch Otorhinolaryngol. 2004;261:507–8.CrossRefPubMed
60.
Zurück zum Zitat Nikakhlagh S, Rahim F, Saki N, et al. Antrochoanal polyps: report of 94 cases and review the literature. Niger J Med. 2012;21:156–9.PubMed Nikakhlagh S, Rahim F, Saki N, et al. Antrochoanal polyps: report of 94 cases and review the literature. Niger J Med. 2012;21:156–9.PubMed
61.
Zurück zum Zitat Aydin O, Keskin G, Ustundag E, et al. Choanal polyps: an evaluation of 53 cases. Am J Rhinol. 2007;21:164–8.CrossRefPubMed Aydin O, Keskin G, Ustundag E, et al. Choanal polyps: an evaluation of 53 cases. Am J Rhinol. 2007;21:164–8.CrossRefPubMed
62.
Zurück zum Zitat Sarafraz M, Niazi A, Araghi S. The prevalence of clinical presentations and pathological characteristics of antrochoanal polyp. Niger J Med. 2015;24:12–6.PubMed Sarafraz M, Niazi A, Araghi S. The prevalence of clinical presentations and pathological characteristics of antrochoanal polyp. Niger J Med. 2015;24:12–6.PubMed
63.
Zurück zum Zitat Skladzien J, Litwin JA, Nowogrodzka-Zagorska M, et al. Morphological and clinical characteristics of antrochoanal polyps: comparison with chronic inflammation-associated polyps of the maxillary sinus. Auris Nasus Larynx. 2001;28:137–41.CrossRefPubMed Skladzien J, Litwin JA, Nowogrodzka-Zagorska M, et al. Morphological and clinical characteristics of antrochoanal polyps: comparison with chronic inflammation-associated polyps of the maxillary sinus. Auris Nasus Larynx. 2001;28:137–41.CrossRefPubMed
64.
Zurück zum Zitat Atighechi S, Baradaranfar MH, Karimi G, et al. Antrochoanal polyp: a comparative study of endoscopic endonasal surgery alone and endoscopic endonasal plus mini-Caldwell technique. Eur Arch Otorhinolaryngol. 2009;266:1245–8.CrossRefPubMed Atighechi S, Baradaranfar MH, Karimi G, et al. Antrochoanal polyp: a comparative study of endoscopic endonasal surgery alone and endoscopic endonasal plus mini-Caldwell technique. Eur Arch Otorhinolaryngol. 2009;266:1245–8.CrossRefPubMed
65.
Zurück zum Zitat Chung SK, Chang BC, Dhong HJ. Surgical, radiologic, and histologic findings of the antrochoanal polyp. Am J Rhinol. 2002;16:71–6.PubMed Chung SK, Chang BC, Dhong HJ. Surgical, radiologic, and histologic findings of the antrochoanal polyp. Am J Rhinol. 2002;16:71–6.PubMed
66.
Zurück zum Zitat Mallick S, Benson R, Bhasker S, et al. Long-term treatment outcomes of juvenile nasopharyngeal angiofibroma treated with radiotherapy. Acta Otorhinolaryngol Ital. 2015;35:75–9.PubMedCentralPubMed Mallick S, Benson R, Bhasker S, et al. Long-term treatment outcomes of juvenile nasopharyngeal angiofibroma treated with radiotherapy. Acta Otorhinolaryngol Ital. 2015;35:75–9.PubMedCentralPubMed
67.
Zurück zum Zitat Carlos R, Thompson LD, Netto AC, et al. Epstein-Barr virus and human herpes virus-8 are not associated with juvenile nasopharyngeal angiofibroma. Head Neck Pathol. 2008;2:145–9.PubMedCentralCrossRefPubMed Carlos R, Thompson LD, Netto AC, et al. Epstein-Barr virus and human herpes virus-8 are not associated with juvenile nasopharyngeal angiofibroma. Head Neck Pathol. 2008;2:145–9.PubMedCentralCrossRefPubMed
68.
Zurück zum Zitat Silveira SM, Custodio Domingues MA, Butugan O, et al. Tumor microenvironmental genomic alterations in juvenile nasopharyngeal angiofibroma. Head Neck. 2012;34:485–92.CrossRefPubMed Silveira SM, Custodio Domingues MA, Butugan O, et al. Tumor microenvironmental genomic alterations in juvenile nasopharyngeal angiofibroma. Head Neck. 2012;34:485–92.CrossRefPubMed
69.
Zurück zum Zitat Maniglia MP, Ribeiro ME, Costa NM, et al. Molecular pathogenesis of juvenile nasopharyngeal angiofibroma in brazilian patients. Pediatr Hematol Oncol. 2013;30:616–22.CrossRefPubMed Maniglia MP, Ribeiro ME, Costa NM, et al. Molecular pathogenesis of juvenile nasopharyngeal angiofibroma in brazilian patients. Pediatr Hematol Oncol. 2013;30:616–22.CrossRefPubMed
70.
