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Erschienen in: Annals of Nuclear Medicine 7/2020

20.04.2020 | Short Communication

AI approach of cycle-consistent generative adversarial networks to synthesize PET images to train computer-aided diagnosis algorithm for dementia

verfasst von: Yuichi Kimura, Aya Watanabe, Takahiro Yamada, Shogo Watanabe, Takashi Nagaoka, Mitsutaka Nemoto, Koichi Miyazaki, Kohei Hanaoka, Hayato Kaida, Kazunari Ishii

Erschienen in: Annals of Nuclear Medicine | Ausgabe 7/2020

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Abstract

Objective

An artificial intelligence (AI)-based algorithm typically requires a considerable amount of training data; however, few training images are available for dementia with Lewy bodies and frontotemporal lobar degeneration. Therefore, this study aims to present the potential of cycle-consistent generative adversarial networks (CycleGAN) to obtain enough number of training images for AI-based computer-aided diagnosis (CAD) algorithms for diagnosing dementia.

Methods

We trained CycleGAN using 43 amyloid-negative and 45 positive images in slice-by-slice.

Results

The CycleGAN can be used to synthesize reasonable amyloid-positive images, and the continuity of slices was preserved.

Discussion

Our results show that CycleGAN has the potential to generate a sufficient number of training images for CAD of dementia.
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Metadaten
Titel
AI approach of cycle-consistent generative adversarial networks to synthesize PET images to train computer-aided diagnosis algorithm for dementia
verfasst von
Yuichi Kimura
Aya Watanabe
Takahiro Yamada
Shogo Watanabe
Takashi Nagaoka
Mitsutaka Nemoto
Koichi Miyazaki
Kohei Hanaoka
Hayato Kaida
Kazunari Ishii
Publikationsdatum
20.04.2020
Verlag
Springer Singapore
Erschienen in
Annals of Nuclear Medicine / Ausgabe 7/2020
Print ISSN: 0914-7187
Elektronische ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-020-01468-5

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