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Annals of Behavioral Medicine

Erschienen in:

01.06.2014 | Original Article

Depression Treatment Enhances Adherence to Antiretroviral Therapy: a Meta-Analysis

verfasst von: Nancy L. Sin, PhD, M. Robin DiMatteo, PhD

Erschienen in: Annals of Behavioral Medicine | Ausgabe 3/2014

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Abstract

Background

Depression is a risk factor for nonadherence to HIV/AIDS treatment.

Purpose

A meta-analysis was conducted to examine whether treatment of depression and psychological distress improves antiretroviral therapy adherence.

Methods

PubMed and PsycINFO databases were systematically searched for relevant articles. Studies that reported an association between depression treatment (or an intervention with a component addressing mental health) and antiretroviral adherence were included.

Results

Across 29 studies of 12,243 persons living with HIV/AIDS, treatment of depression and psychological distress improved antiretroviral adherence (p < 0.001). The odds of a person adhering were 83 % better if he/she was treated for depression. Greater improvements in adherence were found for samples with lower CD4 counts or more severe depression, for interventions specifically targeting depression (versus addressing mental health as a secondary objective), longer treatments, and observational studies.

Conclusions

These findings support the need for detection and treatment of depression among persons living with HIV/AIDS.

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Titel: Depression Treatment Enhances Adherence to Antiretroviral Therapy: a Meta-Analysis
verfasst von: Nancy L. Sin, PhD
M. Robin DiMatteo, PhD
Publikationsdatum: 01.06.2014
Verlag: Springer US
Erschienen in: Annals of Behavioral Medicine / Ausgabe 3/2014
Print ISSN: 0883-6612
Elektronische ISSN: 1532-4796
DOI: https://doi.org/10.1007/s12160-013-9559-6

Neu in den Fachgebieten Neurologie und Psychiatrie

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

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Depression Treatment Enhances Adherence to Antiretroviral Therapy: a Meta-Analysis

Abstract

Background

Purpose

Methods

Results

Conclusions

Neu in den Fachgebieten Neurologie und Psychiatrie

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Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Background

Purpose

Methods

Results

Conclusions

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