Zurück zum Zitat Renkonen S, Kankainen M, Hagstrom J, et al. Systems-level analysis of clinically different phenotypes of juvenile nasopharyngeal angiofibromas. Laryngoscope. 2012;122:2728–35.CrossRefPubMed Renkonen S, Kankainen M, Hagstrom J, et al. Systems-level analysis of clinically different phenotypes of juvenile nasopharyngeal angiofibromas. Laryngoscope. 2012;122:2728–35.CrossRefPubMed
71.
Zurück zum Zitat Schiff M, Gonzalez AM, Ong M, et al. Juvenile nasopharyngeal angiofibroma contain an angiogenic growth factor: basic FGF. Laryngoscope. 1992;102:940–5.CrossRefPubMed Schiff M, Gonzalez AM, Ong M, et al. Juvenile nasopharyngeal angiofibroma contain an angiogenic growth factor: basic FGF. Laryngoscope. 1992;102:940–5.CrossRefPubMed
72.
Zurück zum Zitat Smith SC, Patel RM, Lucas DR, et al. Sinonasal lobular capillary hemangioma: a clinicopathologic study of 34 cases characterizing potential for local recurrence. Head Neck Pathol. 2013;7:129–34.PubMedCentralCrossRefPubMed Smith SC, Patel RM, Lucas DR, et al. Sinonasal lobular capillary hemangioma: a clinicopathologic study of 34 cases characterizing potential for local recurrence. Head Neck Pathol. 2013;7:129–34.PubMedCentralCrossRefPubMed
73.
Zurück zum Zitat Dyduch G, Okon K, Mierzynski W. Benign vascular proliferations–an immunohistochemical and comparative study. Pol J Pathol. 2004;55:59–64.PubMed Dyduch G, Okon K, Mierzynski W. Benign vascular proliferations–an immunohistochemical and comparative study. Pol J Pathol. 2004;55:59–64.PubMed
74.
Zurück zum Zitat Yuan K, Lin MT. The roles of vascular endothelial growth factor and angiopoietin-2 in the regression of pregnancy pyogenic granuloma. Oral Dis. 2004;10:179–85.CrossRefPubMed Yuan K, Lin MT. The roles of vascular endothelial growth factor and angiopoietin-2 in the regression of pregnancy pyogenic granuloma. Oral Dis. 2004;10:179–85.CrossRefPubMed
75.
Zurück zum Zitat Nelson BL, Thompson LD. Sinonasal tract angiosarcoma: a clinicopathologic and immunophenotypic study of 10 cases with a review of the literature. Head Neck Pathol. 2007;1:1–12.PubMedCentralCrossRefPubMed Nelson BL, Thompson LD. Sinonasal tract angiosarcoma: a clinicopathologic and immunophenotypic study of 10 cases with a review of the literature. Head Neck Pathol. 2007;1:1–12.PubMedCentralCrossRefPubMed
76.
Zurück zum Zitat Louis DN, Ohgaki H, Wiestler OD, Cavenee WK. World health organization classification of tumours of the central nervous system. 4th ed. Lyon: IARC Press; 2007. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK. World health organization classification of tumours of the central nervous system. 4th ed. Lyon: IARC Press; 2007.
77.
Zurück zum Zitat Shibuya M. Pathology and molecular genetics of meningioma: recent advances. Neurol Med Chir (Tokyo). 2015;55:14–27.CrossRef Shibuya M. Pathology and molecular genetics of meningioma: recent advances. Neurol Med Chir (Tokyo). 2015;55:14–27.CrossRef
78.
Zurück zum Zitat Perzin KH, Pushparaj N. Nonepithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. A clinicopathologic study. XIII: Meningiomas. Cancer. 1984;54:1860–9.CrossRefPubMed Perzin KH, Pushparaj N. Nonepithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. A clinicopathologic study. XIII: Meningiomas. Cancer. 1984;54:1860–9.CrossRefPubMed
79.
80.
Zurück zum Zitat Thompson LD, Gyure KA. Extracranial sinonasal tract meningiomas: a clinicopathologic study of 30 cases with a review of the literature. Am J Surg Pathol. 2000;24:640–50.CrossRefPubMed Thompson LD, Gyure KA. Extracranial sinonasal tract meningiomas: a clinicopathologic study of 30 cases with a review of the literature. Am J Surg Pathol. 2000;24:640–50.CrossRefPubMed
81.
Zurück zum Zitat Moulin G, Coatrieux A, Gillot JC, et al. Plaque-like meningioma involving the temporal bone, sinonasal cavities and both parapharyngeal spaces: CT and MRI. Neuroradiology. 1994;36:629–31.CrossRefPubMed Moulin G, Coatrieux A, Gillot JC, et al. Plaque-like meningioma involving the temporal bone, sinonasal cavities and both parapharyngeal spaces: CT and MRI. Neuroradiology. 1994;36:629–31.CrossRefPubMed
82.
