Erschienen in:
20.04.2020 | Short Communication
AI approach of cycle-consistent generative adversarial networks to synthesize PET images to train computer-aided diagnosis algorithm for dementia
verfasst von:
Yuichi Kimura, Aya Watanabe, Takahiro Yamada, Shogo Watanabe, Takashi Nagaoka, Mitsutaka Nemoto, Koichi Miyazaki, Kohei Hanaoka, Hayato Kaida, Kazunari Ishii
Erschienen in:
Annals of Nuclear Medicine
|
Ausgabe 7/2020
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Abstract
Objective
An artificial intelligence (AI)-based algorithm typically requires a considerable amount of training data; however, few training images are available for dementia with Lewy bodies and frontotemporal lobar degeneration. Therefore, this study aims to present the potential of cycle-consistent generative adversarial networks (CycleGAN) to obtain enough number of training images for AI-based computer-aided diagnosis (CAD) algorithms for diagnosing dementia.
Methods
We trained CycleGAN using 43 amyloid-negative and 45 positive images in slice-by-slice.
Results
The CycleGAN can be used to synthesize reasonable amyloid-positive images, and the continuity of slices was preserved.
Discussion
Our results show that CycleGAN has the potential to generate a sufficient number of training images for CAD of dementia.