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Erschienen in: Annals of Nuclear Medicine 2/2014

01.02.2014 | Original Article

Influence of left ventricular geometry on thallium-201 gated single-photon emission tomographic findings in patients with known or suspected coronary artery disease

verfasst von: Satoshi Kurisu, Toshitaka Iwasaki, Hiroki Ikenaga, Noriaki Watanabe, Tadanao Higaki, Takashi Shimonaga, Ken Ishibashi, Naoya Mitsuba, Yoshihiro Dohi, Yasuki Kihara

Erschienen in: Annals of Nuclear Medicine | Ausgabe 2/2014

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Abstract

Background

Recent studies have shown good correlations between echocardiography and Tl-201 gated single-photon emission computed tomography (SPECT) for the assessment of left ventricular volumes and ejection fraction. We assessed how left ventricular geometry affected correlations between these values measured by the 2 methods in patients with known or suspected coronary artery disease.

Methods and results

There were 109 patients with normal left ventricular geometry, 20 patients with concentric remodeling, 32 patients with eccentric hypertrophy and 28 patients with concentric hypertrophy. In all 4 groups, there were good correlations between end-diastolic volume (EDV) and end-systolic volume (ESV) values measured by echocardiography and quantitative gated SPECT (QGS). EDV and ESV values measured by QGS were significantly underestimated than those measured by echocardiography except for ESV in eccentric hypertrophy. In all 4 groups, ejection fraction (EF) value measured by echocardiography significantly correlated with that measured by QGS, but Bland–Altman plot showed a proportional error. EF value measured by QGS was likely to be overestimated when EF value increased from the median value, and to be underestimated when EF value decreased from the median value especially in concentric remodeling.