Zurück zum Zitat Kaley TJ, Wen P, Schiff D, et al. Phase II trial of sunitinib for recurrent and progressive atypical and anaplastic meningioma. Neuro Oncol. 2015;17:116–21.PubMedCentralCrossRefPubMed Kaley TJ, Wen P, Schiff D, et al. Phase II trial of sunitinib for recurrent and progressive atypical and anaplastic meningioma. Neuro Oncol. 2015;17:116–21.PubMedCentralCrossRefPubMed
83.
Zurück zum Zitat Perry A, Stafford SL, Scheithauer BW, et al. Meningioma grading. An analysis of histologic parameters. Am J Surg Pathol. 1997;21:1455–65.CrossRefPubMed Perry A, Stafford SL, Scheithauer BW, et al. Meningioma grading. An analysis of histologic parameters. Am J Surg Pathol. 1997;21:1455–65.CrossRefPubMed
84.
85.
Zurück zum Zitat Perry A, Scheithauer BW, Stafford SL, et al. “Malignancy” in meningiomas: a clinicopathologic study of 116 patients, with grading implications. Cancer. 1999;85:2046–56.PubMed Perry A, Scheithauer BW, Stafford SL, et al. “Malignancy” in meningiomas: a clinicopathologic study of 116 patients, with grading implications. Cancer. 1999;85:2046–56.PubMed
86.
Zurück zum Zitat Schweizer L, Koelsche C, Sahm F, et al. Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein. Acta Neuropathol. 2013;125:651–8.CrossRefPubMed Schweizer L, Koelsche C, Sahm F, et al. Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein. Acta Neuropathol. 2013;125:651–8.CrossRefPubMed
87.
Zurück zum Zitat Miller R, DeCandio ML, Xon-Mah Y, et al. Molecular targets and treatment of meningioma. J Neurol Neurosurg. 2014;1:10001011. Miller R, DeCandio ML, Xon-Mah Y, et al. Molecular targets and treatment of meningioma. J Neurol Neurosurg. 2014;1:10001011.
88.
Zurück zum Zitat Domingues P, Gonzalez-Tablas M, Otero A, et al. Genetic/molecular alterations of meningiomas and the signaling pathways targeted. Oncotarget. 2015;6:10671–88.PubMedCentralCrossRefPubMed Domingues P, Gonzalez-Tablas M, Otero A, et al. Genetic/molecular alterations of meningiomas and the signaling pathways targeted. Oncotarget. 2015;6:10671–88.PubMedCentralCrossRefPubMed
89.
Zurück zum Zitat Gusella JF, Ramesh V, MacCollin M, et al. Merlin: the neurofibromatosis 2 tumor suppressor. Biochim Biophys Acta. 1999;1423:M29–36.PubMed Gusella JF, Ramesh V, MacCollin M, et al. Merlin: the neurofibromatosis 2 tumor suppressor. Biochim Biophys Acta. 1999;1423:M29–36.PubMed
90.
Zurück zum Zitat Stawski R, Piaskowski S, Stoczynska-Fidelus E, et al. Reduced expression of ELAVL4 in male meningioma patients. Brain Tumor Pathol. 2013;30:160–6.CrossRefPubMed Stawski R, Piaskowski S, Stoczynska-Fidelus E, et al. Reduced expression of ELAVL4 in male meningioma patients. Brain Tumor Pathol. 2013;30:160–6.CrossRefPubMed
92.
Zurück zum Zitat Thompson LDR, Wieneke JA, Miettinen M. Sinonasal tract melanomas: A clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol. 2003;27:594–611.CrossRefPubMed Thompson LDR, Wieneke JA, Miettinen M. Sinonasal tract melanomas: A clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol. 2003;27:594–611.CrossRefPubMed
93.
Zurück zum Zitat Wenig BM, Vinh TN, Smirniotopoulos JG, et al. Aggressive psammomatoid ossifying fibromas of the sinonasal region. A clinicopathologic study of a distinct group of fibro-osseous lesions. Cancer. 1995;76:1155–65.CrossRefPubMed Wenig BM, Vinh TN, Smirniotopoulos JG, et al. Aggressive psammomatoid ossifying fibromas of the sinonasal region. A clinicopathologic study of a distinct group of fibro-osseous lesions. Cancer. 1995;76:1155–65.CrossRefPubMed
Metadaten
Titel
Update on Select Benign Mesenchymal and Meningothelial Sinonasal Tract Lesions
verfasst von
Lester D. R. Thompson
Julie C. Fanburg-Smith
Publikationsdatum
01.03.2016
Verlag
Springer US
Erschienen in
Head and Neck Pathology / Ausgabe 1/2016
Elektronische ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-016-0697-6

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