Conclusions

Tl-201 gated SPECT is a useful tool for the assessment of left ventricular volumes and function, but it requires methodological considerations according to left ventricular geometry.
Literatur
1.
Zurück zum Zitat Yang KT, Chen HD. Evaluation of global and regional left ventricular function using technetium-99m sestamibi ECG-gated single-photon emission tomography. Eur J Nucl Med. 1998;25:515–21.PubMedCrossRef Yang KT, Chen HD. Evaluation of global and regional left ventricular function using technetium-99m sestamibi ECG-gated single-photon emission tomography. Eur J Nucl Med. 1998;25:515–21.PubMedCrossRef
2.
Zurück zum Zitat Yoshioka J, Hasegawa S, Yamaguchi H, Tokita N, Paul AK, Xiuli M, et al. Left ventricular volumes and ejection fraction calculated from quantitative electrocardiographic-gated 99mTc-tetrofosmin myocardial SPECT. J Nucl Med. 1999;40:1693–8.PubMed Yoshioka J, Hasegawa S, Yamaguchi H, Tokita N, Paul AK, Xiuli M, et al. Left ventricular volumes and ejection fraction calculated from quantitative electrocardiographic-gated 99mTc-tetrofosmin myocardial SPECT. J Nucl Med. 1999;40:1693–8.PubMed
3.
Zurück zum Zitat Rozanski A, Nichols K, Yao SS, Malholtra S, Cohen R, DePuey EG. Development and application of normal limits for left ventricular ejection fraction and volume measurements from 99mTc-sestamibi myocardial perfusion gates SPECT. J Nucl Med. 2000;41:1445–50.PubMed Rozanski A, Nichols K, Yao SS, Malholtra S, Cohen R, DePuey EG. Development and application of normal limits for left ventricular ejection fraction and volume measurements from 99mTc-sestamibi myocardial perfusion gates SPECT. J Nucl Med. 2000;41:1445–50.PubMed
4.
Zurück zum Zitat DePuey EG, Parmett S, Ghesani M, Rozanski A, Nichols K, Salensky H. Comparison of Tc-99m sestamibi and Tl-201 gated perfusion SPECT. J Nucl Cardiol. 1999;6:278–85.PubMedCrossRef DePuey EG, Parmett S, Ghesani M, Rozanski A, Nichols K, Salensky H. Comparison of Tc-99m sestamibi and Tl-201 gated perfusion SPECT. J Nucl Cardiol. 1999;6:278–85.PubMedCrossRef
5.
Zurück zum Zitat Hyun IY, Kwan J, Park KS, Lee WH. Reproducibility of Tl-201 and Tc-99m sestamibi gated myocardial perfusion SPECT measurement of myocardial function. J Nucl Cardiol. 2001;8:182–7.PubMedCrossRef Hyun IY, Kwan J, Park KS, Lee WH. Reproducibility of Tl-201 and Tc-99m sestamibi gated myocardial perfusion SPECT measurement of myocardial function. J Nucl Cardiol. 2001;8:182–7.PubMedCrossRef
6.
Zurück zum Zitat Bacher-Stier C, Müller S, Pachinger O, Strolz S, Erler H, Moncayo R, et al. Thallium-201 gated single-photon emission tomography for the assessment of left ventricular ejection fraction and regional wall motion abnormalities in comparison with two-dimensional echocardiography. Eur J Nucl Med. 1999;26:1533–40.PubMedCrossRef Bacher-Stier C, Müller S, Pachinger O, Strolz S, Erler H, Moncayo R, et al. Thallium-201 gated single-photon emission tomography for the assessment of left ventricular ejection fraction and regional wall motion abnormalities in comparison with two-dimensional echocardiography. Eur J Nucl Med. 1999;26:1533–40.PubMedCrossRef
7.
Zurück zum Zitat Cwajg E, Cwajg J, He ZX, Hwang WS, Keng F, Nagueh SF, et al. Gated myocardial perfusion tomography for the assessment of left ventricular function and volumes: comparison with echocardiography. J Nucl Med. 1999;40:1857–65.PubMed Cwajg E, Cwajg J, He ZX, Hwang WS, Keng F, Nagueh SF, et al. Gated myocardial perfusion tomography for the assessment of left ventricular function and volumes: comparison with echocardiography. J Nucl Med. 1999;40:1857–65.PubMed
8.
Zurück zum Zitat Patel CD, Nadig MR, Kurien S, Barai S, Narang R, Malhotra A. Left ventricular ejection fraction and volumes on rest gated 201Tl perfusion SPECT: comparison with two-dimensional echocardiography. Nucl Med Commun. 2006;27:425–9.PubMedCrossRef Patel CD, Nadig MR, Kurien S, Barai S, Narang R, Malhotra A. Left ventricular ejection fraction and volumes on rest gated 201Tl perfusion SPECT: comparison with two-dimensional echocardiography. Nucl Med Commun. 2006;27:425–9.PubMedCrossRef
9.
Zurück zum Zitat Harpaz D, Asman A, Kuperstein R, Boaz M, Chouraqui P. Left ventricular ejection fraction assessment by Tl-201 gated SPECT: a comparison with echocardiography. Clin Cardiol. 2010;33:E56–62.PubMedCrossRef Harpaz D, Asman A, Kuperstein R, Boaz M, Chouraqui P. Left ventricular ejection fraction assessment by Tl-201 gated SPECT: a comparison with echocardiography. Clin Cardiol. 2010;33:E56–62.PubMedCrossRef
10.
Zurück zum Zitat Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr. 1989;2:358–67.PubMed Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr. 1989;2:358–67.PubMed
11.
Zurück zum Zitat Otterstad JE, Froeland G, John Sutton M, Holme I. Accuracy and reproducibility of biplane two-dimensional echocardiographic measurements of left ventricular dimensions and function. Eur Heart J. 1997;18:507–13.PubMedCrossRef Otterstad JE, Froeland G, John Sutton M, Holme I. Accuracy and reproducibility of biplane two-dimensional echocardiographic measurements of left ventricular dimensions and function. Eur Heart J. 1997;18:507–13.PubMedCrossRef
12.
Zurück zum Zitat Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, Chamber Quantification Writing Group, American Society of Echocardiography’s Guidelines and Standards Committee, European Association of Echocardiography, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005;18:1440–63.PubMedCrossRef Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, Chamber Quantification Writing Group, American Society of Echocardiography’s Guidelines and Standards Committee, European Association of Echocardiography, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005;18:1440–63.PubMedCrossRef
13.
Zurück zum Zitat Takasaki K, Miyata M, Imamura M, Yuasa T, Kuwahara E, Kubota K, et al. Left ventricular dysfunction assessed by cardiac time interval analysis among different geometric patterns in untreated hypertension. Circ J. 2012;76:1409–14.PubMedCrossRef Takasaki K, Miyata M, Imamura M, Yuasa T, Kuwahara E, Kubota K, et al. Left ventricular dysfunction assessed by cardiac time interval analysis among different geometric patterns in untreated hypertension. Circ J. 2012;76:1409–14.PubMedCrossRef
14.
Zurück zum Zitat Germano G, Kiat H, Kavanagh PB, Moriel M, Mazzanti M, Su HT, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med. 1995;36:2138–47.PubMed Germano G, Kiat H, Kavanagh PB, Moriel M, Mazzanti M, Su HT, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med. 1995;36:2138–47.PubMed
15.
Zurück zum Zitat Wright GA, McDade M, Keeble W, Martin W, Hutton I. Quantitative gated SPECT myocardial perfusion imaging with 201Tl: an assessment of the limitations. Nucl Med Commun. 2000;21:1147–51.PubMedCrossRef Wright GA, McDade M, Keeble W, Martin W, Hutton I. Quantitative gated SPECT myocardial perfusion imaging with 201Tl: an assessment of the limitations. Nucl Med Commun. 2000;21:1147–51.PubMedCrossRef
16.
Zurück zum Zitat El-Maghraby TA, El-Rahman NA. Clinical relevance of left ventricular volumes and function assessed by gated SPECT in paediatric patients. Int J Cardiovasc Imaging. 2004;20:127–34.PubMedCrossRef El-Maghraby TA, El-Rahman NA. Clinical relevance of left ventricular volumes and function assessed by gated SPECT in paediatric patients. Int J Cardiovasc Imaging. 2004;20:127–34.PubMedCrossRef
17.
Zurück zum Zitat Germano G, Berman DS. On the accuracy and reproducibility of quantitative gated myocardial perfusion SPECT. J Nucl Med. 1999;40:810–3.PubMed Germano G, Berman DS. On the accuracy and reproducibility of quantitative gated myocardial perfusion SPECT. J Nucl Med. 1999;40:810–3.PubMed
Metadaten
Titel
Influence of left ventricular geometry on thallium-201 gated single-photon emission tomographic findings in patients with known or suspected coronary artery disease
verfasst von
Satoshi Kurisu
Toshitaka Iwasaki
Hiroki Ikenaga
Noriaki Watanabe
Tadanao Higaki
Takashi Shimonaga
Ken Ishibashi
Naoya Mitsuba
Yoshihiro Dohi
Yasuki Kihara
Publikationsdatum
01.02.2014
Verlag
Springer Japan
Erschienen in
Annals of Nuclear Medicine / Ausgabe 2/2014
Print ISSN: 0914-7187
Elektronische ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-013-0786-5

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